Primary Site >> Pancreatic Cancer
Gene >> CHRNA4
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Ref: Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines. PMID: 18844224 |
Ref: Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3, alpha5, and alpha7. PMID: 22188668 Ref: Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters. PMID: 22791813 |
Ref: Gamma-amino butyric acid (GABA) prevents the induction of nicotinic receptor-regulated signaling by chronic ethanol in pancreatic cancer cells and normal duct epithelia. PMID: 23213073 |
Ref: Cholinergic receptors as target for cancer therapy in a systems medicine perspective. PMID: 25324001 |
Ref: The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression. PMID: 26264026 |
Ref: Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C. PMID: 27424921 |