Primary Site >> Stomach Cancer
Gene >> CLDN18
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Ref: Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype. PMID: 16435283 Ref: The claudin gene family: expression in normal and neoplastic tissues. PMID: 16836752 Ref: Molecular pathobiology of gastric cancer. PMID: 17249269 |
Ref: Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. PMID: 17459057 |
Ref: Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells. PMID: 18032479 Ref: Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma. PMID: 18251778 Ref: Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection. PMID: 18477216 Ref: Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma. PMID: 18580680 |
Ref: Transcriptome dissection of gastric cancer: identification of novel diagnostic and therapeutic targets from pathology specimens. PMID: 19261089 Ref: Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profiling. PMID: 19398608 |
Ref: Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. PMID: 21381080 Ref: Claudin-18 is an early-stage marker of pancreatic carcinogenesis. PMID: 21832145 Ref: Molecular pathology of gastric cancer: research and practice. PMID: 22005013 |
Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 |
Ref: Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front. PMID: 24073219 |
Ref: Expression of claudin-7 and loss of claudin-18 correlate with poor prognosis in gastric cancer. PMID: 24333468 Ref: miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells. PMID: 24647998 Ref: cDNA-microarray analysis as a new tool to predict lymph node metastasis in gastric cancer. PMID: 24696059 Ref: 4-Amino-2-trifluoromethyl-phenyl retinate inhibits the migration of BGC-823 human gastric cancer cells by downregulating the phosphorylation level of MLC II. PMID: 25051015 |
Ref: New molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee. PMID: 24488015 Ref: Gastric-type expression signature in serrated pathway-associated colorectal tumors. PMID: 25704805 Ref: Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype. PMID: 26033320 Ref: Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity. PMID: 26146084 |
Ref: RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases. PMID: 25823974 Ref: Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer. PMID: 27580354 |
Ref: Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer. PMID: 28494772 |
Ref: DGC-specific RHOA mutations maintained cancer cell survival and promoted cell migration via ROCK inactivation. PMID: 29796182 Ref: A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer. PMID: 29936063 Ref: Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer. PMID: 29961079 Ref: Frequent CLDN18-ARHGAP fusion in highly metastatic diffuse-type gastric cancer with relatively early onset. PMID: 30034621 Ref: Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach. PMID: 30195448 Ref: Claudin18.2-Specific Chimeric Antigen Receptor Engineered T Cells for the Treatment of Gastric Cancer. PMID: 30203099 Ref: A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening. PMID: 30344100 Ref: RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer. PMID: 30361512 |