Colon Cancer: Gene >> POLK

Mutation ID	1
Mutation Consequence	missense_variant;splice_region_variant
Transcription ID	ENST00000241436
Start	75584926:75584926(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1226G>T
AA Mutation	p.Arg409Met(p.R409M)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75597751:75597751(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2490C>A
AA Mutation	p.Ser830Arg(p.S830R)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75596980:75596980(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2287T>A
AA Mutation	p.Tyr763Asn(p.Y763N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75598012:75598012(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2607T>A
AA Mutation	p.Phe869Leu(p.F869L)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75587048:75587048(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1249A>T
AA Mutation	p.Ser417Cys(p.S417C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75569371:75569371(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.287G>T
AA Mutation	p.Ser96Ile(p.S96I)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75596535:75596535(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1842G>T
AA Mutation	p.Glu614Asp(p.E614D)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75581406:75581406(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs200548318
CDS Mutation	c.892C>T
AA Mutation	p.Arg298Cys(p.R298C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	missense_variant
Transcription ID	ENST00000241436
Start	75596276:75596276(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1583G>T
AA Mutation	p.Ser528Ile(p.S528I)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000241436
Start	75596805:75596805(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2112A>G
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000241436
Start	75576878:75576878(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.639T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000241436
Start	75596401:75596401(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.1713delA
AA Mutation	p.Lys571AsnfsTer18(p.K571Nfs*18)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000241436
Start	75598007:75598007(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.2607delT
AA Mutation	p.Phe869LeufsTer5(p.F869Lfs*5)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	stop_gained
Transcription ID	ENST00000241436
Start	75547110:75547110(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.88G>T
AA Mutation	p.Gly30Ter(p.G30*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Rectum Cancer: Gene >> POLK

Mutation ID	1
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000241436
Start	75596538:75596538(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1845T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000241436
Start	75596229:75596229(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1536G>A
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	stop_gained;frameshift_variant
Transcription ID	ENST00000241436
Start	75597137:75597138(version: GRCh38)
Mutation Type	INS
dbSNP_RS	novel
CDS Mutation	c.2444_2445insATATTCATTTTTTTTCTTTTGAGTTTCATTTGTGGGTCATTTC
AA Mutation	p.Phe815LeufsTer8(p.F815Lfs*8)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	stop_lost
Transcription ID	ENST00000241436
Start	75598016:75598016(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2611T>G
AA Mutation	p.Ter871GluextTer11(p.*871Eext*11)
Mutation Classification	Nonstop_Mutation
Feature Type	Transcript