Primary Site >> Colorectal Cancer
Gene >> BMI1
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|
|
Ref: Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells. PMID: 19568234 Ref: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. PMID: 19935649 |
Ref: Polycomb group protein Bmi1 expression in colon cancers predicts the survival. PMID: 19957112 |
Ref: MicroRNA expression profile of colon cancer stem-like cells in HT29 adenocarcinoma cell line. PMID: 21130073 Ref: Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells. PMID: 21368208 Ref: [Mechanism of polycomb Bmi1-targeted therapy for colorectal cancer]. PMID: 21866458 |
Ref: TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer. PMID: 22130667 Ref: Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer. PMID: 22170051 Ref: Oncogenicity of the developmental transcription factor Sox9. PMID: 22246670 Ref: Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells. PMID: 22384170 Ref: IL-1beta promotes stemness and invasiveness of colon cancer cells through Zeb1 activation. PMID: 23174018 |
Ref: In situ validation of an intestinal stem cell signature in colorectal cancer. PMID: 22637696 Ref: MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene. PMID: 23255074 Ref: Intestinal stem cells - types and markers. PMID: 23471862 Ref: Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer. PMID: 24312366 |
Ref: Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer. PMID: 23955081 Ref: Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway. PMID: 24911876 Ref: Plasma Bmi1 mRNA as a potential prognostic biomarker for distant metastasis in colorectal cancer patients. PMID: 25054051 Ref: Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer. PMID: 25187386 Ref: Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer. PMID: 25243792 |
Ref: Involvement of heat shock protein a4/apg-2 in refractory inflammatory bowel disease. PMID: 25437815 Ref: Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p. PMID: 25569100 Ref: Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. PMID: 25653233 Ref: Clinical implications of intestinal stem cell markers in colorectal cancer. PMID: 25657049 Ref: The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation. PMID: 25775580 Ref: Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine. PMID: 26046762 Ref: Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels. PMID: 26109429 Ref: Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells. PMID: 26185996 Ref: Regulation of miRNAs by agents targeting the tumor stem cell markers DCLK1, MSI1, LGR5, and BMI1. PMID: 26366338 |
Ref: Cancer stem cells in human digestive tract malignancies. PMID: 26446457 Ref: IL-32theta inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer. PMID: 26824417 Ref: Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer. PMID: 26930714 Ref: Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer. PMID: 27029058 Ref: The prognostic value of polycomb group protein B-cell-specific moloney murine leukemia virus insertion site 1 in stage II colon cancer patients. PMID: 27102362 Ref: Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. PMID: 27225481 Ref: Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer. PMID: 27260988 Ref: Significance of BMI1 and FSCN1 expression in colorectal cancer. PMID: 27488323 Ref: BMI1 is downregulated by the natural compound curcumin, but not by bisdemethoxycurcumin and dimethoxycurcumin. PMID: 27550987 Ref: Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development. PMID: 27846243 |
Ref: Prognostic significance of stromal GREM1 expression in colorectal cancer. PMID: 28041973 Ref: Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells. PMID: 28148261 Ref: Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion. PMID: 28176811 Ref: Fas signaling induces stemness properties in colorectal cancer by regulation of Bmi1. PMID: 28543447 Ref: NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer. PMID: 28598238 Ref: Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata. PMID: 28598616 Ref: Deregulated expression of microRNA-200b/c and SUZ12, a Polycomb repressive complex 2 subunit, in chemoresistant colorectal cancer cells. PMID: 28966728 |
Ref: Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis. PMID: 29203393 Ref: A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer. PMID: 29329541 Ref: BMI1 activates WNT signaling in colon cancer by negatively regulating the WNT antagonist IDAX. PMID: 29337063 Ref: miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer. PMID: 29374066 Ref: Modified miR-15a has therapeutic potential for improving treatment of advanced stage colorectal cancer through inhibition of BCL2, BMI1, YAP1 and DCLK1. PMID: 29416778 Ref: Deptor Is a Novel Target of Wnt/beta-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth. PMID: 29666061 Ref: The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells. PMID: 29772566 Ref: R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells. PMID: 29886802 Ref: Anticancer effects of miR-200c in colorectal cancer through BMI1. PMID: 30171714 |