Primary Site >> Colorectal Cancer
Gene >> FOXP3
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Ref: In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer. PMID: 17166272 Ref: Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation. PMID: 17189420 Ref: CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PMID: 17205133 |
Ref: Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. PMID: 17210703 Ref: A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy. PMID: 17289891 Ref: Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients. PMID: 17388261 Ref: Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine. PMID: 17440723 Ref: The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer. PMID: 17566017 Ref: Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma. PMID: 17724375 Ref: [Anticancer immunotherapy using inactivated Sendai virus particles]. PMID: 18040151 Ref: Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival. PMID: 18047662 |
Ref: Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner. PMID: 17962941 Ref: High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas. PMID: 17965063 Ref: Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. PMID: 18307280 Ref: Foxp3 expression in human cancer cells. PMID: 18430198 Ref: Foxp3 and microsatellite stability phenotype in colorectal cancer. PMID: 18477674 Ref: Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients. PMID: 18547033 Ref: Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. PMID: 18567620 Ref: T-cell responses to survivin in cancer patients undergoing radiation therapy. PMID: 18676762 Ref: Cytotoxic-T-lymphocyte-associated antigen 4 blockade abrogates protection by regulatory T cells in a mouse model of microbially induced innate immune-driven colitis. PMID: 18824539 Ref: High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability. PMID: 18985040 |
Ref: High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. PMID: 18825388 Ref: Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue. PMID: 19022917 Ref: Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. PMID: 19064967 Ref: Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. PMID: 19147574 Ref: T cell-mediated immunoregulation in the gastrointestinal tract. PMID: 19210347 Ref: FOXP3 defines regulatory T cells in human tumor and autoimmune disease. PMID: 19383912 Ref: Regulatory T cells actively infiltrate metastatic brain tumors. PMID: 19424570 Ref: Critical role for CD8+FoxP3+ regulatory T cells in colon cancer immune response in humans. PMID: 19433592 Ref: Antibody-mediated FOXP3 protein therapy induces apoptosis in cancer cells in vitro and inhibits metastasis in vivo. PMID: 19513564 Ref: Regulatory (FOXP3+) T cells as target for immune therapy of cervical intraepithelial neoplasia and cervical cancer. PMID: 19514119 Ref: Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. PMID: 19577568 Ref: Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. PMID: 19737943 Ref: Ineffective vaccination against solid tumors can be enhanced by hematopoietic cell transplantation. PMID: 19890041 Ref: A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice. PMID: 19920110 Ref: Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors. PMID: 20014453 |
Ref: High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients. PMID: 19856313 Ref: Intratumoral CD8(+) T/FOXP3 (+) cell ratio is a predictive marker for survival in patients with colorectal cancer. PMID: 19908042 Ref: Foxp3 expression in p53-dependent DNA damage responses. PMID: 20075077 Ref: Evaluation of immunological escape mechanisms in a mouse model of colorectal liver metastases. PMID: 20205946 Ref: Low Foxp3 expression in negative sentinel lymph nodes is associated with node metastases in colorectal cancer. PMID: 20207654 Ref: Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy. PMID: 20386463 Ref: Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals. PMID: 20460483 Ref: Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8. PMID: 20515950 Ref: Risk factors. CD8+:FOXP3+ cell ratio is a novel survival marker for colorectal cancer. PMID: 20527684 Ref: Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients. PMID: 20591136 Ref: Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles. PMID: 20664940 Ref: Clinical impact of tumor-infiltrating lymphocytes for survival in stage II colon cancer. PMID: 20665489 Ref: Accumulation of foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients. PMID: 20682706 Ref: The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis. PMID: 20706593 Ref: Dietary fish oil alters T lymphocyte cell populations and exacerbates disease in a mouse model of inflammatory colitis. PMID: 20798218 Ref: [Influence of FOLFOX regimen on the immunologic function in patients with advanced colorectal cancer]. PMID: 20878571 Ref: Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review. PMID: 20927778 Ref: TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer. PMID: 21179245 Ref: [Immunoregulatory effects of PSK on the Th1/Th2 balance and regulatory T-cells in patients with colorectal cancer]. PMID: 21224532 |
Ref: Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer. PMID: 20952660 Ref: CD103 is a hallmark of tumor-infiltrating regulatory T cells. PMID: 21207371 Ref: T-regulatory lymphocytes in peripheral blood of gastric and colorectal cancer patients. PMID: 21253393 Ref: Colorectal cancer-derived Foxp3(+) IL-17(+) T cells suppress tumour-specific CD8+ T cells. PMID: 21352252 Ref: IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer. PMID: 21357259 Ref: Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells. PMID: 21376048 Ref: IL-23/IL-23R: potential mediator of intestinal tumor progression from adenomatous polyps to colorectal carcinoma. PMID: 21547355 Ref: Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PMID: 21559338 Ref: Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. PMID: 21576350 Ref: Dendritic cell and macrophage infiltration in microsatellite-unstable and microsatellite-stable colorectal cancer. PMID: 21598004 Ref: Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer. PMID: 21644034 Ref: SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer. PMID: 21818290 Ref: Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy. PMID: 21846824 Ref: T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer. PMID: 21864372 Ref: Low expression of Granzyme B in colorectal cancer is associated with signs of early metastastic invasion. PMID: 21884199 Ref: Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3. PMID: 21904560 Ref: Behavior of circulating CD4+CD25+Foxp3+ regulatory T cells in colon cancer patients undergoing surgery. PMID: 21915633 Ref: Not so lonely at the top for cancer stem cells. PMID: 21982226 Ref: Characterization of the immunological microenvironment of tumour buds and its impact on prognosis in mismatch repair-proficient and -deficient colorectal cancers. PMID: 22034888 Ref: Impact of chemotherapy for colorectal cancer on regulatory T-cells and tumor immunity. PMID: 22199332 Ref: Augmentation of regulatory T cells (CD4+CD25+Foxp3+) correlates with tumor stage in patients with colorectal cancer. PMID: 22220406 |
Ref: Administration of 6-gingerol greatly enhances the number of tumor-infiltrating lymphocytes in murine tumors. PMID: 21792901 Ref: The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer. PMID: 21945823 Ref: Chronic psychosocial stress increases the risk for inflammation-related colon carcinogenesis in male mice. PMID: 22044139 Ref: Tumor infiltration by T lymphocytes expressing chemokine receptor 7 (CCR7) is predictive of favorable outcome in patients with advanced colorectal carcinoma. PMID: 22142823 Ref: Suppression of tumour-specific CD4(+) T cells by regulatory T cells is associated with progression of human colorectal cancer. PMID: 22207629 Ref: In vivo expansion of naive CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. PMID: 22276195 Ref: Accumulation of CCR4(+)CTLA-4 FOXP3(+)CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells. PMID: 22319577 Ref: B7-H1 expression is associated with expansion of regulatory T cells in colorectal carcinoma. PMID: 22408358 Ref: What are regulatory T cells (Treg) regulating in cancer and why? PMID: 22465232 Ref: In vitro selective depletion of CD4(+)CD25(+) regulatory T-cells from PBMC using anti-tac-SAP. PMID: 22506556 Ref: The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature. PMID: 22510350 Ref: Circulating regulatory T cells of cancer patients receiving radiochemotherapy may be useful to individualize cancer treatment. PMID: 22682747 Ref: Prognostic impact of beta-2-microglobulin expression in colorectal cancers stratified by mismatch repair status. PMID: 22859396 Ref: Prognostic impact of FoxP3+ regulatory T cells in relation to CD8+ T lymphocyte density in human colon carcinomas. PMID: 22879926 Ref: Sequential metastases of colorectal cancer: Immunophenotypes and spatial distributions of infiltrating immune cells in relation to time and treatments. PMID: 22934251 Ref: T cell subsets and colorectal cancer: discerning the good from the bad. PMID: 23041206 Ref: [K-ras mutational status and tumour-infiltrating lymphocytes in human colon cancer: state of the art and future perspectives]. PMID: 23153426 Ref: Regulatory T cells in inflammatory bowel diseases and colorectal cancer. PMID: 23155308 Ref: Treg cells in cancer: a case of multiple personality disorder. PMID: 23241741 Ref: Expression of RORgammat marks a pathogenic regulatory T cell subset in human colon cancer. PMID: 23241743 Ref: Role of nuclear receptor NR4A2 in gastrointestinal inflammation and cancers. PMID: 23322982 |
Ref: FoxP3- and CD8-positive Infiltrating Immune Cells Together Determine Clinical Outcome in Colorectal Cancer. PMID: 21732187 Ref: Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer. PMID: 22907255 Ref: Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer. PMID: 22911397 Ref: Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo. PMID: 22926062 Ref: Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Galphai2-deficient mouse. PMID: 22962436 Ref: Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. PMID: 23002055 Ref: Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases. PMID: 23010736 Ref: Intratumoral FOXP3+VEGFR2+ regulatory T cells are predictive markers for recurrence and survival in patients with colorectal cancer. PMID: 23202541 Ref: Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer. PMID: 23382847 Ref: Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer. PMID: 23390011 Ref: Tim-3 expression defines regulatory T cells in human tumors. PMID: 23526963 Ref: Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers. PMID: 23613769 Ref: Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. PMID: 23633484 Ref: Myeloid TGF-beta signaling contributes to colitis-associated tumorigenesis in mice. PMID: 23695722 Ref: The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer. PMID: 23773923 Ref: Digital pattern recognition-based image analysis quantifies immune infiltrates in distinct tissue regions of colorectal cancer and identifies a metastatic phenotype. PMID: 23963148 Ref: The appearance of Tregs in cancer nest is a promising independent risk factor in colon cancer. PMID: 24005418 Ref: Detailed analysis of inflammatory cell infiltration in colorectal cancer. PMID: 24008661 Ref: The in situ local immune response, tumour senescence and proliferation in colorectal cancer. PMID: 24022192 Ref: Potential role of plasmacytoid dendritic cells for FOXP3+ regulatory T cell development in human colorectal cancer and tumor draining lymph node. PMID: 24080284 Ref: Progressive Increase of Regulatory T Cells and Decrease of CD8+ T Cells and CD8+ T Cells/Regulatory T Cells Ratio during Colorectal Cancer Development. PMID: 24255632 Ref: Escalating regulation of 5T4-specific IFN-gamma(+) CD4(+) T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy. PMID: 24409450 Ref: In situ analysis of FOXP3(+) regulatory T cells and myeloid dendritic cells in human colorectal cancer tissue and tumor-draining lymph node. PMID: 24648920 |
Ref: Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(-) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells. PMID: 24064667 Ref: The clinical utility of the local inflammatory response in colorectal cancer. PMID: 24103145 Ref: Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patients. PMID: 24196788 Ref: FoxP3 demethylation is increased in human colorectal cancer and rat cholangiocarcinoma tissue. PMID: 24291052 Ref: Intratumoral regulatory T cells are associated with suppression of colorectal carcinoma metastasis after resection through overcoming IL-17 producing T cells. PMID: 24487033 Ref: Tumour-infiltrating inflammation and prognosis in colorectal cancer: systematic review and meta-analysis. PMID: 24504370 Ref: CD8+ and FOXP3+ tumor-infiltrating T cells before and after chemoradiotherapy for rectal cancer. PMID: 24566864 Ref: The intratumoural subsite and relation of CD8(+) and FOXP3(+) T lymphocytes in colorectal cancer provide important prognostic clues. PMID: 24675384 Ref: CD4CD8alphaalpha lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease. PMID: 24714093 Ref: Altered chemokine production and accumulation of regulatory T cells in intestinal adenomas of APC(Min/+) mice. PMID: 24777614 Ref: Peripheral Foxp3+ regulatory T cells and natural killer group 2, member D expression levels in natural killer cells of patients with colorectal cancer. PMID: 24819058 Ref: Prognostic value of tumor-infiltrating FoxP3+ T cells in gastrointestinal cancers: a meta analysis. PMID: 24827118 Ref: TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells. PMID: 24830413 Ref: Exercise effects on polyp burden and immune markers in the ApcMin/+ mouse model of intestinal tumorigenesis. PMID: 24859893 Ref: Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancer. PMID: 24906621 Ref: Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival. PMID: 24938080 Ref: Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: a retrospective cohort study. PMID: 24997850 Ref: The effect of immune microenvironment on the progression and prognosis of colorectal cancer. PMID: 25034363 Ref: B7-H1 and B7-H4 expression in colorectal carcinoma: correlation with tumor FOXP3(+) regulatory T-cell infiltration. PMID: 25053455 Ref: Characterization of an adaptive immune response in microsatellite-instable colorectal cancer. PMID: 25101223 Ref: Presence of FOXP3(+)Treg cells is correlated with colorectal cancer progression. PMID: 25126180 Ref: Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance. PMID: 25225903 Ref: CD4(+) T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory T cells enriched in patients with colorectal cancer. PMID: 25268580 Ref: Association of FoxP3 rs3761548 polymorphism with susceptibility to colorectal cancer in the Chinese population. PMID: 25416053 Ref: Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities. PMID: 25436113 |
Ref: Low infiltration of peritumoral regulatory T cells predicts worse outcome following resection of colorectal liver metastases. PMID: 25120248 Ref: Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases. PMID: 25351619 Ref: FOXP3+ Tregs: heterogeneous phenotypes and conflicting impacts on survival outcomes in patients with colorectal cancer. PMID: 25608795 Ref: Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer. PMID: 25638150 Ref: Increased number of forkhead box P3+ tumor-infiltrating lymphocytes correlates with high preoperative albumin level and better survival in patients with stage II or III colorectal cancer. PMID: 25697896 Ref: Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors. PMID: 25754875 Ref: The prognostic value of FOXP3+ T regulatory cells in colorectal cancer. PMID: 25778305 Ref: Immunoprofiling for prognostic assessment of colon cancer: a novel complement to ultrastaging. PMID: 25808375 Ref: In rectal cancer, the type of desmoplastic response after preoperative chemoradiotherapy is associated with prognosis. PMID: 25820417 Ref: Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients. PMID: 25823653 Ref: Leukocyte mitochondrial DNA content: a novel biomarker associated with prognosis and therapeutic outcome in colorectal cancer. PMID: 25823896 Ref: Tumor Budding Correlates With the Protumor Immune Microenvironment and Is an Independent Prognostic Factor for Recurrence of Stage I Lung Adenocarcinoma. PMID: 25836013 Ref: Systemic Analysis of Predictive Biomarkers for Recurrence in Colorectal Cancer Patients Treated with Curative Surgery. PMID: 25840921 Ref: Recombinant Salmonella-based CEACAM6 and 4-1BBL vaccine enhances T-cell immunity and inhibits the development of colorectal cancer in rats: In vivo effects of vaccine containing 4-1BBL and CEACAM6. PMID: 25872647 Ref: Image analyzer-based assessment of tumor-infiltrating T cell subsets and their prognostic values in colorectal carcinomas. PMID: 25875774 Ref: The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers. PMID: 25906747 Ref: Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial. PMID: 25970543 Ref: Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. PMID: 25984582 Ref: Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice. PMID: 26033215 Ref: Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer. PMID: 26047578 Ref: Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy. PMID: 26060019 Ref: The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis. PMID: 26109431 Ref: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors. PMID: 26155417 Ref: Fusobacterium nucleatum and T Cells in Colorectal Carcinoma. PMID: 26181352 Ref: Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis. PMID: 26201900 Ref: Tumor-infiltrating lymphocytes, forkhead box P3, programmed death ligand-1, and cytotoxic T lymphocyte-associated antigen-4 expressions before and after neoadjuvant chemoradiation in rectal cancer. PMID: 26209749 Ref: Treg-Mediated Immune Tolerance and the Risk of Solid Cancers: Findings From EPIC-Heidelberg. PMID: 26298011 Ref: High intratumoral FOXP3(+) T regulatory cell (Tregs) density is an independent good prognosticator in nodal negative colorectal cancer. PMID: 26339391 Ref: Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy. PMID: 26369701 Ref: OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer. PMID: 26439988 Ref: TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases. PMID: 26483205 Ref: GITR engagement in combination with CTLA-4 blockade completely abrogates immunosuppression mediated by human liver tumor-derived regulatory T cells ex vivo. PMID: 26587321 Ref: IKKbeta acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis. PMID: 26621452 Ref: Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer. PMID: 26645238 |
Ref: Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status. PMID: 25591978 Ref: MicroRNA MIR21 and T Cells in Colorectal Cancer. PMID: 26419959 Ref: A High RORgammaT/CD3 Ratio is a Strong Prognostic Factor for Postoperative Survival in Advanced Colorectal Cancer: Analysis of Helper T Cell Lymphocytes (Th1, Th2, Th17 and Regulatory T Cells). PMID: 26564244 Ref: A Novel Immune Marker Model Predicts Oncological Outcomes of Patients with Colorectal Cancer. PMID: 26581202 Ref: Treatment with cyclophosphamide supported by various dendritic cell-based vaccines induces diversification in CD4(+) T cell response against MC38 colon carcinoma. PMID: 26648160 Ref: Accumulation of FoxP3+ T regulatory cells in the tumor microenvironment of human colorectal adenomas. PMID: 26724144 Ref: Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. PMID: 26811607 Ref: Implication of programmed cell death ligand 1 expression in tumor recurrence and prognosis in rectal cancer with neoadjuvant chemoradiotherapy. PMID: 26919982 Ref: Enrichment of Inflammatory IL-17 and TNF-alpha Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1. PMID: 27014625 Ref: Body mass index and risk of colorectal cancer according to tumor lymphocytic infiltrate. PMID: 27037951 Ref: Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer. PMID: 27057447 Ref: Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers. PMID: 27111280 Ref: Marine omega-3 Polyunsaturated Fatty Acid Intake and Risk of Colorectal Cancer Characterized by Tumor-Infiltrating T Cells. PMID: 27148825 Ref: The number of regulatory Foxp3+ T-cells in different stages of malignant transformation of large intestinal polyps. PMID: 27152766 Ref: Prognostic Utility of Immunoprofiling in Colon Cancer: Results from a Prospective, Multicenter Nodal Ultrastaging Trial. PMID: 27282965 Ref: FOXP3 and CEACAM6 expression and T cell infiltration in the occurrence and development of colon cancer. PMID: 27284373 Ref: Microsatellite instability as a predictive factor for immunotherapy in malignant melanoma. PMID: 27372860 Ref: The Immune Landscapes of Polypoid and Nonpolypoid Precancerous Colorectal Lesions. PMID: 27441558 Ref: Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer. PMID: 27449756 Ref: The Prognostic Significance of FoxP3+ T Cells and CD8+ T Cells in Colorectal Carcinomas. PMID: 27481490 Ref: Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity. PMID: 27494875 Ref: [Phenotypic characteristics of LAP(+) CD4(+) T lymphocytes in colorectal cancer tissues]. PMID: 27531479 Ref: Xenogeneic cell-based vaccine therapy for colorectal cancer: Safety, association of clinical effects with vaccine-induced immune responses. PMID: 27565847 Ref: Determination of a CD4(+)CD25(-)FoxP3(+) T cells subset in tumor-draining lymph nodes of colorectal cancer secreting IL-2 and IFN-gamma. PMID: 27619682 Ref: Inflammatory regulatory T cells in the microenvironments of ulcerative colitis and colon carcinoma. PMID: 27622054 Ref: Arsenic trioxide inhibits lung metastasis of mouse colon cancer via reducing the infiltration of regulatory T cells. PMID: 27677289 Ref: MicroRNA let-7, T Cells, and Patient Survival in Colorectal Cancer. PMID: 27737877 Ref: Foxp3 expression in CD4(+)CD25(+)Foxp3(+) regulatory T cells promotes development of colorectal cancer by inhibiting tumor immunity. PMID: 27752897 Ref: Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer. PMID: 27835889 Ref: Surface Expression of TGFbeta Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer. PMID: 27913437 |
Ref: Tumour CD274 (PD-L1) expression and T cells in colorectal cancer. PMID: 27196573 Ref: Signal Transduction and Activator of Transcription-3 (STAT3) in Patients with Colorectal Cancer: Associations with the Phenotypic Features of the Tumor and Host. PMID: 27678454 Ref: Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity. PMID: 27833053 Ref: The role of lymph node size and FOXP3+ regulatory T cells in node-negative colon cancer. PMID: 27879345 Ref: Tumor-associated immune factors are associated with recurrence and metastasis in non-small cell lung cancer. PMID: 28084319 Ref: Inclusion of BLIMP-1(+) effector regulatory T cells improves the Immunoscore in a cohort of New Zealand colorectal cancer patients: a pilot study. PMID: 28116480 Ref: Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response. PMID: 28177891 Ref: Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer. PMID: 28194445 Ref: Role of LAP(+)CD4(+) T cells in the tumor microenvironment of colorectal cancer. PMID: 28210081 Ref: Tumor-Associated Macrophage Infiltration in Colorectal Cancer Liver Metastases is Associated With Better Outcome. PMID: 28213791 Ref: Tim-3 and its role in regulating anti-tumor immunity. PMID: 28258697 Ref: Tumor-Associated Macrophages and Regulatory T Cells Infiltration and the Clinical Outcome in Colorectal Cancer. PMID: 28343267 Ref: The PD-1 expressing immune phenotype of T cell exhaustion is prominent in the 'immunoreactive' microenvironment of colorectal carcinoma. PMID: 28383777 Ref: Tumor SQSTM1 (p62) expression and T cells in colorectal cancer. PMID: 28405513 Ref: Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer. PMID: 28405523 Ref: Curcumin up regulates T helper 1 cells in patients with colon cancer. PMID: 28469791 Ref: Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells. PMID: 28489607 Ref: KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells. PMID: 28521455 Ref: T cell immunity induced by a bivalent Salmonella-based CEACAM6 and 4-1BBL vaccines in a rat colorectal cancer model. PMID: 28521477 Ref: Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities. PMID: 28535011 Ref: Colorectal tumors are enriched with regulatory plasmablasts with capacity in suppressing T cell inflammation. PMID: 28558303 Ref: Expression of Foxp3 and its prognostic significance in colorectal cancer. PMID: 28560891 Ref: FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells. PMID: 28591725 Ref: Intratumoral FoxP3(+)Helios(+) Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer. PMID: 28603527 Ref: Molecular Signatures of Human Regulatory T Cells in Colorectal Cancer and Polyps. PMID: 28611777 Ref: The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study. PMID: 28677162 Ref: Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenicCD4(+) T-cells and induction of antitumor CD8(+) T-cell activity. PMID: 28680752 Ref: CD103+ Dendritic Cell Function Is Altered in the Colons of Patients with Ulcerative Colitis. PMID: 28700533 Ref: CD19(lo)CD27(hi) Plasmablasts Suppress Harmful Th17 Inflammation Through Interleukin 10 Pathway in Colorectal Cancer. PMID: 28829194 Ref: Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats. PMID: 28848081 Ref: Upregulation of Treg-Related Genes in Addition with IL6 Showed the Significant Role for the Distant Metastasis in Colorectal Cancer. PMID: 28868572 Ref: Neutrophil infiltration is a favorable prognostic factor in early stages of colon cancer. PMID: 28882699 Ref: Regulatory T-cell heterogeneity and the cancer immune response. PMID: 28983402 Ref: Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression. PMID: 29085667 Ref: Tumor-infiltrating FoxP3(+) Tregs predict favorable outcome in colorectal cancer patients: A meta-analysis. PMID: 29088871 Ref: The prognostic value of cancer stem-like cell markers SOX2 and CD133 in stage III colon cancer is modified by expression of the immune-related markers FoxP3, PD-L1 and CD3. PMID: 29102042 Ref: Prediction of radio-responsiveness with immune-profiling in patients with rectal cancer. PMID: 29108360 Ref: The Clinicopathological and Prognostic Implications of FoxP3(+) Regulatory T Cells in Patients with Colorectal Cancer: A Meta-Analysis. PMID: 29209232 Ref: The synergistic antitumor effect of arsenic trioxide combined with cytotoxic T cells in pulmonary metastasis model of colon cancer. PMID: 29312633 |
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