Primary Site >> Colorectal Cancer
Gene >> GZMB
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Ref: Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. PMID: 1465616 |
Ref: T cell receptor-zeta and granzyme B expression in mononuclear cell infiltrates in normal colon mucosa and colon carcinoma. PMID: 9155587 |
Ref: CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. PMID: 9721846 |
Ref: The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells. PMID: 11825663 |
Ref: Effector memory T cells, early metastasis, and survival in colorectal cancer. PMID: 16371631 |
Ref: Characterization of tumour-infiltrating lymphocytes and apoptosis in colitis-associated neoplasia: comparison with sporadic colorectal cancer. PMID: 16315333 Ref: Gene expression analysis of tumor infiltrating lymphocyte markers in endometrial cancers indicates no significant increases in those cases with microsatellite instability. PMID: 17192060 |
Ref: Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors. PMID: 17460060 |
Ref: High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas. PMID: 17965063 Ref: Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. PMID: 18307280 Ref: The specific immune response to tumor antigen CP1 and its correlation with improved survival in colon cancer patients. PMID: 18395081 Ref: Primary CD56+ NK/T-cell lymphoma of the rectum accompanied with refractory ulcerative colitis. PMID: 18648746 |
Ref: Comparison of caspase genes for the induction of apoptosis following gene delivery. PMID: 19067254 Ref: The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy. PMID: 19226101 Ref: Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas. PMID: 19527492 Ref: Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors. PMID: 20014453 |
Ref: Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients. PMID: 20385003 Ref: Quantification of prognostic immune cell markers in colorectal cancer using whole slide imaging tumor maps. PMID: 21456345 |
Ref: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. PMID: 21303976 Ref: Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy. PMID: 21846824 |
Ref: Infiltration of Lynch colorectal cancers by activated immune cells associates with early staging of the primary tumor and absence of lymph node metastases. PMID: 22261803 Ref: Sequential metastases of colorectal cancer: Immunophenotypes and spatial distributions of infiltrating immune cells in relation to time and treatments. PMID: 22934251 |
Ref: The effect of phloretin on human gammadelta T cells killing colon cancer SW-1116 cells. PMID: 23174508 Ref: Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer. PMID: 24138752 |
Ref: Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma. PMID: 24803811 Ref: Granzyme B gene polymorphisms, colorectal cancer risk, and metastasis. PMID: 25313744 |
Ref: Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration. PMID: 25671296 Ref: Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-gamma. PMID: 26297765 Ref: Absence of myeloperoxidase and CD8 positive cells in colorectal cancer infiltrates identifies patients with severe prognosis. PMID: 26587320 |
Ref: Abdominal Infection Suppresses the Number and Activity of Intrahepatic Natural Killer Cells and Promotes Tumor Growth in a Murine Liver Metastasis Model. PMID: 25752891 Ref: Targeted intracellular protein delivery based on hyaluronic acid-green tea catechin nanogels. PMID: 26785145 Ref: Decreased Anti-Tumor Cytotoxic Immunity among Microsatellite-Stable Colon Cancers from African Americans. PMID: 27310868 Ref: Gp96-Ig/Costimulator (OX40L, ICOSL, or 4-1BBL) Combination Vaccine Improves T-cell Priming and Enhances Immunity, Memory, and Tumor Elimination. PMID: 27364122 Ref: Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer. PMID: 27517754 Ref: CD169 identifies an activated CD8(+) T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients. PMID: 27622027 |
Ref: T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. PMID: 27935860 Ref: Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women. PMID: 27979806 Ref: Deficiency of the immunostimulatory cytokine IL-21 promotes intestinal neoplasia via dysregulation of the Th1/Th17 axis. PMID: 28197386 Ref: Digital analysis and epigenetic regulation of the signature of rejection in colorectal cancer. PMID: 28507795 Ref: Tumor location impacts immune response in mouse models of colon cancer. PMID: 28903381 |
Ref: Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies with MVA-betaGal and MVA-MUC1 (TG4010) in a murine tumor model. PMID: 28925793 Ref: Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human gammadeltaT cells against colon cancer. PMID: 29104081 Ref: Neoadjuvant radiochemotherapy decreases the total amount of tumor infiltrating lymphocytes, but increases the number of CD8+/Granzyme B+ (GrzB) cytotoxic T-cells in rectal cancer. PMID: 29308324 Ref: CD8(+)CXCR5(+) T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer. PMID: 29544815 Ref: Functional activity of natural killer cells in biological fluids in patients with colorectal and ovarian cancers. PMID: 29736145 Ref: The Impact of Immune Interaction on the Metastatic Infiltration of Colorectal Carcinoma to Lymph Nodes. PMID: 29970545 Ref: Stromal cell PD-L1 inhibits CD8+ T-cell antitumor immune responses and promotes colon cancer. PMID: 30228206 |