Primary Site >> Stomach Cancer

Gene >> HSPA5

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Ref: Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade.
PMID: 11719466
Ref: Trefoil factor 1 (TFF1/pS2) deficiency activates the unfolded protein response.
PMID: 12359958
Ref: Effect on tumor cells of blocking survival response to glucose deprivation.
PMID: 15339968
Ref: Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.
PMID: 16205636
Ref: Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer.
PMID: 17187227
Ref: Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.
PMID: 17971859
Ref: A new tumor-specific variant of GRP78 as target for antibody-based therapy.
PMID: 18268478
Ref: Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
PMID: 18482745
Ref: Efrapeptin J, a new down-regulator of the molecular chaperone GRP78 from a marine Tolypocladium sp.
PMID: 18667784
Ref: Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells.
PMID: 18829155
Ref: Effectiveness of HSV-tk suicide gene therapy driven by the Grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas.
PMID: 19277794
Ref: Grp78 promotes the invasion of hepatocellular carcinoma.
PMID: 20082722
Ref: The pathobiological behaviors and prognosis associated with Japanese gastric adenocarcinomas of pure WHO histological subtypes.
PMID: 20183797
Ref: Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer.
PMID: 20204278
Ref: Endoplasmic reticulum stress contributes to vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.
PMID: 20435408
Ref: Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer.
PMID: 21165559
Ref: Endoplasmic reticulum stress-mediated signaling pathway of gastric cancer apoptosis.
PMID: 22688017
Ref: Targeting to overexpressed glucose-regulated protein 78 in gastric cancer discovered by 2D DIGE improves the diagnostic and therapeutic efficacy of micelles-mediated system.
PMID: 22778057
Ref: Crosstalk between endoplasmic reticulum stress and oxidative stress in apoptosis induced by alpha-tocopheryl succinate in human gastric carcinoma cells.
PMID: 22676837
Ref: The unfolded protein response is activated in Helicobacter-induced gastric carcinogenesis in a non-cell autonomous manner.
PMID: 23108377
Ref: Novel targeted nuclear imaging agent for gastric cancer diagnosis: glucose-regulated protein 78 binding peptide-guided 111In-labeled polymeric micelles.
PMID: 23630420
Ref: A peptide derived from phage display library exhibits anti-tumor activity by targeting GRP78 in gastric cancer multidrug resistance cells.
PMID: 23792224
Ref: Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways.
PMID: 24260584
Ref: [GRP78 expression in gastric cancer and its clinical significance].
PMID: 24447482
Ref: Ultrafine particles of Ulmus davidiana var. japonica induce apoptosis of gastric cancer cells via activation of caspase and endoplasmic reticulum stress.
PMID: 24395528
Ref: Discovery of tumor markers for gastric cancer by proteomics.
PMID: 24404153
Ref: Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.
PMID: 24602846
Ref: Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl1 and BclxL and increasing Bax and CHOP protein expression.
PMID: 25270224
Ref: Decreased functional expression of Grp78 and Grp94 inhibits proliferation and attenuates apoptosis in a human gastric cancer cell line in vitro.
PMID: 25663878
Ref: Mechanism study of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR by iTRAQ-based proteomic analysis.
PMID: 25943993
Ref: ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression.
PMID: 25980581
Ref: KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78.
PMID: 26045166
Ref: BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy.
PMID: 26050197
Ref: 3,3'-diindolylmethane potentiates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of gastric cancer cells.
PMID: 26137077
Ref: Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis.
PMID: 26774454
Ref: Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.
PMID: 27040446
Ref: Recombinant Newcastle disease virus (rL-RVG) triggers autophagy and apoptosis in gastric carcinoma cells by inducing ER stress.
PMID: 27293989
Ref: Nobiletin Induces Protective Autophagy Accompanied by ER-Stress Mediated Apoptosis in Human Gastric Cancer SNU-16 Cells.
PMID: 27428937
Ref: E platinum, a newly synthesized platinum compound, induces apoptosis through ROS-triggered ER stress in gastric carcinoma cells.
PMID: 27061377
Ref: Oxysterol-Binding Protein-Related Protein 8 Inhibits Gastric Cancer Growth Through Induction of ER Stress, Inhibition of Wnt Signaling, and Activation of Apoptosis.
PMID: 27983927
Ref: Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
PMID: 28202509
Ref: Prognostic role of BiP/GRP78 expression as ER stress in patients with gastric adenocarcinoma.
PMID: 28854502
Ref: GRP78 positively regulates estrogenstimulated cell growth mediated by ERalpha36 in gastric cancer cells.
PMID: 28983626
Ref: The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
PMID: 29069845
Ref: Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1alpha and GRP78.
PMID: 29072683
Ref: Endoplasmic reticulum chaperone glucose-regulated protein 78 in gastric cancer: An emerging biomarker.
PMID: 29616092
Ref: Hyperbaric oxygen treatment sensitizes gastric cancer cells to melatonin-induced apoptosis through multiple pathways.
PMID: 29665051
Ref: Estrogen receptor-alpha36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
PMID: 29805694
Ref: Induction of ER Stress-Mediated Apoptosis by the Major Component 5,7,4'-Trimethoxyflavone Isolated from Kaempferia parviflora Tea Infusion.
PMID: 30273054
Ref: MicroRNA-495-3p inhibits multidrug resistance by modulating autophagy through GRP78/mTOR axis in gastric cancer.
PMID: 30341283