Primary Site >> Esophagus Cancer

miRNA >> miR-21

Database Links
miRBase_DE: Homo sapiens miR-21 stem-loop
miRBase: hsa-mir-21
EntrezGene: MIR21
HGNC: MIR21
Literature
Journal: Oncogene.2008 Jul 17;27(31):4373-9
Title: MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.
Author: Lu, Z|Liu, M|Stribinskis, V|Klinge, C M|Ramos, K S|Colburn, N H|Li, Y
PMID: 18372920
Journal: Clinical cancer research : an official journal of the American Association for.2009 Mar 15;15(6):1915-22
Title: MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma.
Author: Hiyoshi, Yukiharu|Kamohara, Hidenobu|Karashima, Ryuichi|Sato, Nobutaka|Imamura, Yu|Nagai, Youhei|Yoshida, Naoya|Toyama, Eiichiro|Hayashi, Naoko|Watanabe, Masayuki|Baba, Hideo
PMID: 19276261
Journal: Clinical cancer research : an official journal of the American Association for.2009 Oct 01;15(19):6192-200
Title: MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival.
Author: Mathe, Ewy A|Nguyen, Giang Huong|Bowman, Elise D|Zhao, Yiqiang|Budhu, Anuradha|Schetter, Aaron J|Braun, Rosemary|Reimers, Mark|Kumamoto, Kensuke|Hughes, Duncan|Altorki, Nasser K|Casson, Alan G|Liu, Chang-Gong|Wang, Xin Wei|Yanaihara, Nozomu|Hagiwara, Nobutoshi|Dannenberg, Andrew J|Miyashita, Masao|Croce, Carlo M|Harris, Curtis C
PMID: 19789312
Journal: International journal of cancer.2011 Jan 01;128(1):132-43
Title: Prognostic significance of differentially expressed miRNAs in esophageal cancer.
Author: Hu, Yuxin|Correa, Arlene M|Hoque, Ashraful|Guan, Baoxiang|Ye, Fei|Huang, Jie|Swisher, Stephen G|Wu, Tsung Teh|Ajani, Jaffer A|Xu, Xiao-Chun
PMID: 20309880
Journal: Molecular biology reports.2011 Jun;38(5):3253-60
Title: Role of microRNA-21 and effect on PTEN in Kazakh's esophageal squamous cell carcinoma.
Author: Ma, Wen-Jing|Lv, Guo-Dong|Tuersun, Aerziguli|Liu, Qing|Liu, Hui|Zheng, Shu-Tao|Huang, Cong-Gai|Feng, Jun-Guo|Wang, Xing|Lin, Ren-Yong|Sheyhidin, Ilyar|Lu, Xiao-Mei
PMID: 21104017
Journal: Diseases of the esophagus : official journal of the International Society for.2011 Sep;24(7):523-30
Title: Relationship between altered expression levels of MIR21, MIR143, MIR145, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma.
Author: Akagi, I|Miyashita, M|Ishibashi, O|Mishima, T|Kikuchi, K|Makino, H|Nomura, T|Hagiwara, N|Uchida, E|Takizawa, T
PMID: 21453382
Journal: Diseases of the esophagus : official journal of the International Society for.2012 Apr;25(3):263-8
Title: Programmed cell death 4 nuclear loss and miR-21 or activated Akt overexpression in esophageal squamous cell carcinogenesis.
Author: Fassan, M|Realdon, S|Pizzi, M|Balistreri, M|Battaglia, G|Zaninotto, G|Ancona, E|Rugge, M
PMID: 21883657
Journal: PloS one.2012;7(2):e30590
Title: Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling.
Author: Subramaniam, Dharmalingam|Ponnurangam, Sivapriya|Ramamoorthy, Prabhu|Standing, David|Battafarano, Richard J|Anant, Shrikant|Sharma, Prateek
PMID: 22363450
Journal: Carcinogenesis.2012 Sep;33(9):1736-44
Title: Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer.
Author: Alder, Hansjuerg|Taccioli, Cristian|Chen, Hongping|Jiang, Yubao|Smalley, Karl J|Fadda, Paolo|Ozer, Hatice G|Huebner, Kay|Farber, John L|Croce, Carlo M|Fong, Louise Y Y
PMID: 22689922
Journal: Diseases of the esophagus : official journal of the International Society for.2013 Nov-Dec;26(8):823-31
Title: Inhibition of microRNA-21 increases radiosensitivity of esophageal cancer cells through phosphatase and tensin homolog deleted on chromosome 10 activation.
Author: Huang, S|Li, X-Q|Chen, Xin|Che, S-M|Chen, W|Zhang, X-Z
PMID: 22958183
Journal: Oncology reports.2013 Jan;29(1):169-76
Title: Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma.
Author: Yang, Miao|Liu, Ran|Sheng, Jingyi|Liao, Juan|Wang, Yi|Pan, Enchun|Guo, Wei|Pu, Yuepu|Yin, Lihong
PMID: 23124769
Journal: International journal of cancer.2013 Jun 15;132(12):2901-9
Title: microRNA and inflammatory gene expression as prognostic marker for overall survival in esophageal squamous cell carcinoma.
Author: Zhao, Yiqiang|Schetter, Aaron J|Yang, Geoffrey B|Nguyen, Giang|Mathe, Ewy A|Li, Peng|Cai, Hong|Yu, Lei|Liu, Fangfang|Hang, Dong|Yang, Haijun|Wang, Xin Wei|Ke, Yang|Harris, Curtis C
PMID: 23175214
Journal: Cancer.2013 Jun 01;119(11):1985-93
Title: Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma.
Author: Chen, Zheng|Saad, Rama|Jia, Peilin|Peng, DunFa|Zhu, Shoumin|Washington, M Kay|Zhao, Zhongming|Xu, Zekuan|El-Rifai, Wael
PMID: 23456798
Journal: Asian Pacific journal of cancer prevention : APJCP.2012;13(12):6145-9
Title: Saliva supernatant miR-21: a novel potential biomarker for esophageal cancer detection.
Author: Xie, Zi-Jun|Chen, Gang|Zhang, Xu-Chao|Li, Dong-Feng|Huang, Jian|Li, Zi-Jun
PMID: 23464420
Journal: Digestive diseases and sciences.2013 Jul;58(7):1863-70
Title: MiR-21 down-regulation suppresses cell growth, invasion and induces cell apoptosis by targeting FASL, TIMP3, and RECK genes in esophageal carcinoma.
Author: Wang, Na|Zhang, Chao-Qi|He, Jia-Huan|Duan, Xiao-Fei|Wang, Yuan-Yuan|Ji, Xiang|Zang, Wen-Qiao|Li, Min|Ma, Yun-Yun|Wang, Tao|Zhao, Guo-Qiang
PMID: 23504349
Journal: PloS one.2013;8(4):e57502
Title: Salivary microRNAs as promising biomarkers for detection of esophageal cancer.
Author: Xie, Zijun|Chen, Gang|Zhang, Xuchao|Li, Dongfeng|Huang, Jian|Yang, Cuiqin|Zhang, Pingyong|Qin, Yuxuan|Duan, Yifan|Gong, Bo|Li, Zijun
PMID: 23560033
Journal: PloS one.2013;8(5):e64463
Title: Deciphering the unique microRNA signature in human esophageal adenocarcinoma.
Author: Saad, Rama|Chen, Zheng|Zhu, Shoumin|Jia, Peilin|Zhao, Zhongming|Washington, M Kay|Belkhiri, Abbes|El-Rifai, Wael
PMID: 23724052
Journal: Cancer letters.2014 Jan 01;342(1):121-9
Title: MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer.
Author: Zhang, Fang|Yang, Zhiping|Cao, Minjun|Xu, Yinsheng|Li, Jintao|Chen, Xuebin|Gao, Zhi|Xin, Jing|Zhou, Shaomei|Zhou, Zhixiang|Yang, Yishu|Sheng, Wang|Zeng, Yi
PMID: 24001611
Journal: Seminars in cancer biology.2013 Dec;23(6 Pt B):512-21
Title: A review of the current understanding and clinical utility of miRNAs in esophageal cancer.
Author: Sakai, Naomi S|Samia-Aly, Emma|Barbera, Mariagnese|Fitzgerald, Rebecca C
PMID: 24013023
Journal: PloS one.2013;8(9):e73009
Title: Expression, tissue distribution and function of miR-21 in esophageal squamous cell carcinoma.
Author: Nouraee, Nazila|Van Roosbroeck, Katrien|Vasei, Mohammad|Semnani, Shahriar|Samaei, Nader Mansour|Naghshvar, Farshad|Omidi, Abbas Ali|Calin, George A|Mowla, Seyed Javad
PMID: 24039846
Journal: Digestive diseases and sciences.2013 Dec;58(12):3483-93
Title: Down-regulation of PTEN expression modulated by dysregulated miR-21 contributes to the progression of esophageal cancer.
Author: Li, Pei|Mao, Wei-Min|Zheng, Zhi-Guo|Dong, Zi-Ming|Ling, Zhi-Qiang
PMID: 24221338
Journal: Anticancer research.2013 Dec;33(12):5407-14
Title: A novel chemotherapeutic arene ruthenium(II) drug Rawq01 altered the effect of microRNA-21 on PTEN/AKT signaling pathway in esophageal cancer cells.
Author: Weng, Wenhao|Wu, Qiong|Yu, Yongchun|Mei, Wenjie|Wang, Xinghe
PMID: 24324076
Journal: Biochemical and biophysical research communications.2014 Apr 18;446(4):1197-203
Title: The expression of miR-21 and miR-375 predict prognosis of esophageal cancer.
Author: Fu, Chengrui|Dong, Wei|Wang, Zhiwu|Li, Hongsheng|Qin, Qin|Li, Baosheng
PMID: 24680681
Journal: TheScientificWorldJournal.2014;2014:523979
Title: The microRNAs as prognostic biomarkers for survival in esophageal cancer: a meta-analysis.
Author: Fu, Wenbo|Pang, Lijuan|Chen, Yunzhao|Yang, Lan|Zhu, Janbo|Wei, Yutao
PMID: 25097879
Journal: Disease markers.2014;2014:232837
Title: MicroRNA-21 promotes cell growth and migration by targeting programmed cell death 4 gene in Kazakh's esophageal squamous cell carcinoma.
Author: Liu, Tao|Liu, Qing|Zheng, Shutao|Gao, Xiangpeng|Lu, Mang|Yang, Chenchen|Dai, Fang|Sheyhidin, Ilyar|Lu, Xiaomei
PMID: 25400316
Journal: Genetics and molecular research : GMR.2015 Jun 12;14(2):6578-82
Title: Association of miR-21 with esophageal cancer prognosis: a meta-analysis.
Author: Wen, S-W|Zhang, Y-F|Li, Y|Liu, Z-X|Lv, H-L|Li, Z-H|Xu, Y-Z|Zhu, Y-G|Tian, Z-Q
PMID: 26125864
Journal: Genetics and molecular research : GMR.2015 Aug 03;14(3):8810-8
Title: Characterization and effects of miR-21 expression in esophageal cancer.
Author: Wen, S-W|Zhang, Y-F|Li, Y|Liu, Z-X|Lv, H-L|Li, Z-H|Xu, Y-Z|Zhu, Y-G|Tian, Z-Q
PMID: 26345812
Journal: Acta oncologica (Stockholm, Sweden).2015;54(9):1582-91
Title: Evaluation of miR-21 and miR-375 as prognostic biomarkers in esophageal cancer.
Author: Winther, Mette|Alsner, Jan|Tramm, Trine|Baeksgaard, Lene|Holtved, Eva|Nordsmark, Marianne
PMID: 26481465
Journal: Oncotarget.2016 Mar 08;7(10):10723-38
Title: MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency.
Author: Fong, Louise Y|Taccioli, Cristian|Jing, Ruiyan|Smalley, Karl J|Alder, Hansjuerg|Jiang, Yubao|Fadda, Paolo|Farber, John L|Croce, Carlo M
PMID: 26918602
Journal: International journal of oncology.2016 Jun;48(6):2567-79
Title: Exosome-shuttling microRNA-21 promotes cell migration and invasion-targeting PDCD4 in esophageal cancer.
Author: Liao, Juan|Liu, Ran|Shi, Ya-Juan|Yin, Li-Hong|Pu, Yue-Pu
PMID: 27035745
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental.2016 Sep;37(9):12061-12070
Title: MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer.
Author: Wu, Yan-Ran|Qi, Hai-Jun|Deng, Dan-Fang|Luo, Ying-Ying|Yang, Sheng-Lan
PMID: 27188433
Journal: Pathology, research and practice.2017 Feb;213(2):83-88
Title: Epigenetic regulation on the gene expression signature in esophagus adenocarcinoma.
Author: Xi, Ting|Zhang, Guizhi
PMID: 28049580
Journal: Cancer biomarkers : section A of Disease markers.2017;19(1):1-9
Title: MicroRNAs in esophageal squamous cell carcinoma: Potential biomarkers and therapeutic targets.
Author: Mei, Li-Li|Qiu, Yun-Tan|Zhang, Bing|Shi, Zhi-Zhou
PMID: 28269750
Journal: Oncotarget.2017 May 30;8(22):35681-35699
Title: Identification of molecular targets for esophageal carcinoma diagnosis using miRNA-seq and RNA-seq data from The Cancer Genome Atlas: a study of 187 cases.
Author: Zeng, Jiang-Hui|Xiong, Dan-Dan|Pang, Yu-Yan|Zhang, Yu|Tang, Rui-Xue|Luo, Dian-Zhong|Chen, Gang
PMID: 28415685
Journal: Oncology reports.2017 Aug;38(2):1181-1189
Title: MicroRNA and target mRNA selection through invasion and cytotoxicity cell modeling and bioinformatics approaches in esophageal squamous cell carcinoma.
Author: Lu, Mu|Song, Yaqin|Fu, Wenbo|Liu, Yang|Huai, Shitao|Cui, Xiaobin|Pang, Lijuan|Yang, Lan|Wei, Yutao
PMID: 28677800