Primary Site >> Pancreatic Cancer
Gene >> GRP
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Ref: [Gut hormones with activity to modulate cellular growth]. PMID: 2083220 Ref: Effects of neuromedin B and GRP-10 on gastrin and insulin release from cultured tumor cells of a malignant gastrinoma. PMID: 2101791 |
Ref: Gastrin-releasing peptide: in vivo and in vitro growth effects on an acinar pancreatic carcinoma. PMID: 1319829 |
Ref: Effect of gastrin-releasing peptide on the pancreatic tumor cell line (Capan). PMID: 8280369 |
Ref: Inhibitory effect of bombesin receptor antagonist RC-3095 on the growth of human pancreatic cancer cells in vivo and in vitro. PMID: 8313359 |
Ref: New pseudononapeptide bombesin antagonists with C-terminal leu-psi(ch2n)tac-nh2 show high binding-affinity to bombesin/grp receptors on cfpac-1 human pancreatic-cancer cells. PMID: 21556653 |
Ref: Expression and characterization of gastrin-releasing peptide receptor in normal and cancerous pancreas. PMID: 8927617 Ref: Effects of new bombesin antagonists given singly or in combination with a somatostatin analog on nitrosamine-induced pancreatic cancers in hamsters. PMID: 21541526 |
Ref: Design, synthesis, and in vitro evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin. PMID: 9012839 |
Ref: Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma. PMID: 9650851 |
Ref: Growth inhibition of experimental pancreatic cancers and sustained reduction in epidermal growth factor receptors during therapy with hormonal peptide analogs. PMID: 10480336 |
Ref: Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions. PMID: 11286473 |
Ref: Preclinical comparison of (111)In-labeled DTPA- or DOTA-bombesin analogs for receptor-targeted scintigraphy and radionuclide therapy. PMID: 12468515 |
Ref: Radiochemical investigations of (99m)Tc-N(3)S-X-BBN[7-14]NH(2): an in vitro/in vivo structure-activity relationship study where X = 0-, 3-, 5-, 8-, and 11-carbon tethering moieties. PMID: 12526698 Ref: Radiochemical investigations of 177Lu-DOTA-8-Aoc-BBN[7-14]NH2: an in vitro/in vivo assessment of the targeting ability of this new radiopharmaceutical for PC-3 human prostate cancer cells. PMID: 12623108 Ref: Radiochemical investigations of [188Re(H2O)(CO)3-diaminopropionic acid-SSS-bombesin(7-14)NH2]: syntheses, radiolabeling and in vitro/in vivo GRP receptor targeting studies. PMID: 12680195 Ref: Novel series of 111In-labeled bombesin analogs as potential radiopharmaceuticals for specific targeting of gastrin-releasing peptide receptors expressed on human prostate cancer cells. PMID: 12732685 Ref: Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2 PMID: 12874010 |
Ref: Gastrin-releasing peptide (GRP) analogues for cancer imaging. PMID: 15186603 Ref: A small cell carcinoma of the pancreas with a high level of serum ProGRP. PMID: 15365423 Ref: Alexa Fluor 680-glycylglycylglycine-bombesin[7-14]NH2 peptide PMID: 20641271 Ref: (99m)Tc-Ethylenenediamine-N,N'-diacetic acid/hydrazinonicotinamide[Lys(3)]-bombesin PMID: 20641296 Ref: [(18)F]Fluorobenzyl-PEG3-Glu-c(RGDyK)-bombesin[7-14] PMID: 20641311 Ref: [(111)In-Diethylenetriamine pentaacetic acid-ACMpip(5),Tha(6),betaAla(11),Tha(13),NIe(14)]bombesin(5-14) PMID: 20641369 Ref: [(111)In-Diethylenetriaminepentaacetic acid-Pro(1),Tyr(4)]bombesin PMID: 20641503 Ref: (111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 PMID: 20641535 Ref: [(111)In-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-Pro(1),Tyr(4)]Bombesin PMID: 20641605 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] PMID: 20641630 Ref: (99m)Tc-(Hydrazinonicotinic acid-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2)(tricine)(TPPTS) PMID: 20641678 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetate-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 20641703 Ref: (68)Ga-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] PMID: 20641746 Ref: (86)Y-DOTA-[Pro(1),Tyr(4)]-Bombesin[1-14] PMID: 20641773 Ref: (64)Cu-DOTA-[Pro(1),Tyr(4)]-Bombesin[1-14] PMID: 20641835 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 20641895 Ref: [(18)F]Fluorobenzyl-bombesin[7-14]-c(RGDyK) PMID: 20641919 Ref: Bombesin peptide conjugated-cross-linked iron oxide-Cy5.5 PMID: 20641922 Ref: (99m)Tc identical withNitrido(diphosphine)-Cys-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 20641947 Ref: (111)In-Diethylenetriamine pentaacetic acid-QKYGNQWAVGHLM-NH2 PMID: 20642008 Ref: (68)Ga-DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta- Leu-NH2 PMID: 21563331 Ref: (111)In-DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta -Leu-NH2 PMID: 21563332 Ref: 3-Cyano-4-[(18)F]fluoro-benzoyl-Ala(SO3H)-Ala(SO3H)-Ava-Gln-Trp-Ala-Val-NMeGly-Hi s-Sta-Leu-NH2 PMID: 21882401 Ref: (68)Ga-1,4,7-Triazacyclononane-1,4-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 23057095 Ref: (111)In-1,4,7,10-Tetraazacyclododecane-1,4,7,10-triacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 23057096 Ref: Al(18)F-1,4,7-Triazacyclononane-1,4,7-diacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 PMID: 23057097 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4-diacetic acid-c(RGDyK)-Glu-6-aminohexanoic acid-bombesin[7-14]NH2 PMID: 23166957 Ref: (99m)Tc-Hydrazinonicotinyl(tricine)(TPPTS)-Glu-c(RGDyK)-bombesin[7-14]NH2 PMID: 23166958 |
Ref: GRP receptor-targeted PET of a rat pancreas carcinoma xenograft in nude mice with a 68Ga-labeled bombesin(6-14) analog. PMID: 15809493 Ref: Inhibition of growth of experimental human and hamster pancreatic cancers in vivo by a targeted cytotoxic bombesin analog. PMID: 16163060 |
Ref: In vitro and in vivo evaluation of Alexa Fluor 680-bombesin[7-14]NH2 peptide conjugate, a high-affinity fluorescent probe with high selectivity for the gastrin-releasing peptide receptor. PMID: 17532883 Ref: Radiolabeling of bombesin-like peptide with 99mTc: 99mTc-litorin and biodistribution in rats. PMID: 17760415 |
Ref: Targeted imaging of gastrin-releasing peptide receptors with 99mTc-EDDA/HYNIC-[Lys3]-bombesin: biokinetics and dosimetry in women. PMID: 18753829 |
Ref: In vitro and in vivo metabolism of Lu-AMBA, a GRP-receptor binding compound, and the synthesis and characterization of its metabolites. PMID: 19480415 Ref: Structural assessment and biological evaluation of two N3S bombesin derivatives. PMID: 19522464 |
Ref: Use of analogs of peptide hormones conjugated to cytotoxic radicals for chemotherapy targeted to receptors on tumors. PMID: 21034424 |
Ref: Evaluation of (99m)Tc-HYNIC-betaAla-Bombesin(7-14) as an agent for pancreas tumor detection in mice. PMID: 26445336 |
Ref: Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. PMID: 29422604 |