Primary Site >> Liver Cancer
Gene >> HNF1A
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Ref: LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia. PMID: 1673925 |
Ref: Liver-specific expression of human insulin-like growth factor binding protein 1: functional role of transcription factor HNF1 in vivo. PMID: 7678342 Ref: Characterization of cis-acting elements and transacting factors involved in the tissue-specific and developmental regulation of IGFBP-1 gene expression. PMID: 7683517 |
Ref: The DNA binding activity of the liver transcription factors LFB1 (HNF1) and HNF4 varies coordinately in rat hepatocellular carcinoma. PMID: 7834800 |
Ref: Cellular factors controlling the activity of woodchuck hepatitis virus enhancer II. PMID: 8676498 Ref: trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines. PMID: 8681951 |
Ref: Bi-allelic inactivation of TCF1 in hepatic adenomas. PMID: 12355088 |
Ref: Frequent mutations of hepatocyte nuclear factor 1 in colorectal cancer with microsatellite instability. PMID: 12730871 |
Ref: Control of ACAT2 liver expression by HNF1. PMID: 15961790 |
Ref: HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation. PMID: 17379603 |
Ref: ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines. PMID: 18194454 |
Ref: Specific expression and regulation of hepassocin in the liver and down-regulation of the correlation of HNF1alpha with decreased levels of hepassocin in human hepatocellular carcinoma. PMID: 19304666 Ref: Correlation between hepatocarcinogenic effect of estragole and its influence on glucocorticoid induction of liver-specific enzymes and activities of FOXA and HNF4 transcription factors in mouse and rat liver. PMID: 19463090 Ref: Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. PMID: 19617899 |
Ref: Loss of hepatocyte nuclear factor 1alpha function in human hepatocellular adenomas leads to aberrant activation of signaling pathways involved in tumorigenesis. PMID: 20041408 Ref: Molecular genetics of hepatocellular neoplasia. PMID: 20182587 Ref: Subtype classification of hepatocellular adenoma. PMID: 20357450 Ref: [Effect of hepatocarcinogenicity of estragole on the glucocorticoid-mediated induction of liver-specific enzymes and the activity of the transcription factors FOXA and HNF4 in the liver of mouse and rat]. PMID: 20429289 |
Ref: Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management. PMID: 21339346 Ref: Revisiting the pathology of resected benign hepatocellular nodules using new immunohistochemical markers. PMID: 21344354 Ref: HNF1alpha inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines. PMID: 21975049 |
Ref: MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1alpha) in adult liver and controls expression of frizzled-6. PMID: 21887698 |
Ref: Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I. PMID: 23046672 Ref: Hepatocyte nuclear factor 1beta is a novel prognostic marker independent of the Milan criteria in transplantable hepatocellular carcinoma: a retrospective analysis based on tissue microarrays. PMID: 23203386 Ref: Hepatocellular benign tumors-from molecular classification to personalized clinical care. PMID: 23485860 Ref: Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. PMID: 23512712 Ref: Histological and immunohistochemical revision of hepatocellular adenomas: a learning experience. PMID: 23533787 Ref: Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context. PMID: 23691330 Ref: Primary hepatocellular neoplasms in a MODY3 family with a novel HNF1A germline mutation. PMID: 23707370 |
Ref: Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma. PMID: 25516669 |
Ref: Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR). PMID: 26215100 |
Ref: Liver biopsy for diagnosis of presumed benign hepatocellular lesions lacking magnetic resonance imaging diagnostic features of focal nodular hyperplasia. PMID: 26969817 Ref: Expression of liver fatty acid binding protein in hepatocellular carcinoma. PMID: 26997447 Ref: Validation of a multi-omics strategy for prioritizing personalized candidate driver genes PMID: 27469031 |
Ref: Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation. PMID: 27939373 Ref: Molecular classification of hepatocellular adenoma in clinical practice. PMID: 28733222 Ref: Hepatocyte Nuclear Factor 1alpha-Mutated Hepatocellular Adenomas: An Atypical Presentation. PMID: 29282384 Ref: Comparison of Subtypes of Hepatocellular Adenoma to Hepatocellular Carcinoma and Non-Neoplastic Liver Tissue in Terms of PTEN Expression. PMID: 29687774 |
Ref: p.Q511L mutation of HNF1alpha in hepatocellular carcinoma suppresses the transcriptional activity and the anti-tumor effect of HNF1alpha. PMID: 29101032 Ref: The HNF1alpha-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1. PMID: 29466992 Ref: Insights into the etiology-associated gene regulatory networks in hepatocellular carcinoma from The Cancer Genome Atlas. PMID: 29672926 Ref: Loss-of-function mutations in Zn-finger DNA-binding domain of HNF4A cause aberrant transcriptional regulation in liver cancer. PMID: 29899848 Ref: Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis. PMID: 29992318 Ref: Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: a retrospective analysis of data from MSK-IMPACT and TCGA. PMID: 30121369 Ref: Lower Circulating miR-122 Level in Patients with HNF1A Variant-Induced Diabetes Compared with Type 2 Diabetes. PMID: 30155490 Ref: Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4alpha. PMID: 30191603 Ref: Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors. PMID: 30220099 Ref: Molecular classification of hepatocellular adenomas: impact on clinical practice. PMID: 30302195 |