Primary Site >> Colorectal Cancer
Gene >> ATOH1
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Ref: Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells. PMID: 15342386 |
Ref: A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma. PMID: 16382053 |
Ref: HATH1 expression in mucinous cancers of the colorectum and related lesions. PMID: 17000673 |
Ref: Reciprocal targeting of Hath1 and beta-catenin by Wnt glycogen synthase kinase 3beta in human colon cancer. PMID: 17241872 |
Ref: Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer. PMID: 18275842 |
Ref: Atonal homolog 1 is a tumor suppressor gene. PMID: 19243219 Ref: The wnt target jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells. PMID: 19622776 |
Ref: NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. PMID: 20145124 Ref: [Hath1 gene transfer inhibits the proliferation of colonic cancer cells in vitro]. PMID: 20501407 Ref: Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells. PMID: 20621629 |
Ref: Complex interplay between beta-catenin signalling and Notch effectors in intestinal tumorigenesis. PMID: 21205878 Ref: Gamma-secretase inhibitor, a potential target therapy for MUC2-positive colorectal carcinoma. PMID: 21520992 Ref: NOTCH Signaling and ATOH1 in Colorectal Cancers. PMID: 21980310 |
Ref: Hath1 inhibits proliferation of colon cancer cells probably through up-regulating expression of Muc2 and p27 and down-regulating expression of cyclin D1. PMID: 23464457 |
Ref: Notch in the intestine: regulation of homeostasis and pathogenesis. PMID: 23190077 Ref: The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein. PMID: 23333391 Ref: SPDEF functions as a colorectal tumor suppressor by inhibiting beta-catenin activity. PMID: 23376423 Ref: Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study. PMID: 23409082 Ref: Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo. PMID: 23418447 |
Ref: Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling. PMID: 25263446 Ref: Atonal homolog 1 protein stabilized by tumor necrosis factor alpha induces high malignant potential in colon cancer cell line. PMID: 26017781 |
Ref: MUC4 is negatively regulated through the Wnt/beta-catenin pathway via the Notch effector Hath1 in colorectal cancer. PMID: 27551331 Ref: Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKClambda/iota. PMID: 27653691 |
Ref: Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. PMID: 28045589 Ref: Delta-like 4/Notch signaling promotes Apc (Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms. PMID: 28086833 Ref: Metformin depresses overactivated Notch1/Hes1 signaling in colorectal cancer patients with type 2 diabetes mellitus. PMID: 28177944 |
Ref: Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals. PMID: 29436668 Ref: SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma. PMID: 29786668 Ref: MicroRNA-613 promotes colon cancer cell proliferation, invasion and migration by targeting ATOH1. PMID: 30219232 |