Primary Site >> Colorectal Cancer

Gene >> IL12A

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Ref: Abnormal rectal cell proliferation and p52/p35 protein expression in patients with ulcerative colitis.
PMID: 8402594
Ref: In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity.
PMID: 9574551
Ref: Antibody-IL-12 fusion proteins are effective in SCID mouse models of prostate and colon carcinoma metastases.
PMID: 9637539
Ref: Construction and characterization of a triple-recombinant vaccinia virus encoding B7-1, interleukin 12, and a model tumor antigen.
PMID: 9862625
Ref: Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.
PMID: 10608348
Ref: Protective immunity is induced in murine colon carcinoma cells by the expression of interleukin-12 or interleukin-18, which activate type 1 helper T cells.
PMID: 10770633
Ref: Interferon-inducible protein 10 induction and inhibition of angiogenesis in vivo by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
PMID: 11245459
Ref: Intratumoral delivery of interleukin 12 expression plasmids with in vivo electroporation is effective for colon and renal cancer.
PMID: 11440620
Ref: Intratumoral delivery of p2CMVmIL-12 using water-soluble lipopolymers.
PMID: 11482984
Ref: Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy.
PMID: 12717836
Ref: Baculovirus P35 interacts with a subunit of human RNA polymerase II and can enhance promoter activity in human cells.
PMID: 14573806
Ref: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
PMID: 15611081
Ref: Polymorphisms within inflammatory genes and colorectal cancer.
PMID: 17062130
Ref: Formation and use of water-soluble lipopolymer-pDNA and lipopeptide-pDNA complexes.
PMID: 20147051
Ref: Monocytes expression of IL-12 related and IL-10 genes in association with development of colorectal cancer.
PMID: 23053983
Ref: Erythronium japonicum attenuates histopathological lung abnormalities in a mouse model of ovalbumin-induced asthma.
PMID: 27035741
Ref: Elevated level of interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3.
PMID: 27682874
Ref: Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice.
PMID: 29326691
Ref: Protumor Steering of Cancer Inflammation by p50 NF-kappaB Enhances Colorectal Cancer Progression.
PMID: 29588321