Primary Site >> Liver Cancer
Gene >> DNMT3A
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis. PMID: 11230735 |
Ref: Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. PMID: 11844796 |
Ref: Expression of DNA (5-cytosin)-methyltransferases (DNMTs) in hepatocellular carcinomas. PMID: 12850690 |
Ref: DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma. PMID: 15885882 |
Ref: DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation. PMID: 17549390 |
Ref: Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. PMID: 19070387 Ref: Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice. PMID: 19270015 Ref: The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors. PMID: 19482888 |
Ref: Hepatitis B virus X protein induces hypermethylation of p16(INK4A) promoter via DNA methyltransferases in the early stage of HBV-associated hepatocarcinogenesis. PMID: 19732323 Ref: Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter. PMID: 20038433 Ref: Depletion of DNMT3A suppressed cell proliferation and restored PTEN in hepatocellular carcinoma cell. PMID: 20467490 Ref: Epigenetic activation of E-cadherin is a candidate therapeutic target in human hepatocellular carcinoma. PMID: 22993570 |
Ref: microRNA-450a targets DNA methyltransferase 3a in hepatocellular carcinoma. PMID: 22977604 |
Ref: Epigenetic control of metastasis-associated protein 1 gene expression by hepatitis B virus X protein during hepatocarcinogenesis. PMID: 23552838 |
Ref: miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A. PMID: 23124077 Ref: miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells. PMID: 23532995 Ref: DNA methyltransferases 1 and 3B are required for hepatitis C virus infection in cell culture. PMID: 23545144 Ref: Epigenetic silencing of NAD(P)H:quinone oxidoreductase 1 by hepatitis B virus X protein increases mitochondrial injury and cellular susceptibility to oxidative stress in hepatoma cells. PMID: 23920313 Ref: DNMT3A -448A>G polymorphism and the risk for hepatocellular carcinoma. PMID: 24649006 |
Ref: Fumonisin B1 induces global DNA hypomethylation in HepG2 cells - An alternative mechanism of action. PMID: 24280379 Ref: Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway. PMID: 24374650 Ref: [Serum anti-Ku86: a potential biomarker for early detection of hepatocellular carcinoma]. PMID: 24796461 Ref: Modulation of miR-29 expression by alpha-fetoprotein is linked to the hepatocellular carcinoma epigenome. PMID: 24798303 Ref: HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators. PMID: 24941955 Ref: DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model. PMID: 25190601 Ref: Trichloroethylene-induced gene expression and DNA methylation changes in B6C3F1 mouse liver. PMID: 25549359 |
Ref: Hepatitis B virus infection in hepatocellular carcinoma tissues upregulates expression of DNA methyltransferases. PMID: 26064328 Ref: Dendrosomal curcumin increases expression of the long non-coding RNA gene MEG3 via up-regulation of epi-miRs in hepatocellular cancer. PMID: 26321746 |
Ref: Genome-wide profiling of DNA methylation reveals preferred sequences of DNMTs in hepatocellular carcinoma cells. PMID: 26254611 Ref: Hepatitis B virus X protein upregulates DNA methyltransferase 3A/3B and enhances SOCS-1CpG island methylation. PMID: 26573490 Ref: MicroRNA-200b inhibits the proliferation of hepatocellular carcinoma by targeting DNA methyltransferase 3a. PMID: 26986232 Ref: Evaluation of MiR-34 Family and DNA Methyltransferases 1, 3A, 3B Gene Expression Levels in Hepatocellular Carcinoma Following Treatment with Dendrosomal Nanocurcumin. PMID: 27165229 Ref: DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. PMID: 27344963 |
Ref: Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis. PMID: 27939986 Ref: MiR-30b-5p acts as a tumor suppressor, repressing cell proliferation and cell cycle in human hepatocellular carcinoma. PMID: 28273636 Ref: Bidirectional transcription of Linc00441 and RB1 via H3K27 modification-dependent way promotes hepatocellular carcinoma. PMID: 28300839 Ref: HMGA2, a driver of inflammation, is associated with hypermethylation in acute liver injury. PMID: 28502886 |
Ref: Circulating cell-free DNA of methylated insulin-like growth factor-binding protein 7 predicts a poor prognosis in hepatitis B virus-associated hepatocellular carcinoma after hepatectomy. PMID: 29463155 Ref: Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. PMID: 29518473 Ref: Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells. PMID: 29555977 Ref: Lower expression of bone marrow miR-122 is an independent risk factor for overall survival in cytogenetically normal acute myeloid leukemia. PMID: 29627222 Ref: Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. PMID: 29669855 Ref: MiR-876-5p acts as an inhibitor in hepatocellular carcinoma progression by targeting DNMT3A. PMID: 29724530 Ref: Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors. PMID: 29858058 Ref: Effect of Genistein in Comparison with Trichostatin A on Reactivation of DNMTs Genes in Hepatocellular Carcinoma. PMID: 29951358 |