Primary Site >> Stomach Cancer
Gene >> KLF4
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Ref: Kruppel-like factor 4 (KLF4) represses histidine decarboxylase gene expression through an upstream Sp1 site and downstream gastrin responsive elements. PMID: 14670968 |
Ref: Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. PMID: 15760920 Ref: Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression. PMID: 15805274 Ref: Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. PMID: 15825076 |
Ref: Emerging role of KLF4 in human gastrointestinal cancer. PMID: 16219632 Ref: Loss of Kruppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression. PMID: 17085651 |
Ref: KLF4 suppresses transformation of pre-B cells by ABL oncogenes. PMID: 16954505 Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. PMID: 17273778 Ref: Genetic and epigenetic analysis of the KLF4 gene in gastric cancer. PMID: 17614846 |
Ref: KLF4 positively regulates human ghrelin expression. PMID: 19327128 Ref: Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma. PMID: 19737957 |
Ref: An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer. PMID: 20043075 Ref: Dopamine, by acting through its D2 receptor, inhibits insulin-like growth factor-I (IGF-I)-induced gastric cancer cell proliferation via up-regulation of Kruppel-like factor 4 through down-regulation of IGF-IR and AKT phosphorylation. PMID: 21075859 |
Ref: Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. PMID: 22155367 Ref: Kruppel-like factor 4 negatively regulates beta-catenin expression and inhibits the proliferation, invasion and metastasis of gastric cancer. PMID: 22407433 Ref: Altered expression of Kruppel-like factor 4 and beta-catenin in human gastric cancer. PMID: 22783383 Ref: [Association between gut-enriched Kruppel-like factor and prognosis of patients with gastric cancer]. PMID: 22851081 |
Ref: KLF4 expression and apoptosis-related markers in gastric cancer. PMID: 24065485 |
Ref: Epigallocatechin-3-gallate regulates the expression of Kruppel-like factor 4 through myocyte enhancer factor 2A. PMID: 23884787 Ref: Concomitant upregulation of nucleostemin and downregulation of Sox2 and Klf4 in gastric adenocarcinoma. PMID: 24763828 Ref: MicroRNA-206 suppresses gastric cancer cell growth and metastasis. PMID: 24855559 Ref: Synergistic anti-tumor effect of KLF4 and curcumin in human gastric carcinoma cell line. PMID: 25292057 |
Ref: MiR-32 promotes gastric carcinoma tumorigenesis by targeting Kruppel-like factor 4. PMID: 26471298 Ref: Arsenic sulfide inhibits cell migration and invasion of gastric cancer in vitro and in vivo. PMID: 26487802 Ref: Evodiamine, a novel inhibitor of the Wnt pathway, inhibits the self-renewal of gastric cancer stem cells. PMID: 26497016 Ref: Bioinformatics identification of potentially involved microRNAs in Tibetan with gastric cancer based on microRNA profiling. PMID: 26692821 |
Ref: All-trans retinoic acid targets gastric cancer stem cells and inhibits patient-derived gastric carcinoma tumor growth. PMID: 27157616 Ref: KLF4 deletion alters gastric cell lineage and induces MUC2 expression. PMID: 27277677 |
Ref: Prognostic significance of KLF4 expression in gastric cancer. PMID: 28356964 Ref: KLF16 promotes proliferation in gastric cancer cells via regulating p21 and CDK4. PMID: 28670390 Ref: Long noncoding RNA LINC00673 epigenetically suppresses KLF4 by interacting with EZH2 and DNMT1 in gastric cancer. PMID: 29221147 |
Ref: Kruppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition. PMID: 28719351 Ref: Kruppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition. PMID: 29367428 Ref: Ibuprofen reduces cell proliferation through inhibiting Wnt/beta catenin signaling pathway in gastric cancer stem cells. PMID: 29512256 Ref: Research progress on the forkhead box C1. PMID: 29552326 Ref: Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer. PMID: 29719612 Ref: PODXL, negatively regulated by KLF4, promotes the EMT and metastasis and serves as a novel prognostic indicator of gastric cancer. PMID: 29748877 Ref: Role of Kruppel-like factor 4 in regulating inhibitor of apoptosis-stimulating protein of p53 in the progression of gastric cancer. PMID: 29849786 Ref: Negative Regulation of Kruppel-Like Factor 4 on microRNA-106a at Upstream Transcriptional Level and the Role in Gastric Cancer Metastasis. PMID: 29948558 Ref: Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer. PMID: 29985646 |