Primary Site >> Colorectal Cancer
Gene >> DYRK1B
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Ref: Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. PMID: 10910078 |
Ref: Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. PMID: 11980910 |
Ref: Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants. PMID: 12455049 |
Ref: Mirk regulates the exit of colon cancer cells from quiescence. PMID: 19542220 Ref: Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells. PMID: 19633423 |
Ref: A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-kappaB pathway. PMID: 23591012 |