Primary Site >> Pancreatic Cancer

Gene >> GNAS

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Ref: A pituitary specific point mutation of codon 201 of the Gs alpha gene in a pituitary adenoma of a patient with multiple endocrine neoplasia (MEN) type 1.
PMID: 1358601
Ref: Neuroendocrine secretory protein-55 (NESP-55) expression discriminates pancreatic endocrine tumors and pheochromocytomas from gastrointestinal and pulmonary carcinoids.
PMID: 15371954
Ref: Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts.
PMID: 22859495
Ref: Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms.
PMID: 23403822
Ref: Classification, morphology and molecular pathology of premalignant lesions of the pancreas.
PMID: 23442735
Ref: BCL10 as a useful marker for pancreatic acinar cell carcinoma, especially using endoscopic ultrasound cytology specimens.
PMID: 23530562
Ref: Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype.
PMID: 23532108
Ref: Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.
PMID: 23846778
Ref: [Will molecular diagnostics become established in pancreatic pathology?].
PMID: 24196616
Ref: Genes-environment interactions in obesity- and diabetes-associated pancreatic cancer: a GWAS data analysis.
PMID: 24136929
Ref: Whole-exome sequencing of pancreatic neoplasms with acinar differentiation.
PMID: 24293293
Ref: Molecular genetics of pancreatic neoplasms and their morphologic correlates: an update on recent advances and potential diagnostic applications.
PMID: 24436263
Ref: Case report: Intraductal tubulopapillary neoplasm of the pancreas with unique clear cell phenotype.
PMID: 24443801
Ref: Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.
PMID: 24604757
Ref: Intraductal neoplasms of the pancreas.
PMID: 25282472
Ref: Mutant KRAS and GNAS DNA Concentrations in Secretin-Stimulated Pancreatic Fluid Collected from the Pancreatic Duct and the Duodenal Lumen.
PMID: 25393586
Ref: Differential expression of GNAS and KRAS mutations in pancreatic cysts.
PMID: 25435574
Ref: Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas.
PMID: 25081753
Ref: Activating mutations of GNAS and KRAS in cystic fluid can help detect intraductal papillary mucinous neoplasms of the pancreas.
PMID: 25656048
Ref: GNAS mutation is a frequent event in pancreatic intraductal papillary mucinous neoplasms and associated adenocarcinomas.
PMID: 25796395
Ref: Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
PMID: 26087898
Ref: A combination of molecular markers and clinical features improve the classification of pancreatic cysts.
PMID: 26253305
Ref: A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
PMID: 26559377
Ref: A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?
PMID: 26586167
Ref: Intraductal tubulopapillary neoplasm of the bile duct: A case report and review of the published work.
PMID: 26459784
Ref: Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia.
PMID: 26626780
Ref: Tracking the Clonal Evolution of Adenosquamous Carcinoma, a Rare Variant of Intraductal Papillary Mucinous Neoplasm of the Pancreas.
PMID: 27295533
Ref: Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas.
PMID: 27343369
Ref: EUS for pancreatic cystic neoplasms: The roadmap to the future is much more than just a few shades of gray.
PMID: 27955751
Ref: Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video).
PMID: 28259593
Ref: Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis.
PMID: 28280620
Ref: Integrated clinicopathological features and gene microarray analysis of pancreatic neuroendocrine tumors.
PMID: 28479381
Ref: Cross-sectional prevalence of pancreatic cystic lesions in patients with acromegaly, a single-center experience.
PMID: 28540626
Ref: [Resection of main duct and mixed type IPMN >/=5 mm].
PMID: 28842734
Ref: GNAS shifts metabolism in pancreatic cancer.
PMID: 29941928
Ref: Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
PMID: 29941929
Ref: Intrapancreatic recurrence of intraductal tubulopapillary neoplasm (ITPN) 16 years after the initial surgery for noninvasive ITPN: a case report.
PMID: 30116990