Primary Site >> Colorectal Cancer
Gene >> KITLG
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Ref: Expression of c-kit and kit ligand in human colon carcinoma cells. PMID: 7694350 |
Ref: Immunocytological detection of micrometastatic cells: comparative evaluation of findings in the peritoneal cavity and the bone marrow of gastric, colorectal and pancreatic cancer patients. PMID: 8168992 |
Ref: Interleukin 4 down-regulates expression of c-kit and autocrine stem cell factor in human colorectal carcinoma cells. PMID: 8519688 |
Ref: Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1. PMID: 9207920 |
Ref: High-dose topotecan with granulocyte-colony stimulating factor in fluoropyrimidine-refractory colorectal cancer: a phase II and pharmacodynamic study. PMID: 9553662 |
Ref: Clinical implications of lymph node micrometastases in patients with colorectal cancers. A case control study. PMID: 10575311 |
Ref: Elevated expression of SAG/ROC2/Rbx2/Hrt2 in human colon carcinomas: SAG does not induce neoplastic transformation, but antisense SAG transfection inhibits tumor cell growth. PMID: 11255265 Ref: Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. PMID: 11280787 |
Ref: Identification of tumor associated single-chain Fv by panning and screening antibody phage library using tumor cells. PMID: 12174367 Ref: Immunohistochemical staining for c-Kit (CD117) is a rare event in human colorectal carcinoma. PMID: 12453327 |
Ref: A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. PMID: 14516475 Ref: Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery. PMID: 14563921 |
Ref: Body fat accumulation and postoperative complications after abdominal surgery. PMID: 15098790 |
Ref: Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy. PMID: 16114015 Ref: CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. PMID: 16778892 Ref: KIT/stem cell factor expression in premalignant and malignant lesions of the colon mucosa in relationship to disease progression and outcomes. PMID: 16964380 |
Ref: Pretreatment serum levels of hematopoietic cytokines in patients with colorectal adenomas and cancer. PMID: 16520929 Ref: The FBXW7 beta-form is suppressed in human glioma cells. PMID: 17274947 Ref: Stem cell factor/c-kit receptor signaling enhances the proliferation and invasion of colorectal cancer cells through the PI3K/Akt pathway. PMID: 17410437 |
Ref: Effects of adjuvant chemotherapy on bone marrow mesenchymal stem cells of colorectal cancer patients. PMID: 18304729 |
Ref: Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice. PMID: 19106159 Ref: Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo. PMID: 19308290 Ref: beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt. PMID: 19797085 |
Ref: Association between activation of atypical NF-kappaB1 p105 signaling pathway and nuclear beta-catenin accumulation in colorectal carcinoma. PMID: 20027638 |
Ref: The perioperative granulocyte/lymphocyte ratio is a clinically relevant marker of surgical stress in patients with colorectal cancer. PMID: 21094053 Ref: FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation. PMID: 21282377 Ref: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction. PMID: 21368833 |
Ref: Defining components of the ss-catenin destruction complex and exploring its regulation and mechanisms of action during development. PMID: 22359584 Ref: Anticancer Activity of Self-Assembled Molecular Rectangles via Arene-Ruthenium Acceptors and a New Unsymmetrical Amide Ligand. PMID: 22639481 |
Ref: Protein kinase C-delta-mediated recycling of active KIT in colon cancer. PMID: 23881925 Ref: Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness. PMID: 24009080 |
Ref: Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division. PMID: 24500709 Ref: KITLG is a novel target of miR-34c that is associated with the inhibition of growth and invasion in colorectal cancer cells. PMID: 25213795 |
Ref: Maintenance of Clonogenic KIT(+) Human Colon Tumor Cells Requires Secretion of Stem Cell Factor by Differentiated Tumor Cells. PMID: 25962936 Ref: KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers. PMID: 26026391 Ref: The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer. PMID: 26114183 Ref: Coated chitosan nanoparticles encapsulating caspase 3 activator for effective treatment of colorectral cancer. PMID: 26334865 Ref: Greatwall promotes cell transformation by hyperactivating AKT in human malignancies. PMID: 26613407 Ref: Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo. PMID: 26674205 Ref: Interrupted E2F1-miR-34c-SCF negative feedback loop by hyper-methylation promotes colorectal cancer cell proliferation. PMID: 26704889 |
Ref: Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins. PMID: 26428235 Ref: Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation. PMID: 26744523 |
Ref: FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma. PMID: 27916606 Ref: Structural features and anticancer activity in vitro of fucoidan derivatives from brown alga Saccharina cichorioides. PMID: 27987862 Ref: Novel Palladium(II) Complexes that Influence Prominin-1/CD133 Expression and Stem Cell Factor Release in Tumor Cells. PMID: 28358339 Ref: SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma. PMID: 28383479 |
Ref: Identifying novel small molecule antagonists for mLST8 protein using computational approaches. PMID: 29041842 Ref: SCF/c-KIT signaling promotes mucus secretion of colonic goblet cells and development of mucinous colorectal adenocarcinoma. PMID: 30034943 Ref: (+)-Usnic Acid Inhibits Migration of c-KIT Positive Cells in Human Colorectal Cancer. PMID: 30298093 Ref: Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models. PMID: 30377568 |