Primary Site >> Esophagus Cancer
Gene >> CDKN1A
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Ref: [RB gene expression in gastrointestinal tract]. PMID: 8920658 |
Ref: Involvement of the multiple tumor suppressor genes and 12-lipoxygenase in human prostate cancer. Therapeutic implications. PMID: 9321930 Ref: Correlation between reduced p21(WAF1/CIP1) expression and abnormal p53 expression in esophageal carcinomas. PMID: 21528264 |
Ref: Expression of p53 and p21WAF1/CIP1 proteins in gastric and esophageal cancers: comparison with mutations of the p53 gene. PMID: 9512119 Ref: Alterations in the expression of alpha6beta4 integrin and p21/WAF1/Cip1 in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. PMID: 9537650 Ref: Expression and alteration of p53 and p21(waf1/cip1) influence the sensitivity of chemoradiation therapy for esophageal cancer. PMID: 9840093 |
Ref: Immunohistochemical analysis for cell proliferation-related protein expression in small cell carcinoma of the esophagus; a comparative study with small cell carcinoma of the lung and squamous cell carcinoma of the esophagus. PMID: 10212809 Ref: Expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) and p53 tumor suppressor in dysplastic progression and adenocarcinoma in Barrett esophagus. PMID: 10463972 Ref: p53, p21(Waf1/Cip1) and cyclin D1 protein expression and prognosis in esophageal cancer. PMID: 10466043 Ref: Expression of p21WAF1/Cip1 in the p53-dependent pathway is related to prognosis in patients with advanced esophageal carcinoma. PMID: 10499617 Ref: The prognostic significance of p53, p21 (Waf1/Cip1), and cyclin D1 protein expression in esophageal cancer patients. PMID: 10650815 |
Ref: Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer. PMID: 10656678 Ref: Biological evaluation of undifferentiated carcinoma of the esophagus. PMID: 10791851 Ref: Association between polymorphism in p21(Waf1/Cip1) cyclin-dependent kinase inhibitor gene and human oral cancer. PMID: 10873097 |
Ref: p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues. PMID: 11313979 Ref: Clinical significance and prognostic value of apoptosis related proteins in superficial esophageal squamous cell carcinoma. PMID: 11508622 Ref: [Experimental gene therapy using p21/WAF1 gene in esophageal squamous cell carcinoma--adenovirus infection and gene gun technology]. PMID: 11708000 |
Ref: Growth inhibition of esophageal squamous carcinoma cells by peroxisome proliferator-activated receptor-gamma ligands. PMID: 12080324 Ref: Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1. PMID: 12162406 Ref: Adenovirus-mediated p14ARF gene transfer cooperates with Ad5CMV-p53 to induce apoptosis in human cancer cells. PMID: 12162819 Ref: Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T.Tn expressing non-functional mutated p53. PMID: 12168098 Ref: Esophageal cancer in Chinese population: no polymorphism in codon 149 of P21(Waf1/Cip1) cyclin dependent kinase gene. PMID: 12400017 |
Ref: Enhancement of depsipeptide-mediated apoptosis of lung or esophageal cancer cells by flavopiridol: activation of the mitochondria-dependent death-signaling pathway. PMID: 12771887 Ref: Prediction of lymph node metastasis by p53, p21(Waf1), and PCNA expression in esophageal cancer patients. PMID: 12866574 |
Ref: Expression of p21(Waf1/Cip1) predicts response and survival of esophageal cancer patients treated by chemoradiotherapy. PMID: 15569370 |
Ref: Amplification and functional characterization of MUC1 promoter and gene-virotherapy via a targeting adenoviral vector expressing hSSTR2 gene in MUC1-positive Panc-1 pancreatic cancer cells in vitro. PMID: 15754023 Ref: beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer. PMID: 16114033 Ref: Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells. PMID: 16278420 Ref: KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. PMID: 16357509 |
Ref: Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer. PMID: 16217753 Ref: ECRG1, a novel candidate of tumor suppressor gene in the esophageal carcinoma, triggers a senescent program in NIH3T3 cells. PMID: 16380648 Ref: Id-1 promotes proliferation of p53-deficient esophageal cancer cells. PMID: 16506209 Ref: Relationship between HPV16/18 E6 and 53, 21WAF1, MDM2, Ki67 and cyclin D1 expression in esophageal squamous cell carcinoma: comparative study by using tissue microarray technology. PMID: 17080019 |
Ref: Involvement of IFN regulatory factor (IRF)-1 and IRF-2 in the formation and progression of human esophageal cancers. PMID: 17363571 |
Ref: T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation. PMID: 17532042 Ref: Effects of Oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism. PMID: 18563331 |
Ref: RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses. PMID: 19407849 |
Ref: p21 Waf1/Cip1 polymorphisms and risk of esophageal cancer. PMID: 20112071 |
Ref: Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma. PMID: 21084391 |
Ref: p53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation. PMID: 22990386 Ref: MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo. PMID: 22994740 |
Ref: Correlation analysis of c-myc, p21(WAF/CIP1), p53, C-erbB-2 and COX-2 proteins in esophageal squamous cell carcinoma. PMID: 23177619 Ref: Jaridonin, a novel ent-kaurene diterpenoid from Isodon rubescens, inducing apoptosis via production of reactive oxygen species in esophageal cancer cells. PMID: 23597192 Ref: Upregulation of Ying Yang 1 (YY1) suppresses esophageal squamous cell carcinoma development through heme oxygenase-1. PMID: 23919806 |
Ref: Small molecule agonists of PPAR-gamma exert therapeutic effects in esophageal cancer. PMID: 24272485 Ref: Association between SNPs in P53 binding regions and risk of esophageal squamous cell carcinoma. PMID: 24474449 Ref: Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells. PMID: 24788582 Ref: The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma. PMID: 24980814 |
Ref: Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells. PMID: 25733817 Ref: HOI-02 induces apoptosis and G2-M arrest in esophageal cancer mediated by ROS. PMID: 26469961 |
Ref: Miz-1 promotes the proliferation of esophageal cancer cells via suppression of p21 and release of p21-arrested cyclin D1. PMID: 27109891 Ref: RhBMP-2 Activates Hippo Signaling through RASSF1 in Esophageal Cancer Cells. PMID: 27230238 Ref: Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma. PMID: 27295551 Ref: Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species. PMID: 27863415 Ref: Hesa-A Effects on Cell Cycle Signaling in Esophageal Carcinoma Cell Line. PMID: 27957293 |
Ref: Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors. PMID: 28258440 Ref: miRNA-200c enhances radiosensitivity of esophageal cancer by cell cycle arrest and targeting P21. PMID: 28402920 Ref: ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro. PMID: 28713162 |
Ref: Upregulated long non-coding RNA SBF2-AS1 promotes proliferation in esophageal squamous cell carcinoma. PMID: 29552140 |