Primary Site >> Liver Cancer
Gene >> FOXO1
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Ref: Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression. PMID: 19563779 Ref: SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis. PMID: 19686743 |
Ref: Muscle atrophy in experimental cancer cachexia: is the IGF-1 signaling pathway involved? PMID: 20039316 |
Ref: FOXO1 stimulates ceruloplasmin promoter activity in human hepatoma cells treated with IL-6. PMID: 21185807 |
Ref: From cirrhosis to hepatocellular carcinoma in HCV-infected patients: genes involved in tumor progression. PMID: 22913147 |
Ref: Inhibition of miR-96 expression reduces cell proliferation and clonogenicity of HepG2 hepatoma cells. PMID: 23151657 Ref: Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells. PMID: 23255113 Ref: FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801. PMID: 24112473 |
Ref: Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus. PMID: 24478438 Ref: Galpha12gep oncogene inhibits FOXO1 in hepatocellular carcinoma as a consequence of miR-135b and miR-194 dysregulation. PMID: 24631529 Ref: MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. PMID: 24690171 Ref: GSK3 protein positively regulates type I insulin-like growth factor receptor through forkhead transcription factors FOXO1/3/4. PMID: 25053419 Ref: Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus-associated hepatocellular carcinoma. PMID: 25141867 Ref: MicroRNA-1269 promotes proliferation in human hepatocellular carcinoma via downregulation of FOXO1. PMID: 25472505 |
Ref: Insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1. PMID: 25627686 Ref: Polymorphisms in microRNA target sites of forkhead box O genes are associated with hepatocellular carcinoma. PMID: 25739100 Ref: Wnt/beta-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. PMID: 25813403 Ref: MicroRNA-3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation. PMID: 25849943 Ref: Adipose tissue-secreted miR-27a promotes liver cancer by targeting FOXO1 in obese individuals. PMID: 25897249 Ref: Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes. PMID: 26201094 Ref: Hepatitis C virus-induced glucose metabolic disorder. PMID: 27760925 |
Ref: Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells. PMID: 26712469 Ref: Protein-protein interactions among signaling pathways may become new therapeutic targets in liver cancer (Review). PMID: 26717966 Ref: Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling. PMID: 26879559 Ref: Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1. PMID: 26893361 Ref: HCV core protein-induced upregulation of microRNA-196a promotes aberrant proliferation in hepatocellular carcinoma by targeting FOXO1. PMID: 27108614 Ref: Aquaporin 9 inhibits hepatocellular carcinoma through up-regulating FOXO1 expression. PMID: 27329843 Ref: miRNA-135a promotes hepatocellular carcinoma cell migration and invasion by targeting forkhead box O1. PMID: 27486383 Ref: Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway. PMID: 27490929 Ref: The oncoprotein HBXIP suppresses gluconeogenesis through modulating PCK1 to enhance the growth of hepatoma cells. PMID: 27609066 Ref: Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-beta pathway. PMID: 27612430 |
Ref: FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition. PMID: 27924058 Ref: MicroRNA-142-5p Overexpression Inhibits Cell Growth and Induces Apoptosis by Regulating FOXO in Hepatocellular Carcinoma Cells. PMID: 28081734 Ref: Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis. PMID: 28302149 Ref: miR-101 suppresses HBV replication and expression by targeting FOXO1 in hepatoma carcinoma cell lines. PMID: 28400278 Ref: Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway. PMID: 28769986 Ref: Downregulation of microRNA-196a inhibits human liver cancer cell proliferation and invasion by targeting FOXO1. PMID: 28791406 Ref: Trifluoperazine Activates FOXO1-Related Signals to Inhibit Tumor Growth in Hepatocellular Carcinoma. PMID: 28876084 Ref: Sex-Differential Responses of Tumor Promotion-Associated Genes and Dysregulation of Novel Long Noncoding RNAs in Constitutive Androstane Receptor-Activated Mouse Liver. PMID: 28903501 Ref: NK3 homeobox 1 (NKX3.1) up-regulates forkhead box O1 expression in hepatocellular carcinoma and thereby suppresses tumor proliferation and invasion. PMID: 28972178 |
Ref: SIRT6 Is a Target of Regulation by UBE3A That Contributes to Liver Tumorigenesis in an ANXA2-Dependent Manner. PMID: 29217762 Ref: Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib. PMID: 29251327 Ref: Metformin Promotes 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Hepatocellular Carcinoma Cells Through FoxO1-Mediated Downregulation of Glucose-6-Phosphatase. PMID: 29256045 Ref: Sestrin2 facilitates glutamine-dependent transcription of PGC-1alpha and survival of liver cancer cells under glucose limitation. PMID: 29436167 Ref: Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines. PMID: 29545174 Ref: Genetic landscape of hepatitis B virus-associated diffuse large B-cell lymphoma. PMID: 29545328 Ref: An autophagy-related gene expression signature for survival prediction in multiple cohorts of hepatocellular carcinoma patients. PMID: 29707114 Ref: Systems analysis of key genes and pathways in the progression of hepatocellular carcinoma. PMID: 29879025 Ref: Overexpression of EPS8L3 promotes cell proliferation by inhibiting the transactivity of FOXO1 in HCC. PMID: 29940761 Ref: Different roles of FAT10, FOXO1, and ADRA2A in hepatocellular carcinoma tumorigenesis in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH). PMID: 30009772 Ref: Self-assembled dual fluorescence nanoparticles for CD44-targeted delivery of anti-miR-27a in liver cancer theranostics. PMID: 30083261 Ref: A circRNA-miRNA-mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma. PMID: 30092792 Ref: Upregulation of microRNA300 induces the proliferation of liver cancer by downregulating transcription factor FOXO1. PMID: 30272296 Ref: Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator. PMID: 30374065 |