Primary Site >> Colorectal Cancer
Gene >> E2F4
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Ref: Mutations of E2F-4 trinucleotide repeats in colorectal cancer with microsatellite instability. PMID: 8878551 |
Ref: Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. PMID: 9192806 Ref: Drastic genetic instability of tumors and normal tissues in Turcot syndrome. PMID: 9419979 |
Ref: Close correlation between mutations of E2F4 and hMSH3 genes in colorectal cancers with microsatellite instability. PMID: 9485005 Ref: Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences. PMID: 9777938 |
Ref: Causes and consequences of microsatellite instability in endometrial carcinoma. PMID: 9927063 |
Ref: The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. PMID: 10601558 Ref: Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium. PMID: 10717241 Ref: Genomic structure and mutation screening of the E2F4 gene in human tumors. PMID: 10797289 Ref: Multiple tumors and a novel E2F-4 mutation. A case report. PMID: 11025371 |
Ref: Alterations of repeated sequences in 5' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome. PMID: 11526511 Ref: Effect of naturally occurring E2F-4 alterations on transcriptional activation and proliferation in transfected cells. PMID: 11706064 |
Ref: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer. PMID: 11996796 Ref: E2F-4 mutation in hereditary non-polyposis colorectal cancer. PMID: 12148576 Ref: Expression of E2F-4 gene in colorectal adenocarcinoma and corresponding covering mucosa: an immunohistochemistry, image analysis, and immunoblot study. PMID: 12373148 |
Ref: mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma. PMID: 12813132 |
Ref: The nucleocytoplasmic shuttling of E2F4 is involved in the regulation of human intestinal epithelial cell proliferation and differentiation. PMID: 15040009 Ref: Expression of MCM10 and TopBP1 is regulated by cell proliferation and UV irradiation via the E2F transcription factor. PMID: 15195143 |
Ref: Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene. PMID: 17089045 |
Ref: An antisense transcript induced by Wnt/beta-catenin signaling decreases E2F4. PMID: 17121828 Ref: Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells. PMID: 17656449 |
Ref: Mirk regulates the exit of colon cancer cells from quiescence. PMID: 19542220 Ref: E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. PMID: 19562678 Ref: E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. PMID: 19585502 |
Ref: Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT116 Human Colon Cancer Cells; Involvement of Reactive Oxygen Species. PMID: 21311680 |
Ref: 212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint. PMID: 23632482 Ref: E2F transcription factors and digestive system malignancies: how much do we know? PMID: 23745020 Ref: Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4. PMID: 24100580 |
Ref: The relationship between E2F family members and tumor growth in colorectal adenocarcinomas: A comparative immunohistochemical study of 100 cases. PMID: 22688350 |
Ref: A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis. PMID: 28628609 Ref: Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF-beta/Smad pathway in vitro and in vivo. PMID: 29085481 |
Ref: The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling. PMID: 29505855 |