Primary Site >> Stomach Cancer
Gene >> GKN1
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Gastrokine 1 is abundantly and specifically expressed in superficial gastric epithelium, down-regulated in gastric carcinoma, and shows high evolutionary conservation. PMID: 15221938 |
Ref: Proteomic alteration in gastic adenocarcinomas from Japanese patients. PMID: 17187689 |
Ref: Gastrokine 1 expression in patients with and without Helicobacter pylori infection. PMID: 17092786 Ref: Cytokine regulation of the trefoil factor family binding protein GKN2 (GDDR/TFIZ1/blottin) in human gastrointestinal epithelial cells. PMID: 17595528 |
Ref: Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis. PMID: 18593995 Ref: Molecular expression of Gastrokine 1 in normal mucosa and in Helicobacter pylori-related preneoplastic and neoplastic gastric lesions. PMID: 18927498 Ref: Biochemical properties of gastrokine-1 purified from chicken gizzard smooth muscle. PMID: 19057650 |
Ref: A novel gastrokine, Gkn3, marks gastric atrophy and shows evidence of adaptive gene loss in humans. PMID: 20138039 |
Ref: Inactivation of the Gastrokine 1 gene in gastric adenomas and carcinomas. PMID: 21341273 Ref: Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells. PMID: 21751384 Ref: Overexpression of gastrokine 1 in gastric cancer cells induces Fas-mediated apoptosis. PMID: 21792914 Ref: Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. PMID: 21898090 |
Ref: Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells. PMID: 21676900 Ref: Proteomic analysis of gastric cancer and immunoblot validation of potential biomarkers. PMID: 22468085 Ref: Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis. PMID: 22621392 Ref: Role of trefoil factor 1 in gastric cancer and relationship between trefoil factor 1 and gastrokine 1. PMID: 22842654 Ref: Relationship between expression of gastrokine 1 and clinicopathological characteristics in gastric cancer patients. PMID: 23317277 |
Ref: Structural characterization and biological properties of human gastrokine 1. PMID: 23319233 Ref: Gastrokine 1 regulates NF-kappaB signaling pathway and cytokine expression in gastric cancers. PMID: 23444260 Ref: GKN1-miR-185-DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle. PMID: 23846337 Ref: The tumor suppressor gastrokine-1 is expressed in placenta and contributes to the regulation of trophoblast migration. PMID: 23993393 Ref: Functional analysis of the NH2-terminal hydrophobic region and BRICHOS domain of GKN1. PMID: 24099765 |
Ref: Aberrant expression of SOX9 is associated with gastrokine 1 inactivation in gastric cancers. PMID: 23812904 Ref: GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity. PMID: 24151046 Ref: Lipid hydroperoxide-derived modification of proteins in gastrointestinal tract. PMID: 24374925 Ref: Discovery of tumor markers for gastric cancer by proteomics. PMID: 24404153 Ref: EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells. PMID: 24460791 Ref: Anti-amyloidogenic property of human gastrokine 1. PMID: 25139219 Ref: The role of gastrokine 1 in gastric cancer. PMID: 25328759 Ref: Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer. PMID: 25344918 Ref: Decreased expression of gastrokine 1 in gastric mucosa of gastric cancer patients. PMID: 25469040 |
Ref: GKN1 inhibits cell invasion in gastric cancer by inactivating the NF-kappaB pathway. PMID: 25725220 Ref: Ectopic expression of gastrokine 1 in gastric cancer cells up-regulates tight and adherens junction proteins network. PMID: 26008777 Ref: Trophoblast expression dynamics of the tumor suppressor gene gastrokine 2. PMID: 26070363 Ref: NKX6.3 controls gastric differentiation and tumorigenesis. PMID: 26314965 |
Ref: Gastrokine 1 inhibits gastrin-induced cell proliferation. PMID: 25752269 Ref: AMP18 interacts with the anion exchanger SLC26A3 and enhances its expression in gastric cancer cells. PMID: 26700142 Ref: Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer. PMID: 27452910 Ref: The E3 ligase UBR5 regulates gastric cancer cell growth by destabilizing the tumor suppressor GKN1. PMID: 27590582 |
Ref: Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression. PMID: 27250838 Ref: Epigenetic alterations of gastrokine 1 gene expression in gastric cancer. PMID: 28129645 Ref: Role of human GKN1 on APP processing in gastric cancer. PMID: 28214529 |
Ref: Identification of significant biomarkers and pathways associated with gastric carcinogenesis by whole genome-wide expression profiling analysis. PMID: 29328368 Ref: Gastrokine 1 protein is a potential theragnostic target for gastric cancer. PMID: 29704153 |