Primary Site >> Colorectal Cancer
Gene >> HCAR2
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Ref: p53 and HLA class-I expression are not down-regulated in colorectal cancer liver metastases. PMID: 15065606 |
Ref: GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. PMID: 19276343 |
Ref: Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. PMID: 22517765 |
Ref: The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival. PMID: 24371223 Ref: Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. PMID: 24412617 Ref: GPR109a: the missing link between microbiome and good health? PMID: 24439263 |
Ref: IFNgamma Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer. PMID: 25735954 |
Ref: The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis? PMID: 27346602 |
Ref: Effect of butyrate and Lactobacillus GG on a butyrate receptor and transporter during Campylobacter jejuni exposure. PMID: 28333199 Ref: Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma. PMID: 28358223 |