Primary Site >> Liver Cancer
Gene >> GNMT
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Ref: Effect of dietary methyl group deficiency on one-carbon metabolism in rats. PMID: 2703919 |
Ref: Characterization of glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma. PMID: 9495250 |
Ref: Genomic structure, expression, and chromosomal localization of the human glycine N-methyltransferase gene. PMID: 10843803 |
Ref: Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer. PMID: 12566309 Ref: Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies. PMID: 12566990 |
Ref: Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway. PMID: 15150120 |
Ref: Benzo[a]pyrene and glycine N-methyltransferse interactions: gene expression profiles of the liver detoxification pathway. PMID: 16545412 |
Ref: Haplotypes, loss of heterozygosity, and expression levels of glycine N-methyltransferase in prostate cancer. PMID: 17332283 |
Ref: Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice. PMID: 18318442 Ref: Glycine N-methyltransferase is a favorable prognostic marker for human cholangiocarcinoma. PMID: 18624901 Ref: S-adenosylmethionine and proliferation: new pathways, new targets. PMID: 18793149 |
Ref: Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility. PMID: 19035462 Ref: Hepatocellular carcinoma in GNMT-/- mice. PMID: 19345238 Ref: Characterization of the 5' regulatory region of the human Glycine N-methyltransferase gene. PMID: 19439180 |
Ref: Benzo(a)pyrene induced glycine N-methyltransferase messenger RNA expression in Fundulus heteroclitus embryos. PMID: 19892394 Ref: Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver. PMID: 21137059 |
Ref: Higher susceptibility to aflatoxin B(1)-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice. PMID: 20473876 Ref: Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis. PMID: 21145824 Ref: Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation. PMID: 21411609 |
Ref: Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma. PMID: 22160218 Ref: Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis. PMID: 22183894 Ref: Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase. PMID: 22392635 Ref: An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis. PMID: 22434528 Ref: Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1. PMID: 22687285 Ref: S-adenosylmethionine in liver health, injury, and cancer. PMID: 23073625 |
Ref: The multi-functional roles of GNMT in toxicology and cancer. PMID: 23147572 Ref: A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma. PMID: 23475283 Ref: Identification of FKBP11 as a biomarker for hepatocellular carcinoma. PMID: 23749938 |
Ref: A novel role of the tumor suppressor GNMT in cellular defense against DNA damage. PMID: 23922098 |
Ref: TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency. PMID: 25531568 Ref: Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis. PMID: 25535034 |
Ref: Identification of 1,2,3,4,6-Penta-O-galloyl-beta-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma. PMID: 27153064 Ref: Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver. PMID: 27716281 |
Ref: Characterization of the GNMT-HectH9-PREX2 tripartite relationship in the pathogenesis of hepatocellular carcinoma. PMID: 28205209 |
Ref: Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. PMID: 29891549 Ref: MicroRNA-224 down-regulates Glycine N-methyltransferase gene expression in Hepatocellular Carcinoma. PMID: 30115977 Ref: Signature molecules expressed differentially in a liver disease stage-specific manner by HIV-1 and HCV co-infection. PMID: 30138348 Ref: AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage. PMID: 30217986 Ref: MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis. PMID: 30237481 |