Primary Site >> Liver Cancer

Gene >> ZEB2

Journal: Br J Cancer. 2004 Mar 22;90(6):1265-73.
Title: Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells.
Author: Miyoshi, A|Kitajima, Y|Sumi, K|Sato, K|Hagiwara, A|Koga, Y|Miyazaki, K
PMID: 15026811
Journal: Hepatology. 2010 Sep;52(3):945-53.
Title: Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion.
Author: Ding, Wei|You, Hanning|Dang, Hien|LeBlanc, Francis|Galicia, Vivian|Lu, Shelly C|Stiles, Bangyan|Rountree, C Bart
PMID: 20564331
Journal: Hepatology. 2011 Sep 2;54(3):879-89.
Title: c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma.
Author: You, Hanning|Ding, Wei|Dang, Hien|Jiang, Yixing|Rountree, C Bart
PMID: 21618573
Journal: Cancer Gene Ther. 2011 Sep;18(9):617-26.
Title: Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
Author: Li, T|Zeng, Z-C|Wang, L|Qiu, S-J|Zhou, J-W|Zhi, X-T|Yu, H-H|Tang, Z-Y
PMID: 21637307
Journal: BMC Cancer. 2011 Jun 6;11:223.
Title: SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation.
Author: Acun, Tolga|Oztas, Emin|Yagci, Tamer|Yakicier, Mustafa C
PMID: 21645397
Journal: J Exp Med. 2011 May 9;208(5):875-83.
Title: p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.
Author: Kim, Taewan|Veronese, Angelo|Pichiorri, Flavia|Lee, Tae Jin|Jeon, Young-Jun|Volinia, Stefano|Pineau, Pascal|Marchio, Agnes|Palatini, Jeff|Suh, Sung-Suk|Alder, Hansjuerg|Liu, Chang-Gong|Dejean, Anne|Croce, Carlo M
PMID: 21518799
Journal: Hepatology. 2012 Jun;55(6):1766-75.
Title: Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion.
Author: Grise, Florence|Sena, Sandra|Bidaud-Meynard, Aurelien|Baud, Jessica|Hiriart, Jean-Baptiste|Makki, Kassem|Dugot-Senant, Nathalie|Staedel, Cathy|Bioulac-Sage, Paulette|Zucman-Rossi, Jessica|Rosenbaum, Jean|Moreau, Violaine
PMID: 22234932
Journal: PLoS One. 2012;7(2):e32838.
Title: Overexpression of ZEB2 in peritumoral liver tissue correlates with favorable survival after curative resection of hepatocellular carcinoma.
Author: Cai, Mu-Yan|Luo, Rong-Zhen|Chen, Jie-Wei|Pei, Xiao-Qing|Lu, Jia-Bin|Hou, Jing-Hui|Yun, Jing-Ping
PMID: 22393452
Journal: Anticancer Res. 2012 Sep;32(9):3775-83.
Title: Knockdown of receptor-interacting serine/threonine protein kinase-2 (RIPK2) affects EMT-associated gene expression in human hepatoma cells.
Author: Wu, Shuang|Kanda, Tatsuo|Nakamoto, Shingo|Imazeki, Fumio|Yokosuka, Osamu
PMID: 22993319
Journal: Oncogenesis. 2012 Jun 11;1:e15.
Title: miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma.
Author: Ding, W|Dang, H|You, H|Steinway, S|Takahashi, Y|Wang, H-G|Liao, J|Stiles, B|Albert, R|Rountree, C B
PMID: 23552699
Journal: Cell Death Dis. 2013 Oct 3;4:e831.
Title: Epithelial-mesenchymal transition markers expressed in circulating tumor cells in hepatocellular carcinoma patients with different stages of disease.
Author: Li, Y-M|Xu, S-C|Li, J|Han, K-Q|Pi, H-F|Zheng, L|Zuo, G-H|Huang, X-B|Li, H-Y|Zhao, H-Z|Yu, Z-P|Zhou, Z|Liang, P
PMID: 24091674
Journal: Cancer Lett. 2013 Jan 28;328(2):198-206.
Title: Cancer genetics and genomics of human FOX family genes.
Author: Katoh, Masuko|Igarashi, Maki|Fukuda, Hirokazu|Nakagama, Hitoshi|Katoh, Masaru
PMID: 23022474
Journal: Hepatology. 2014 Mar;59(3):958-73.
Title: Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression.
Author: Xia, Limin|Huang, Wenjie|Tian, Dean|Zhang, Lin|Qi, Xingshun|Chen, Zhangqian|Shang, Xin|Nie, Yongzhan|Wu, Kaichun
PMID: 24005989
Journal: Cancer Cell. 2014 May 12;25(5):666-81.
Title: A long noncoding RNA activated by TGF-beta promotes the invasion-metastasis cascade in hepatocellular carcinoma.
Author: Yuan, Ji-hang|Yang, Fu|Wang, Fang|Ma, Jin-zhao|Guo, Ying-jun|Tao, Qi-fei|Liu, Feng|Pan, Wei|Wang, Tian-tian|Zhou, Chuan-chuan|Wang, Shao-bing|Wang, Yu-zhao|Yang, Yuan|Yang, Ning|Zhou, Wei-ping|Yang, Guang-shun|Sun, Shu-han
PMID: 24768205
Journal: Tumour Biol. 2014 Oct;35(10):9993-7.
Title: MiR-141 targets ZEB2 to suppress HCC progression.
Author: Wu, Shi-Min|Ai, Hong-Wu|Zhang, Ding-Yu|Han, Xiao-Qun|Pan, Qin|Luo, Feng-Ling|Zhang, Xiao-Lian
PMID: 25008569
Journal: Oncotarget. 2014 Nov 30;5(22):11103-20.
Title: Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma.
Author: Qi, Xiang|Ng, Kevin Tak Pan|Lian, Qi Zhou|Liu, Xiao Bing|Li, Chang Xian|Geng, Wei|Ling, Chang Chun|Ma, Yuen Yuen|Yeung, Wai Ho|Tu, Wen Wei|Fan, Sheung Tat|Lo, Chung Mau|Man, Kwan
PMID: 25333265
Journal: Oncol Rep. 2015 Dec;34(6):3272-9.
Title: miR-154 targeting ZEB2 in hepatocellular carcinoma functions as a potential tumor suppressor.
Author: Pang, Xiaoli|Huang, Kexin|Zhang, Qianqian|Zhang, Yujiao|Niu, Junqi
PMID: 26503460
Journal: Oncotarget. 2015 Nov 10;6(35):37200-15.
Title: Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.
Author: Sureban, Sripathi M|Madhoun, Mohammad F|May, Randal|Qu, Dongfeng|Ali, Naushad|Fazili, Javid|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ding, Kai|Lightfoot, Stanley A|Houchen, Courtney W
PMID: 26468984
Journal: J Transl Med. 2015 Jul 22;13:237.
Title: MRC-5 fibroblast-conditioned medium influences multiple pathways regulating invasion, migration, proliferation, and apoptosis in hepatocellular carcinoma.
Author: Ding, Songming|Chen, Guoliang|Zhang, Wu|Xing, Chunyang|Xu, Xiao|Xie, Haiyang|Lu, Aili|Chen, Kangjie|Guo, Haijun|Ren, Zhigang|Zheng, Shusen|Zhou, Lin
PMID: 26198300
Journal: Tumour Biol. 2015 Dec;36(12):9753-61.
Title: Speckle-type POZ protein is negatively associated with malignancies and inhibits cell proliferation and migration in liver cancer.
Author: Huang, Yuping|Tan, Ning|Jia, Deshui|Jing, Ying|Wang, Qifeng|Li, Zhe|Zhang, Jiwei|Liu, Li|Li, Jinjun|Chen, Zhiao|He, Xianghuo
PMID: 26156804
Journal: Oncotarget. 2015 May 10;6(13):11074-86.
Title: Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.
Author: Zhang, Sheng|Li, Jie|Liu, Pingguo|Xu, Jianfeng|Zhao, Wenxiu|Xie, Chengrong|Yin, Zhenyu|Wang, Xiaomin
PMID: 25871475
Journal: Exp Mol Pathol. 2015 Jun;98(3):352-9.
Title: ZEB2 promotes vasculogenic mimicry by TGF-beta1 induced epithelial-to-mesenchymal transition in hepatocellular carcinoma.
Author: Yang, Zhihong|Sun, Baocun|Li, Yanlei|Zhao, Xiulan|Zhao, Xueming|Gu, Qiang|An, Jindan|Dong, Xueyi|Liu, Fang|Wang, Yong
PMID: 25818166
Journal: Oncotarget. 2015 Apr 10;6(10):7918-29.
Title: MicroRNA-200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2.
Author: Yang, Xisheng|Wang, Jianlin|Qu, Shibin|Zhang, Hongtao|Ruan, Bai|Gao, Yuan|Ma, Ben|Wang, Xing|Wu, Nan|Li, Xiaolei|Dou, Kefeng|Li, Haimin
PMID: 25797260
Journal: Tumour Biol. 2015 Apr;36(4):2447-56.
Title: Overexpression of miR-200a suppresses epithelial-mesenchymal transition of liver cancer stem cells.
Author: Wang, Jianlin|Yang, Xisheng|Ruan, Bai|Dai, Bin|Gao, Yuan|Duan, Juanli|Qu, Shibin|Tao, Kaishan|Dou, Kefeng|Li, Haimin
PMID: 25412960
Journal: Biochem Biophys Res Commun. 2015 Jul 31;463(3):315-21.
Title: miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2.
Author: Qiu, Gongcai|Lin, Yujia|Zhang, Haogang|Wu, Dequan
PMID: 26022123
Journal: Oncotarget. 2016 Dec 27;7(52):86420-86432.
Title: MYC associated zinc finger protein promotes the invasion and metastasis of hepatocellular carcinoma by inducing epithelial mesenchymal transition.
Author: Luo, Wei|Zhu, Xiaonian|Liu, Wei|Ren, Yuan|Bei, Chunhua|Qin, Linyuan|Miao, Xueyan|Tang, Fen|Tang, Guifang|Tan, Shengkui
PMID: 27861158
Journal: Mol Med Rep. 2016 Nov;14(5):4606-4612.
Title: Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma.
Author: Lan, Tian|Chang, Lei|Wu, Long|Yuan, Yufeng
PMID: 27748842
Journal: Mol Immunol. 2016 Jul;75:151-60.
Title: MicroRNA-145 inhibits hepatic stellate cell activation and proliferation by targeting ZEB2 through Wnt/beta-catenin pathway.
Author: Zhou, Dan-Dan|Wang, Xiao|Wang, Yang|Xiang, Xin-Jian|Liang, Zi-Cong|Zhou, Yi|Xu, Ang|Bi, Cheng-Hao|Zhang, Lei
PMID: 27289031
Journal: Oncotarget. 2016 May 31;7(22):33246-56.
Title: Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes.
Author: Su, Yen-Hao|Huang, Wen-Chien|Huang, Tse-Hung|Huang, Yan-Jiun|Sue, Yu-Kai|Huynh, Thanh-Tuan|Hsiao, Michael|Liu, Tsan-Zon|Wu, Alexander Th|Lin, Chien-Min
PMID: 27119349
Journal: DNA Cell Biol. 2016 Aug;35(8):393-7.
Title: Evaluation of Antimetastatic Effect of lncRNA-ATB siRNA Delivered Using Ultrasound-Targeted Microbubble Destruction.
Author: Chen, Fei|Li, Yuhong|Feng, Yanhong|He, Xiuli|Wang, Liang
PMID: 27027475
Journal: Oncotarget. 2016 Mar 29;7(13):16003-11.
Title: ZEB2 inhibits HBV transcription and replication by targeting its core promoter.
Author: He, Qiao|Li, Wanyu|Ren, Jihua|Huang, Yecai|Huang, Ying|Hu, Qin|Chen, Juan|Chen, Weixian
PMID: 26895378
Journal: Int J Oncol. 2016 Apr;48(4):1639-49.
Title: Tripartite motif 16 inhibits hepatocellular carcinoma cell migration and invasion.
Author: Li, Linlin|Dong, Lei|Qu, Xiaotong|Jin, Shi|Lv, Xiupeng|Tan, Guang
PMID: 26892350
Journal: Oncotarget. 2017 Jan 3;8(1):1703-1713.
Title: FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition.
Author: Dong, Tianxiu|Zhang, Yu|Chen, Yaodong|Liu, Pengfei|An, Tingting|Zhang, Jiuwei|Yang, Haichao|Zhu, Wenjing|Yang, Xiuhua
PMID: 27924058
Journal: Biomed Pharmacother. 2017 May;89:857-863.
Title: Long non-coding RNA SNHG20 predicts a poor prognosis for HCC and promotes cell invasion by regulating the epithelial-to-mesenchymal transition.
Author: Liu, Jinxia|Lu, Cuihua|Xiao, Mingbing|Jiang, Feng|Qu, Lishuai|Ni, Runzhou
PMID: 28282787
Journal: Oncotarget. 2017 May 9;8(19):31435-31448.
Title: Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.
Author: Chen, Huihui|Lu, Wei|Huang, Chongjie|Ding, Kefeng|Xia, Dajing|Wu, Yihua|Cai, Mao
PMID: 28416756
Journal: Biomed Pharmacother. 2017 Jun;90:806-812.
Title: Regulatory role of miR-211-5p in hepatocellular carcinoma metastasis by targeting ZEB2.
Author: Jiang, Guangbin|Wen, Li|Deng, Weiping|Jian, Zhiyuan|Zheng, Hongmei
PMID: 28437884
Journal: Oncol Lett. 2017 May;13(5):3823-3830.
Title: MicroRNA-204 suppressed proliferation and motility capacity of human hepatocellular carcinoma via directly targeting zinc finger E-box binding homeobox 2.
Author: Hu, Bin|Sun, Ming|Liu, Jiajun|Hong, Guolin|Lin, Qin
PMID: 28521482
Journal: Sci Rep. 2017 Jul 5;7(1):4637.
Title: The lincRNA-ROR/miR-145 axis promotes invasion and metastasis in hepatocellular carcinoma via induction of epithelial-mesenchymal transition by targeting ZEB2.
Author: Li, Chen|Lu, Lu|Feng, Bing|Zhang, Kai|Han, Siqi|Hou, Daorong|Chen, Longbang|Chu, Xiaoyuan|Wang, Rui
PMID: 28680141
Journal: Oncotarget. 2017 Jun 2;8(35):59500-59508.
Title: Overexpression of EMT-inducing transcription factors as a potential poor prognostic factor for hepatocellular carcinoma in Asian populations: A meta-analysis.
Author: Wan, Tao|Zhang, Tianwei|Si, Xiaoying|Zhou, Yanming
PMID: 28938653
Journal: Cancer Manag Res. 2018 Mar 1;10:391-402.
Title: Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition.
Author: Liu, Jinghua|Yu, Zhen|Xiao, Yuanyuan|Meng, Qiong|Wang, Yeying|Chang, Wei
PMID: 29535552
Journal: Cell Oncol (Dordr). 2018 Aug;41(4):439-453.
Title: Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells.
Author: Karaosmanoglu, Oguzhan|Banerjee, Sreeparna|Sivas, Hulya
PMID: 29858962
Journal: Hepatology. 2018 Oct 17.
Title: NK cell-derived IFN-gamma promotes hepatocellular carcinoma through EpCAM-EMT axis in hepatitis B virus transgenic mice.
Author: Chen, Yongyan|Hao, Xiaolei|Sun, Rui|Wei, Haiming|Tian, Zhigang
PMID: 30329167