Colon Cancer: Gene >> APPL1

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57259908:57259908(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1547A>G
AA Mutation	p.Asp516Gly(p.D516G)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57248197:57248197(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs745495066
CDS Mutation	c.709C>T
AA Mutation	p.Arg237Cys(p.R237C)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57259872:57259872(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs368758377
CDS Mutation	c.1511T>C
AA Mutation	p.Val504Ala(p.V504A)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	4
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57257374:57257374(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1376C>A
AA Mutation	p.Ser459Tyr(p.S459Y)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	5
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57248312:57248312(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs748607720
CDS Mutation	c.824G>A
AA Mutation	p.Arg275Gln(p.R275Q)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	6
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57248230:57248230(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.742C>A
AA Mutation	p.Gln248Lys(p.Q248K)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	7
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57249467:57249467(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	rs746072561
CDS Mutation	c.971A>G
AA Mutation	p.Asp324Gly(p.D324G)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	8
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000288266
Start	57267789:57267789(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1890A>G
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	9
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000288266
Start	57269630:57269630(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.2073C>T
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	10
Mutation Consequence	synonymous_variant
Transcription ID	ENST00000288266
Start	57246150:57246150(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.549T>C
Mutation Classification	Silent
Feature Type	Transcript

Mutation ID	11
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000288266
Start	57237529:57237530(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	novel
CDS Mutation	c.193_194delTT
AA Mutation	p.Leu65LysfsTer4(p.L65Kfs*4)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	12
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000288266
Start	57242893:57242893(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	rs749401724
CDS Mutation	c.460delA
AA Mutation	p.Arg154GlufsTer6(p.R154Efs*6)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	13
Mutation Consequence	stop_gained
Transcription ID	ENST00000288266
Start	57259874:57259874(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1513C>T
AA Mutation	p.Arg505Ter(p.R505*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	14
Mutation Consequence	stop_gained
Transcription ID	ENST00000288266
Start	57259047:57259047(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1450G>T
AA Mutation	p.Glu484Ter(p.E484*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript

Mutation ID	15
Mutation Consequence	splice_acceptor_variant
Transcription ID	ENST00000288266
Start	57260116:57260116(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1659-1G>A
Mutation Classification	Splice_Site
Feature Type	Transcript

Mutation ID	16
Mutation Consequence	splice_donor_variant
Transcription ID	ENST00000288266
Start	57253740:57253740(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	null
CDS Mutation	c.1152+2T>C
Mutation Classification	Splice_Site
Feature Type	Transcript

Rectum Cancer: Gene >> APPL1

Mutation ID	1
Mutation Consequence	missense_variant
Transcription ID	ENST00000288266
Start	57269559:57269559(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.2002C>T
AA Mutation	p.Arg668Trp(p.R668W)
Mutation Classification	Missense_Mutation
Feature Type	Transcript

Mutation ID	2
Mutation Consequence	frameshift_variant
Transcription ID	ENST00000288266
Start	57242893:57242893(version: GRCh38)
Mutation Type	DEL
dbSNP_RS	rs749401724
CDS Mutation	c.460delA
AA Mutation	p.Arg154GlufsTer6(p.R154Efs*6)
Mutation Classification	Frame_Shift_Del
Feature Type	Transcript

Mutation ID	3
Mutation Consequence	stop_gained
Transcription ID	ENST00000288266
Start	57268482:57268482(version: GRCh38)
Mutation Type	SNP
dbSNP_RS	novel
CDS Mutation	c.1978G>T
AA Mutation	p.Glu660Ter(p.E660*)
Mutation Classification	Nonsense_Mutation
Feature Type	Transcript