Primary Site >> Stomach Cancer

Gene >> CYP3A4

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Ref: Enhanced expression of cytochrome P450 in stomach cancer.
PMID: 9569036
Ref: Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients.
PMID: 17605821
Ref: Genome-wide gene copy number and expression analysis of primary gastric tumors and gastric cancer cell lines.
PMID: 20187983
Ref: Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer.
PMID: 20878069
Ref: [Effect of jianpi liqi recipe on mRNA expressions of TP, DPD, and CYP3A4 in mice with human gastric cancer transplanted tumor].
PMID: 24325062
Ref: Cross-talk between EPAS-1/HIF-2alpha and PXR signaling pathway regulates multi-drug resistance of stomach cancer cell.
PMID: 26783937
Ref: Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazo l-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).
PMID: 27355974
Ref: Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies.
PMID: 27995989
Ref: Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole.
PMID: 28967981
Ref: Evaluation of the inhibition effects of apatinib on human and rat cytochrome P450.
PMID: 30138636