Primary Site >> Colorectal Cancer
Gene >> ELAVL1
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Ref: HuR regulates p21 mRNA stabilization by UV light. PMID: 10629032 Ref: HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. PMID: 10811625 |
Ref: Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. PMID: 11733561 |
Ref: RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. PMID: 12821781 Ref: RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation. PMID: 12944397 Ref: Role of the RNA-binding protein HuR in colon carcinogenesis. PMID: 14562043 |
Ref: Global analysis of HuR-regulated gene expression in colon cancer systems of reducing complexity. PMID: 15473260 |
Ref: Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling. PMID: 15946948 Ref: The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells. PMID: 16289864 |
Ref: Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2. PMID: 16799479 Ref: Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR. PMID: 17040897 |
Ref: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts. PMID: 17640979 |
Ref: Increased expression of cytoplasmic HuR in familial adenomatous polyposis. PMID: 18094611 |
Ref: Tissue microarray analysis of 560 patients with colorectal adenocarcinoma: high expression of HuR predicts poor survival. PMID: 19009247 Ref: The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. PMID: 19208339 Ref: Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009. PMID: 19581734 Ref: Cytoplasmic expression of HuR is related to cyclooxygenase-2 expression in colon cancer. PMID: 19707506 |
Ref: Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants. PMID: 20421296 |
Ref: High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells. PMID: 21310943 Ref: Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. PMID: 21317874 Ref: Cancer: Mdm2-regulated stabilization of HuR by neddylation in HCC and colon cancer--a possible target for therapy. PMID: 22158377 |
Ref: The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2. PMID: 22049153 Ref: Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation. PMID: 22095636 Ref: MicroRNA Regulation of SIRT1. PMID: 22479251 Ref: Two in-and-out modulation strategies for endoplasmic reticulum stress-linked gene expression of pro-apoptotic macrophage-inhibitory cytokine 1. PMID: 22511768 Ref: beta-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells. PMID: 22544606 |
Ref: Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis. PMID: 23233214 Ref: Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells. PMID: 23880304 |
Ref: Proteomic analysis reveals that MAEL, a component of nuage, interacts with stress granule proteins in cancer cells. PMID: 24189637 Ref: Pathway and network analysis in glioma with the partial least squares method. PMID: 24815461 Ref: HuR regulates alternative splicing of the TRA2beta gene in human colon cancer cells under oxidative stress. PMID: 24865968 Ref: Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L. PMID: 25010987 Ref: Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development. PMID: 25085247 |
Ref: Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis. PMID: 25663692 Ref: NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R. PMID: 25841271 Ref: Exploiting a novel miR-519c-HuR-ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer. PMID: 26386386 Ref: Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways. PMID: 26442106 |
Ref: Lower muscle density is associated with major postoperative complications in older patients after surgery for colorectal cancer. PMID: 27554247 Ref: Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. PMID: 27677075 Ref: Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1. PMID: 27784781 |
Ref: Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2. PMID: 28219770 Ref: CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype. PMID: 28242812 Ref: HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis. PMID: 28428272 Ref: Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells. PMID: 28968471 |
Ref: The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer. PMID: 29351796 Ref: Up-regulation of miR-324-5p inhibits proliferation and invasion of colorectal cancer cells by targeting ELAVL1. PMID: 29386086 Ref: MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR). PMID: 29471005 Ref: Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer. PMID: 29512763 Ref: Inhibition of IRES-dependent translation of caspase-2 by HuR confers chemotherapeutic drug resistance in colon carcinoma cells. PMID: 29719611 Ref: Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer. PMID: 29931370 Ref: Long noncoding RNA gastric cancer-associated transcript 3 plays oncogenic roles in glioma through sponging miR-3127-5p. PMID: 30317610 Ref: Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes. PMID: 30341421 |