Colon Cancer: Gene >> MELK

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36657293:36657293(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs370552987
CDS Mutation	c.1106C>T
AA Mutation	p.Ala369Val(p.A369V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36671002:36671002(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs200746617
CDS Mutation	c.1510C>T
AA Mutation	p.Arg504Cys(p.R504C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36589582:36589582(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs769278274
CDS Mutation	c.191T>C
AA Mutation	p.Leu64Pro(p.L64P)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36589627:36589627(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.236C>A
AA Mutation	p.Ala79Asp(p.A79D)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36643021:36643021(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs374744271
CDS Mutation	c.859G>A
AA Mutation	p.Val287Ile(p.V287I)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36677177:36677177(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1796A>G
AA Mutation	p.Gln599Arg(p.Q599R)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36671145:36671145(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1653A>T
AA Mutation	p.Arg551Ser(p.R551S)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36677298:36677298(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1917A>C
AA Mutation	p.Lys639Asn(p.K639N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36677279:36677279(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1898G>A
AA Mutation	p.Gly633Asp(p.G633D)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36677324:36677324(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1943G>C
AA Mutation	p.Ser648Thr(p.S648T)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000298048
Start	36657330:36657330(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs762432984
CDS Mutation	c.1143A>G
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000298048
Start	36607599:36607599(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs571831491
CDS Mutation	c.592C>T
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000298048
Start	36665505:36665506(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.1333_1334delAA
AA Mutation	p.Lys445AspfsTer4(p.K445Dfs*4)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000298048
Start	36581733:36581733(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	null
CDS Mutation	c.54delG
AA Mutation	p.Thr19GlnfsTer19(p.T19Qfs*19)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	15
Mutation Consequence	stop_gained
Transcription ID	ENST00000298048
Start	36669330:36669330(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1429G>T
AA Mutation	p.Glu477Ter(p.E477*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Rectum Cancer: Gene >> MELK

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36633113:36633113(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.747G>T
AA Mutation	p.Lys249Asn(p.K249N)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000298048
Start	36665468:36665468(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1295C>T
AA Mutation	p.Ala432Val(p.A432V)
Mutation Classification	Missense_Mutation
Feature Type	Transcript