Primary Site >> Pancreatic Cancer

Gene >> L1CAM

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Ref: Absence of L1 in pancreatic masses distinguishes adenocarcinomas from poorly differentiated neuroendocrine carcinomas.
PMID: 16619519
Ref: Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells.
PMID: 17086212
Ref: Blockade of natural killer cell-mediated lysis by NCAM140 expressed on tumor cells.
PMID: 17294447
Ref: Enhanced L1CAM expression on pancreatic tumor endothelium mediates selective tumor cell transmigration.
PMID: 18931829
Ref: Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.
PMID: 19435915
Ref: Positive expression of L1-CAM is associated with perineural invasion and poor outcome in pancreatic ductal adenocarcinoma.
PMID: 20162456
Ref: Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets?
PMID: 20459551
Ref: A migration signature and plasma biomarker panel for pancreatic adenocarcinoma.
PMID: 21071578
Ref: Downregulation of L1CAM inhibits proliferation, invasion and arrests cell cycle progression in pancreatic cancer cells in vitro.
PMID: 24660028
Ref: The fatal alliance of cancer and T cells: How pancreatic tumor cells gather immunosuppressive T cells.
PMID: 25114835
Ref: Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment.
PMID: 25860483
Ref: CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development.
PMID: 26137395
Ref: [Pancreatic acinar neoplasms : Comparative molecular characterization].
PMID: 27807633
Ref: Celecoxib suppresses proliferation and metastasis of pancreatic cancer cells by down-regulating STAT3 / NF-kB and L1CAM activities.
PMID: 29525378
Ref: L1CAM induces perineural invasion of pancreas cancer cells by upregulation of metalloproteinase expression.
PMID: 30171263