Primary Site >> Colorectal Cancer
Gene >> BAD
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Ref: 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. PMID: 9792140 |
Ref: Surgery may be curative for patients with a localized perforation of rectal carcinoma. PMID: 10583294 |
Ref: The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage. PMID: 12482325 Ref: Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells. PMID: 12566304 Ref: Antisense protein kinase A RIalpha acts synergistically with hydroxycamptothecin to inhibit growth and induce apoptosis in human cancer cells: molecular basis for combinatorial therapy. PMID: 12631623 Ref: 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-alpha-mediated apoptosis. PMID: 12842827 |
Ref: Inactivating mutations of proapoptotic Bad gene in human colon cancers. PMID: 15033904 |
Ref: Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. PMID: 15695406 |
Ref: Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis. PMID: 16649252 Ref: Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells. PMID: 17016662 |
Ref: Colorectal cancer treatment in elderly patients: results of a retrospective analysis addressed to the chiefs of medical oncology units in Italy. PMID: 17972523 |
Ref: Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells. PMID: 19144873 Ref: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer. PMID: 19609961 Ref: trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis. PMID: 19857056 Ref: The anticancer effects of sodium selenite and selenomethionine on human colorectal carcinoma cell lines in nude mice. PMID: 19911698 |
Ref: Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability. PMID: 19921695 |
Ref: ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. PMID: 21347233 Ref: [Study of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic and inflammatory gene expressions in colon cancer cell line]. PMID: 22030783 |
Ref: Resistance of colon cancer to 5-fluorouracil may be overcome by combination with chloroquine, an in vivo study. PMID: 22561420 Ref: Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis. PMID: 22564437 |
Ref: T-18, a stemonamide synthetic intermediate inhibits Pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug. PMID: 23314349 Ref: Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole andrographolide derivatives. PMID: 23472133 Ref: Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis: early target in the anticancer strategy. PMID: 23514809 Ref: Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation. PMID: 23872169 Ref: Soy soluble polysaccharide induces apoptosis in HCT116 human colon cancer cells via reactive oxygen species generation. PMID: 24126443 Ref: N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo. PMID: 24127835 Ref: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway. PMID: 24241351 |
Ref: Anticancer effect of a curcumin derivative B63: ROS production and mitochondrial dysfunction. PMID: 24274397 Ref: Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells. PMID: 24602180 Ref: S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-beta signaling pathway in cancer cells. PMID: 24970681 Ref: Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells. PMID: 25370813 |
Ref: GRP78 mediates the therapeutic efficacy of curcumin on colon cancer. PMID: 25277658 Ref: BAD-mediated apoptotic pathway is associated with human cancer development. PMID: 25653146 Ref: Synthesis and biological evaluation of a novel betulinic acid derivative as an inducer of apoptosis in human colon carcinoma cells (HT-29). PMID: 26248310 Ref: Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer. PMID: 26328044 Ref: Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status. PMID: 26606169 Ref: Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways. PMID: 26770191 |
Ref: The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells. PMID: 26846577 Ref: Luffa echinata Roxb. Induced Apoptosis in Human Colon Cancer Cell (SW-480) in the Caspase-dependent Manner and Through a Mitochondrial Apoptosis Pathway. PMID: 27019558 Ref: Depletion of UBA protein 2-like protein inhibits growth and induces apoptosis of human colorectal carcinoma cells. PMID: 27456362 Ref: Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action. PMID: 27716288 Ref: [Clostridium septicum aortitis : case report and update on infectious aortitis]. PMID: 28686395 |
Ref: Breaking bad news to patients with cancer: A randomized control trial of a brief communication skills training module incorporating the stories and preferences of actual patients. PMID: 27876220 Ref: Acai Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice. PMID: 27965474 Ref: Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines. PMID: 28477945 Ref: ICT1 predicts a poor survival and correlated with cell proliferation in diffuse large B-cell lymphoma. PMID: 28629825 Ref: M4IDP, a zoledronic acid derivative, induces G1 arrest, apoptosis and autophagy in HCT116 colon carcinoma cells via blocking PI3K/Akt/mTOR pathway. PMID: 28751160 Ref: Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells. PMID: 28981607 |
Ref: shRNA-induced silencing of Ras-related C3 botulinum toxin substrate 1 inhibits the proliferation of colon cancer cells through upregulation of BAD and downregulation of cyclin D1. PMID: 29286138 Ref: Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain? PMID: 29307628 Ref: Drug-like dietary vanilloids induce anticancer activity through proliferation inhibition and regulation of bcl-related apoptotic proteins. PMID: 29464796 Ref: Spatial mutation patterns as markers of early colorectal tumor cell mobility. PMID: 29760052 Ref: shRNAinduced knockdown of the SPERT gene inhibits proliferation and promotes apoptosis of human colorectal cancer RKO cells. PMID: 29845259 Ref: Bufalin and 5-fluorouracil synergistically induce apoptosis in colorectal cancer cells. PMID: 29849804 Ref: Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells. PMID: 29860266 Ref: Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation. PMID: 30056019 Ref: Evaluation of potential anti-cancer activity of cationic liposomal nanoformulated Lycopodium clavatum in colon cancer cells. PMID: 30104445 Ref: [Expression of stem cell markers CD44 and Lgr5 in colorectal cancer and its relationship with lymph node and liver metastasis]. PMID: 30293346 |