Primary Site >> Pancreatic Cancer
Gene >> BRD4
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Ref: BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen. PMID: 24807963 |
Ref: GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1. PMID: 25807524 |
Ref: Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells. PMID: 27769070 |
Ref: BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo. PMID: 28194432 Ref: Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner. PMID: 28369619 Ref: Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. PMID: 28986391 |