Primary Site >> Stomach Cancer
Gene >> HNF4A
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Ref: Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. PMID: 9823469 |
Ref: Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer. PMID: 10392898 |
Ref: Clinical significance of disordered beta-catenin expression pattern in human gastric cancers. PMID: 11984736 |
Ref: Mutational analysis of the beta-catenin gene in gastric carcinomas. PMID: 11125285 Ref: Genetic alterations in the human Tcf-4 gene in Japanese patients with sporadic gastrointestinal cancers with microsatellite instability. PMID: 11528255 Ref: Molecular cloning and characterization of LZIC, a novel gene encoding ICAT homologous protein with leucine zipper domain. PMID: 11712074 |
Ref: Molecular cloning and characterization of WRCH2 on human chromosome 15q15. PMID: 11956592 Ref: Molecular cloning and characterization of Strabismus 2 (STB2). PMID: 11956595 Ref: Frequent up-regulation of WNT5A mRNA in primary gastric cancer. PMID: 11956659 Ref: Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells. PMID: 12165812 Ref: Expression of WNT7A in human normal tissues and cancer, and regulation of WNT7A and WNT7B in human cancer. PMID: 12239632 Ref: Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells. PMID: 12460462 Ref: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. PMID: 12481159 |
Ref: 5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dose docetaxel (Taxotere)-cisplatin in advanced gastric carcinoma: a phase I-II trial. PMID: 15111343 |
Ref: Molecular evolution of Wnt2b orthologs. PMID: 15754012 Ref: Inhibition of beta-catenin-mediated transactivation by flavanone in AGS gastric cancer cells. PMID: 15883006 Ref: Comparative genomics on DKK2 and DKK4 orthologs. PMID: 16077958 Ref: Negative regulation of beta-catenin/Tcf signaling by naringenin in AGS gastric cancer cell. PMID: 16102728 |
Ref: Targeting the active beta-catenin pathway to treat cancer cells. PMID: 17121933 |
Ref: A phase I study of paclitaxel, cisplatin, and fluorouracil (TCF) for advanced gastric cancer. PMID: 16924496 Ref: Suppression of gastric cancer cell growth by targeting the beta-catenin/T-cell factor pathway. PMID: 17149756 Ref: Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells. PMID: 17160019 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Genetic and epigenetic analysis of the EPHB2 gene in gastric cancers. PMID: 17295683 Ref: Downregulated P1 promoter-driven hepatocyte nuclear factor-4alpha expression in human colorectal carcinoma is a new prognostic factor against liver metastasis. PMID: 17300672 Ref: Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research. PMID: 17664469 |
Ref: The aurora kinase A regulates GSK-3beta in gastric cancer cells. PMID: 19060929 Ref: Immunohistochemical staining for P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha may complement mucin phenotype of differentiated-type early gastric carcinoma. PMID: 19563409 Ref: Recommendations on current approach to gastric cancer. PMID: 19661026 |
Ref: URG11 promotes gastric cancer growth and invasion by activation of beta-catenin signalling pathway. PMID: 19413886 Ref: Randomised, non-comparative phase II study of weekly docetaxel with cisplatin and 5-fluorouracil or with capecitabine in oesophagogastric cancer: the AGITG ATTAX trial. PMID: 20068567 Ref: Surgical outcome after docetaxel-based neoadjuvant chemotherapy in locally-advanced gastric cancer. PMID: 20143466 |
Ref: Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells. PMID: 21494638 Ref: Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of beta-catenin in gastric cancer. PMID: 21750908 |
Ref: S100A6 protein negatively regulates CacyBP/SIP-mediated inhibition of gastric cancer cell proliferation and tumorigenesis. PMID: 22295074 |
Ref: FOXO6 promotes gastric cancer cell tumorigenicity via upregulation of C-myc. PMID: 23714368 Ref: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer. PMID: 23803691 |
Ref: Prolyl hydroxylase 3 inhibited the tumorigenecity of gastric cancer cells. PMID: 23533015 Ref: Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the beta-Catenin/TCF/LEF-1 pathway in gastric cancer cells. PMID: 24335145 Ref: PATHOME: an algorithm for accurately detecting differentially expressed subpathways. PMID: 24681952 Ref: HNF4A immunohistochemistry facilitates distinction between primary and metastatic breast and gastric carcinoma. PMID: 24711169 Ref: Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. PMID: 24931004 |
Ref: Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. PMID: 25053715 Ref: Intelectin 1 suppresses tumor progression and is associated with improved survival in gastric cancer. PMID: 25965823 Ref: The significance of NTR1 expression and its correlation with beta-catenin and EGFR in gastric cancer. PMID: 26215716 |
Ref: HNF4alpha is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer. PMID: 25410163 Ref: miR-30-HNF4gamma and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach. PMID: 25800782 Ref: Mutual amplification of HNF4alpha and IL-1R1 composes an inflammatory circuit in Helicobacter pylori associated gastric carcinogenesis. PMID: 26870992 Ref: The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer. PMID: 26872378 Ref: Hepatocyte nuclear factor 4alpha is required for cell differentiation and homeostasis in the adult mouse gastric epithelium. PMID: 27340127 |
Ref: HNF4A expression as a potential diagnostic tool to discriminate primary gastric cancer from breast cancer metastasis in a Brazilian cohort. PMID: 28583188 |
Ref: Gastric cancer biomarkers; A systems biology approach. PMID: 29556568 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: VGLL4 is a transcriptional cofactor acting as a novel tumor suppressor via interacting with TEADs. PMID: 30034932 |