Primary Site >> Stomach Cancer
Gene >> GKN2
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Ref: [Down-regulated full-length novel gene GDDR and its effect on gastric cancer]. PMID: 12921637 |
Ref: [Study on novel gene GDDR related to gastric cancer]. PMID: 15774165 Ref: Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C. PMID: 15924415 |
Ref: Cytokine regulation of the trefoil factor family binding protein GKN2 (GDDR/TFIZ1/blottin) in human gastrointestinal epithelial cells. PMID: 17595528 |
Ref: Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis. PMID: 18593995 |
Ref: The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer. PMID: 18722547 |
Ref: A novel gastrokine, Gkn3, marks gastric atrophy and shows evidence of adaptive gene loss in humans. PMID: 20138039 Ref: Detection of beta-catenin, gastrokine-2 and embryonic stem cell expressed ras in gastric cancers. PMID: 21151392 |
Ref: Gastrointestinal tract specific gene GDDR inhibits the progression of gastric cancer in a TFF1 dependent manner. PMID: 21870107 |
Ref: Gastrokines: stomach-specific proteins with putative homeostatic and tumor suppressor roles. PMID: 23154977 |
Ref: GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity. PMID: 24151046 Ref: Exploring the proteomic landscape of a gastric cancer biopsy with the shotgun imaging analyzer. PMID: 24283986 Ref: Gastrokine-2 is downregulated in gastric cancer and its restoration suppresses gastric tumorigenesis and cancer metastasis. PMID: 24408014 Ref: EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells. PMID: 24460791 Ref: [Expression and clinical significance of gastric dramatic down-related gene in gastric cancer and precancerous lesions]. PMID: 24606753 |
Ref: Trophoblast expression dynamics of the tumor suppressor gene gastrokine 2. PMID: 26070363 |
Ref: A possible role of GDDR in the development of Helicobacter pylori-associated gastric cancer. PMID: 26842925 Ref: Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression. PMID: 26974160 Ref: Gastrointestinal Factor GDDR Attenuates Epithelial-Mesenchymal Transition in Gastric Cancer via Inhibiting AKT Signal. PMID: 27017226 Ref: Gastrokine-2 suppresses epithelial mesenchymal transition through PI3K/AKT/GSK3beta signaling in gastric cancer. PMID: 27323966 |
Ref: Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells. PMID: 28150071 Ref: GKN2 increases apoptosis, reduces the proliferation and invasion ability of gastric cancer cells through down-regulating the JAK/STAT signaling pathway. PMID: 28337309 Ref: Global transcriptomewide analysis of the function of GDDR in acute gastric lesions. PMID: 28990076 |