Primary Site >> Liver Cancer
Gene >> CXCL12
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Ref: Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA). PMID: 7982471 |
Ref: Reduced expression of the CXC chemokine hIRH/SDF-1alpha mRNA in hepatoma and digestive tract cancer. PMID: 9398042 |
Ref: CXCR4 mRNA expression in colon, esophageal and gastric cancers and hepatitis C infected liver. PMID: 10200342 Ref: Reduced expression of the CXCR4 receptor mRNA in hepatocellular carcinoma and lack of inducibility of its ligand alpha-chemokine hIRH/SDF1alpha/PBSF in vitro. PMID: 10200343 |
Ref: Regional expression of CXCL12/CXCR4 in liver and hepatocellular carcinoma and cell-cycle variation during in vitro differentiation. PMID: 12149145 |
Ref: [Which stem cells for adult liver?]. PMID: 15981930 |
Ref: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. PMID: 16380080 Ref: Involvement of c-myc-regulated genes in hepatocellular carcinoma related to genotype-C hepatitis B virus. PMID: 16703398 Ref: Enhanced expression and clinical significance of CC-chemokine MIP-3 alpha in hepatocellular carcinoma. PMID: 16764701 Ref: Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome. PMID: 16794396 Ref: Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. PMID: 16819541 Ref: Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases. PMID: 17075975 |
Ref: Lack of association of some chemokine system polymorphisms with the risks of death and hepatocellular carcinoma occurrence in patients with alcoholic cirrhosis: a prospective study. PMID: 17413295 Ref: Genome wide expression profiling identifies genes associated with colorectal liver metastasis. PMID: 17487416 |
Ref: Chemokine system polymorphisms, survival and hepatocellular carcinoma occurrence in patients with hepatitis C virus-related cirrhosis. PMID: 18205260 |
Ref: Role of the CXCL12/CXCR4 axis in milky spots of rats bearing ascitic-type hepatoma. PMID: 19340530 |
Ref: Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells. PMID: 20380740 Ref: Chemokines and hepatocellular carcinoma. PMID: 20397259 Ref: Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappaB activation in breast and pancreatic tumor cells. PMID: 20699088 |
Ref: CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? PMID: 21349998 |
Ref: CXCR4 expression predicts patient outcome and recurrence patterns after hepatic resection for colorectal liver metastases. PMID: 21584832 Ref: CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer. PMID: 22075627 Ref: Inhibiting effect of Astragalus polysaccharides on the functions of CD4+CD25 highTreg cells in the tumor microenvironment of human hepatocellular carcinoma. PMID: 22490576 |
Ref: Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma. PMID: 23472074 Ref: Overactivation of the TGF-beta pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells. PMID: 23813475 Ref: Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro. PMID: 24141568 |
Ref: Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma. PMID: 24614035 Ref: AEG-1 promotes anoikis resistance and orientation chemotaxis in hepatocellular carcinoma cells. PMID: 24941119 Ref: Insights on the CXCL12-CXCR4 axis in hepatocellular carcinoma carcinogenesis. PMID: 25075251 Ref: Novel synthetic biscoumarins target tumor necrosis factor-alpha in hepatocellular carcinoma in vitro and in vivo. PMID: 25231984 Ref: CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression. PMID: 25341042 |
Ref: CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not. PMID: 25363530 Ref: Novel synthetic coumarins that targets NF-kappaB in Hepatocellular carcinoma. PMID: 25592709 Ref: 4-methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis. PMID: 25882295 Ref: TIMP-1 activated carcinoma-associated fibroblasts inhibit tumor apoptosis by activating SDF1/CXCR4 signaling in hepatocellular carcinoma. PMID: 25909286 |
Ref: Preparation and characterization of a new monoclonal antibody against CXCR4 using lentivirus vector. PMID: 27124560 Ref: Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia. PMID: 27212031 Ref: Stromal cell-derived factor-1 (SDF-1) as a target in liver diseases. PMID: 27313175 Ref: Clinical effects of miR-101 on prognosis of hepatocellular carcinoma and carcinogenic mechanism of anti-miR-101. PMID: 27498785 Ref: Vascular mimicry formation is promoted by paracrine TGF-beta and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma. PMID: 27693460 Ref: Trafficking mechanism of bone marrow-derived mesenchymal stem cells toward hepatocellular carcinoma HepG2 cells by modulating Endoglin, CXCR4 and TGF-beta. PMID: 27755957 Ref: CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients. PMID: 28123896 |
Ref: CXCL12 expression and PD-L1 expression serve as prognostic biomarkers in HCC and are induced by hypoxia. PMID: 27913861 Ref: Hepatitis B virus X protein promotes the stem-like properties of OV6(+) cancer cells in hepatocellular carcinoma. PMID: 28102846 Ref: Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis. PMID: 28302149 Ref: CXCR7/CXCL12 axis is involved in lymph node and liver metastasis of gastric carcinoma. PMID: 28533662 Ref: Microenvironment of a tumor-organoid system enhances hepatocellular carcinoma malignancy-related hallmarks. PMID: 28548903 Ref: Role of C-X-C chemokine ligand 12/C-X-C chemokine receptor 4 in the progression of hepatocellular carcinoma. PMID: 28789425 Ref: Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study. PMID: 29258450 |
Ref: Research progress on the forkhead box C1. PMID: 29552326 Ref: External Beam Radiation Therapy Enhances Mesenchymal Stem Cell-Mediated Sodium-Iodide Symporter Gene Delivery. PMID: 29724129 Ref: CXCL12 and CXCR4 polymorphisms and expressions in peripheral blood from patients of hepatocellular carcinoma. PMID: 29741398 Ref: High co-expression of the SDF1/CXCR4 axis in hepatocarcinoma cells is regulated by AnnexinA7 in vitro and in vivo. PMID: 29783989 Ref: Role of CXCL12 and CXCR4 in the pathogenesis of hematological malignancies. PMID: 29903571 |