Primary Site >> Esophagus Cancer
Gene >> HIF1A
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Ref: Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. PMID: 11280732 |
Ref: Pretreatment evaluation of combined HIF-1alpha, p53 and p21 expression is a useful and sensitive indicator of response to radiation and chemotherapy in esophageal cancer. PMID: 15170665 |
Ref: Correlation of hypoxia inducible factor-1alpha with lymphatic metastasis via vascular endothelial growth factor-C in human esophageal cancer. PMID: 15713437 Ref: Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma. PMID: 15771621 Ref: Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis. PMID: 16127293 |
Ref: HIF-1alpha mRNA is not associated with histopathological regression following neoadjuvant chemoradiation in esophageal cancer. PMID: 17201171 |
Ref: Cytogenetic characterization and gene expression profiling in the rat reflux-induced esophageal tumor model. PMID: 17320581 Ref: [Expression and biological significance of HPA and HIF-1alpha in human esophageal squamous cell carcinoma]. PMID: 18246800 |
Ref: [Expression of hypoxia-inducible factor-1alpha and vessel endothelial growth factor in esophageal squamous cell carcinoma and clinico-pathological significance thereof]. PMID: 19080625 |
Ref: Clinical significance of the gene expression profile in residual tumor cells after neoadjuvant chemo-radiotherapy for esophageal cancer. PMID: 19424628 |
Ref: [Effect of fractioned irradiation on HIF-1alpha and MDR1 expression in esophageal cancer cells]. PMID: 20501388 Ref: Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells. PMID: 21220916 |
Ref: HIF-1alpha and VEGF are associated with disease progression in esophageal carcinoma. PMID: 20451923 Ref: Effects of YC-1 targeting hypoxia-inducible factor 1 alpha in oesophageal squamous carcinoma cell line Eca109 cells. PMID: 20977428 Ref: Various doses of fractioned irradiation modulates multidrug resistance 1 expression differently through hypoxia-inducible factor 1alpha in esophageal cancer cells. PMID: 21309917 Ref: Inhibition of hypoxia inducible factor 1alpha expression suppresses the progression of esophageal squamous cell carcinoma. PMID: 21519196 Ref: Clinical significance of HIF-1alpha expression in patients with esophageal cancer treated with concurrent chemoradiotherapy. PMID: 21737664 |
Ref: Assessment of stanniocalcin-1 as a prognostic marker in human esophageal squamous cell carcinoma. PMID: 22200953 Ref: Early evaluation of the apoptotic index ratio is useful in predicting the efficacy of chemoradiotherapy in esophageal squamous cell carcinoma. PMID: 22740896 Ref: HIF-1alpha contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression. PMID: 23093058 |
Ref: Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation. PMID: 22340517 Ref: Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice. PMID: 23291985 Ref: Primary tumor vascularity in esophagus cancer. CD34 and HIF1-alpha expression correlate with tumor progression. PMID: 23653235 Ref: Berberine enhances radiosensitivity of esophageal squamous cancer by targeting HIF-1alpha in vitro and in vivo. PMID: 24025355 Ref: Metastasis associated protein 1 correlates with Hypoxia inducible-factor 1 alpha expression and lymphangiogenesis in esophageal cancer. PMID: 28920244 |
Ref: Blockage of Nrf2 suppresses the migration and invasion of esophageal squamous cell carcinoma cells in hypoxic microenvironment. PMID: 24028437 Ref: [Amphotericin B suppresses migration and invasion of esophageal carcinoma Eca109 cells in hypoxic microenvironment by down-regulating hypoxia-inducible factor-1alpha activity]. PMID: 24968833 Ref: STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1alpha. PMID: 24981247 Ref: HIF-1alpha induces VE-cadherin expression and modulates vasculogenic mimicry in esophageal carcinoma cells. PMID: 25548487 |
Ref: Metformin enhances radiation response of ECa109 cells through activation of ATM and AMPK. PMID: 25661368 Ref: Upregulation of extracellular matrix metalloproteinase inducer promotes hypoxia-induced epithelial-mesenchymal transition in esophageal cancer. PMID: 26458866 Ref: Oxygen carrier YQ23 can enhance the chemotherapeutic drug responses of chemoresistant esophageal tumor xenografts. PMID: 26553104 |
Ref: Tenascin-C, a Prognostic Determinant of Esophageal Squamous Cell Carcinoma. PMID: 26731558 Ref: Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells. PMID: 27239113 Ref: VEGF expression is regulated by HIF-1alpha and ARNT in 3D KYSE-70, esophageal cancer cell spheroids. PMID: 27542820 Ref: Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinoma. PMID: 27826618 Ref: Improved sensitization effect of sunitinib in cancer cells of the esophagus under hypoxic microenviroment. PMID: 28105174 |
Ref: Expression and significance of GRHL2 in esophageal cancer. PMID: 28435293 Ref: Hypoxia inducible factor-1alpha regulates autophagy via the p27-E2F1 signaling pathway. PMID: 28627618 Ref: Hypoxia and hypoxia response-associated molecular markers in esophageal cancer: A systematic review. PMID: 28705470 |
Ref: Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo. PMID: 29290767 Ref: Brucea javanica seed oil enhances the radiosensitivity of esophageal cancer by inhibiting hypoxia-inducible factor 1alpha, in vitro and in vivo. PMID: 29456736 Ref: CAIX furthers tumour progression in the hypoxic tumour microenvironment of esophageal carcinoma and is a possible therapeutic target. PMID: 29865880 Ref: ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis. PMID: 30081903 Ref: Dihydroartemisinin Increases the Sensitivity of Photodynamic Therapy Via NF-kappaB/HIF-1alpha/VEGF Pathway in Esophageal Cancer Cell in vitro and in vivo. PMID: 30099443 Ref: Knockdown of USP28 enhances the radiosensitivity of esophageal cancer cells via the c-Myc/hypoxia-inducible factor-1 alpha pathway. PMID: 30206969 |