Primary Site >> Stomach Cancer

Gene >> ZEB2

Journal: Am J Pathol. 2002 Nov;161(5):1881-91.
Title: Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.
Author: Rosivatz, Erika|Becker, Ingrid|Specht, Katja|Fricke, Elena|Luber, Birgit|Busch, Raymonde|Hofler, Heinz|Becker, Karl-Friedrich
PMID: 12414534
Journal: Int J Cancer. 2004 Sep 20;111(5):711-9.
Title: Neoexpression of N-cadherin in E-cadherin positive colon cancers.
Author: Rosivatz, Erika|Becker, Ingrid|Bamba, Masamichi|Schott, Christina|Diebold, Joachim|Mayr, Doris|Hofler, Heinz|Becker, Karl-Friedrich
PMID: 15252840
Journal: Int J Oncol. 2005 Dec;27(6):1677-83.
Title: Epithelial-mesenchymal transition in gastric cancer (Review).
Author: Katoh, Masaru
PMID: 16273224
Journal: J Pathol. 2007 Apr;211(5):507-15.
Title: Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down-regulation of E-cadherin.
Author: Castro Alves, C|Rosivatz, E|Schott, C|Hollweck, R|Becker, I|Sarbia, M|Carneiro, F|Becker, K-F
PMID: 17299729
Journal: Oncogene. 2008 Apr 17;27(18):2635-47. Epub 2007 Oct 29.
Title: TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition.
Author: Jung, H|Lee, K P|Park, S J|Park, J H|Jang, Y-S|Choi, S-Y|Jung, J-G|Jo, K|Park, D Y|Yoon, J H|Park, J-H|Lim, D-S|Hong, G-R|Choi, C|Park, Y-K|Lee, J W|Hong, H J|Kim, S|Park, Y W
PMID: 17968309
Journal: Br J Cancer. 2009 Jan 27;100(2):389-98.
Title: Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers.
Author: Ohta, H|Aoyagi, K|Fukaya, M|Danjoh, I|Ohta, A|Isohata, N|Saeki, N|Taniguchi, H|Sakamoto, H|Shimoda, T|Tani, T|Yoshida, T|Sasaki, H
PMID: 19107131
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Cancer Res. 2010 Jun 1;70(11):4719-27.
Title: Downregulation of microRNA-200 in EBV-associated gastric carcinoma.
Author: Shinozaki, Aya|Sakatani, Takashi|Ushiku, Tetsuo|Hino, Rumi|Isogai, Maya|Ishikawa, Shunpei|Uozaki, Hiroshi|Takada, Kenzo|Fukayama, Masashi
PMID: 20484038
Journal: Am J Pathol. 2010 Aug;177(2):955-63.
Title: Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer.
Author: Kubota, Eiji|Kataoka, Hiromi|Aoyama, Mineyoshi|Mizoshita, Tsutomu|Mori, Yoshinori|Shimura, Takaya|Tanaka, Mamoru|Sasaki, Makoto|Takahashi, Satoru|Asai, Kiyofumi|Joh, Takashi
PMID: 20566745
Journal: Oncol Rep. 2011 May;25(5):1235-42.
Title: Vimentin expression is associated with decreased survival in gastric cancer.
Author: Otsuki, Sho|Inokuchi, Mikito|Enjoji, Megumu|Ishikawa, Toshiaki|Takagi, Yoko|Kato, Keiji|Yamada, Hiroyuki|Kojima, Kazuyuki|Sugihara, Kenichi
PMID: 21327330
Journal: Cancer Genet. 2011 Sep;204(9):486-91.
Title: miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition.
Author: Zhang, Ziping|Liu, Shaoqun|Shi, Rongliang|Zhao, Guangfa
PMID: 22018270
Journal: Ann Surg Oncol. 2012 Jul;19 Suppl 3:S656-64.
Title: MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma.
Author: Kurashige, Junji|Kamohara, Hidenobu|Watanabe, Masayuki|Hiyoshi, Yukiharu|Iwatsuki, Masaaki|Tanaka, Youhei|Kinoshita, Koichi|Saito, Seiya|Baba, Yoshifumi|Baba, Hideo
PMID: 22311119
Journal: Dig Dis Sci. 2012 May;57(5):1253-60.
Title: ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells.
Author: Dai, Ying-Huan|Tang, Ya-Ping|Zhu, Hong-Yi|Lv, Liang|Chu, Yi|Zhou, Yu-Qian|Huo, Ji-Rong
PMID: 22350782
Journal: Oncogene. 2012 Jun 21;31(25):3051-9.
Title: Smad3 regulates E-cadherin via miRNA-200 pathway.
Author: Ahn, S-M|Cha, J-Y|Kim, J|Kim, D|Trang, H T H|Kim, Y-M|Cho, Y-H|Park, D|Hong, S
PMID: 22020340
Journal: Clin Exp Metastasis. 2013 Apr;30(4):417-29.
Title: Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer.
Author: Okugawa, Yoshinaga|Inoue, Yasuhiro|Tanaka, Koji|Kawamura, Mikio|Saigusa, Susumu|Toiyama, Yuji|Ohi, Masaki|Uchida, Keiichi|Mohri, Yasuhiko|Kusunoki, Masato
PMID: 23143680
Journal: Oncol Rep. 2013 Apr;29(4):1579-87.
Title: Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/beta-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.
Author: Cong, Ningning|Du, Ping|Zhang, Anling|Shen, Fajuan|Su, Juan|Pu, Peiyu|Wang, Tao|Zjang, Jie|Kang, Chunsheng|Zhang, Qingyu
PMID: 23381389
Journal: BMC Cancer. 2014 Jan 21;14:34.
Title: MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells.
Author: Zhao, Yu|Huang, Jie|Zhang, Li|Qu, Ying|Li, Jianfang|Yu, Beiqin|Yan, Min|Yu, Yingyan|Liu, Bingya|Zhu, Zhenggang
PMID: 24443799
Journal: Cancer Genet. 2014 Mar;207(3):75-82.
Title: Down-regulation of FoxM1 leads to the inhibition of the epithelial-mesenchymal transition in gastric cancer cells.
Author: Miao, Lifeng|Xiong, Xianze|Lin, Yixin|Cheng, Yao|Lu, Jiong|Zhang, Jie|Cheng, Nansheng
PMID: 24726291
Journal: Mol Cancer. 2014 Jun 2;13:136.
Title: Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells.
Author: Li, Heming|Xu, Ling|Li, Ce|Zhao, Lei|Ma, Yanju|Zheng, Huachuan|Li, Zhi|Zhang, Ye|Wang, Ruoyu|Liu, Yunpeng|Qu, Xiujuan
PMID: 24885194
Journal: Mol Med Rep. 2014 Oct;10(4):1999-2003.
Title: Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-beta signaling pathway.
Author: Chen, Fenglin|Zhuang, Mingkai|Peng, Jun|Wang, Xiaozhong|Huang, Tingxuan|Li, Sanmei|Lin, Manqiang|Lin, Hongming|Xu, Yating|Li, Jianying|Chen, Zhixin|Huang, Yuehong
PMID: 25109410
Journal: Int J Oncol. 2014 Dec;45(6):2403-10.
Title: MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma.
Author: Minn, Yang-Ki|Lee, Da Hye|Hyung, Woo Jin|Kim, Ji Eun|Choi, Junjeong|Yang, Seung-Ho|Song, Hotaek|Lim, Beom Jin|Kim, Se Hoon
PMID: 25270520
Journal: BMC Cancer. 2014 Dec 3;14:904.
Title: Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance.
Author: Yan, Lin-Hai|Wei, Wei-Yuan|Cao, Wen-Long|Zhang, Xiao-Shi|Xie, Yu-Bo|Xiao, Qiang
PMID: 25466554
Journal: Oncol Lett. 2015 Jan;9(1):143-148.
Title: Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3beta and ZEB2 in the BGC-823 gastric cancer cell line.
Author: Li, Heming|Xu, Ling|Zhao, Lei|Ma, Yanju|Zhu, Zhitu|Liu, Yunpeng|Qu, Xiujuan
PMID: 25435948
Journal: Tumour Biol. 2015 Oct 15. pii: 10.1007/s13277-015-4094-7.
Title: MiR-429 regulates gastric cancer cell invasiveness through ZEB proteins.
Author: Liu, Wei|An, Jie|Li, Kang|Hou, Huichi
PMID: 26472725
Journal: Mol Med Rep. 2015 Sep;12(3):3416-3422.
Title: MicroRNA-141 inhibits migration of gastric cancer by targeting zinc finger E-box-binding homeobox 2.
Author: Du, Ying|Wang, Lingfei|Wu, Honghai|Zhang, Yiyin|Wang, Kan|Wu, Dingting
PMID: 25975736
Journal: Oncotarget. 2015 Jun 20;6(17):15222-34.
Title: MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling.
Author: Huang, Na|Wu, Zhenzhen|Lin, Li|Zhou, Minyu|Wang, Lin|Ma, Huanrong|Xia, Jianling|Bin, Jianping|Liao, Yulin|Liao, Wangjun
PMID: 25945841
Journal: Sheng Li Xue Bao. 2015 Feb 25;67(1):83-9.
Title: [DZNep raises miR-200c expression to delay the invasion and migration of MGC-803 gastric carcinoma cells].
Author: Ning, Xiang-Hong|Guo, Rong|Han, Lei|Zhang, An-Ling|Liu, Xi|Li, Zhao-Xia|Kang, Chun-Sheng|Zhang, Qing-Yu
PMID: 25672630
Journal: Tumour Biol. 2015 May;36(5):3621-8.
Title: Involvement of NEDD9 in the invasion and migration of gastric cancer.
Author: Feng, Jin|Zhao, Jinpeng|Xie, Haibin|Yin, Yong|Luo, Guanghua|Zhang, Jun|Feng, Yuehua|Li, Zhong
PMID: 25577245
Journal: Med Oncol. 2015 Jan;32(1):428.
Title: The downregulation of miR-200c/141 promotes ZEB1/2 expression and gastric cancer progression.
Author: Zhou, Xinliang|Wang, Yudong|Shan, Baoen|Han, Jing|Zhu, Haifeng|Lv, Yalei|Fan, Xiaojie|Sang, Meixiang|Liu, Xian-De|Liu, Wei
PMID: 25502084
Journal: Tumour Biol. 2015 Sep;36(10):7521-30.
Title: Expression of SIP1 is strongly correlated with LDHA and shows a significantly poor outcome in gastric cancer.
Author: Sun, Xuren|Sun, Zhe|Zhu, Zhi|Li, Chenyan|Zhang, Junyan|Xu, Huimian|Sun, Mingjun
PMID: 25913622
Journal: Oncotarget. 2016 May 3;7(18):25391-407.
Title: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma.
Author: Huang, Baohua|Deng, Shuo|Loo, Ser Yue|Datta, Arpita|Yap, Yan Lin|Yan, Benedict|Ooi, Chia Huey|Dinh, Thuy Duong|Zhuo, Jingli|Tochhawng, Lalchhandami|Gopinadhan, Suma|Jegadeesan, Tamilarasi|Tan, Patrick|Salto-Tellez, Manuel|Yong, Wei Peng|Soong, Richie|Yeoh
PMID: 27058427
Journal: Onco Targets Ther. 2016 Apr 18;9:2305-15.
Title: MicroRNA-145-5p inhibits gastric cancer invasiveness through targeting N-cadherin and ZEB2 to suppress epithelial-mesenchymal transition.
Author: Jiang, Shi-Bin|He, Xu-Jun|Xia, Ying-Jie|Hu, Wei-Jian|Luo, Jun-Gang|Zhang, Jun|Tao, Hou-Quan
PMID: 27143926
Journal: J Vis Exp. 2016 Aug 23;(114).
Title: An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery.
Author: Sailer, Martin H M|Sarvepalli, Durga|Bregere, Catherine|Fisch, Urs|Guentchev, Marin|Weller, Michael|Guzman, Raphael|Bettler, Bernhard|Ghosh, Arkasubhra|Hutter, Gregor
PMID: 27583933
Journal: Am J Cancer Res. 2016 Nov 1;6(11):2651-2660. eCollection 2016.
Title: Long non-coding RNA CCAT2 promotes gastric cancer proliferation and invasion by regulating the E-cadherin and LATS2.
Author: Wang, Yong-Jun|Liu, Jian-Zhen|Lv, Pei|Dang, Yi|Gao, Jiang-Yan|Wang, Yong
PMID: 27904778
Journal: Oncotarget. 2017 May 9;8(19):31435-31448.
Title: Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.
Author: Chen, Huihui|Lu, Wei|Huang, Chongjie|Ding, Kefeng|Xia, Dajing|Wu, Yihua|Cai, Mao
PMID: 28416756
Journal: Cell Physiol Biochem. 2017;42(3):1025-1036.
Title: Knockdown of ARK5 Expression Suppresses Invasion and Metastasis of Gastric Cancer.
Author: Chen, Dehu|Liu, Guiyuan|Xu, Ning|You, Xiaolan|Zhou, Haihua|Zhao, Xiaojun|Liu, Qinghong
PMID: 28662499
Journal: Oncol Rep. 2017 Jul;38(1):151-158.
Title: MicroRNA-200c regulates cisplatin resistance by targeting ZEB2 in human gastric cancer cells.
Author: Jiang, Tao|Dong, Pengfei|Li, Long|Ma, Xiao|Xu, Pei|Zhu, He|Wang, Yanqiu|Yang, Baotong|Liu, Kuangge|Liu, Jinwei|Xue, Juan|Lv, Runzhe|Su, Panke|Kong, Guoqiang|Chang, Yongchao|Zhao, Chonggao|Wang, Lidong
PMID: 28534959
Journal: Eur Rev Med Pharmacol Sci. 2017 Apr;21(8):1746-1752.
Title: Effect of ZEB2 silencing on cisplatin resistance in gastric cancer.
Author: Geng, D-M|Kan, X-M|Zhang, W-W
PMID: 28485807
Journal: Oncol Res. 2017 Nov 2;25(9):1453-1462.
Title: Basic Transcription Factor 3 Is Required for Proliferation and Epithelial-Mesenchymal Transition via Regulation of FOXM1 and JAK2/STAT3 Signaling in Gastric Cancer.
Author: Zhang, De-Zhong|Chen, Bing-He|Zhang, Lan-Fang|Cheng, Ming-Kun|Fang, Xiang-Jie|Wu, Xin-Jun
PMID: 28276310
Journal: J Cancer Res Clin Oncol. 2017 Mar;143(3):385-397.
Title: HOXB8 promotes tumor metastasis and the epithelial-mesenchymal transition via ZEB2 targets in gastric cancer.
Author: Ding, Wen-Jin|Zhou, Min|Chen, Mei-Mei|Qu, Chun-Ying
PMID: 27761656
Journal: Cell Biol Int. 2018 Mar;42(3):294-302.
Title: Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.
Author: Zhao, Lei|Li, Xin|Song, Na|Li, Aodi|Hou, Kezuo|Qu, Xiujuan|Che, Xiaofang|Liu, Yunpeng
PMID: 29052277
Journal: Cancer Gene Ther. 2018 May;25(3-4):68-76.
Title: miR-200c inhibits TGF-beta-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer.
Author: Zhou, Xinliang|Men, Xinyi|Zhao, Riyang|Han, Jing|Fan, Zhisong|Wang, Yudong|Lv, Yalei|Zuo, Jing|Zhao, Lianmei|Sang, Meixiang|Liu, Xian-De|Shan, Baoen
PMID: 29302045
Journal: Mol Carcinog. 2018 Jul;57(7):947-954.
Title: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice.
Author: Park, Jun Won|Kim, Min-Sik|Voon, Dominic C|Kim, Su-Jin|Bae, Jingi|Mun, Dong-Gi|Ko, Seung-Ik|Kim, Hark K|Lee, Sang-Won|Kim, Dae-Yong
PMID: 29528141
Journal: Onco Targets Ther. 2018 Apr 27;11:2363-2373.
Title: LDH-Apromotes epithelial-mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer.
Author: Zhang, Yongjie|Lin, Sen|Chen, Yan|Yang, Fei|Liu, Shenlin
PMID: 29740212
Journal: Pathobiology. 2018;85(4):232-246.
Title: MicroRNAs Associated with Epithelial-Mesenchymal Transition Can Be Targeted to Inhibit Peritoneal Dissemination of Human Scirrhous Gastric Cancers.
Author: Takei, Yoshifumi|Shen, Guodong|Morita-Kondo, Ayami|Hara, Toshifumi|Mihara, Keichiro|Yanagihara, Kazuyoshi
PMID: 29847827
Journal: Anticancer Res. 2018 Jul;38(7):3871-3877.
Title: Polymorphisms in TWIST1 and ZEB1 Are Associated with Prognosis of Gastric Cancer Patients.
Author: Romero, Sandra|Musleh, Maher|Bustamante, Marco|Stambuk, Juan|Pisano, Raul|Lanzarini, Enrique|Chiong, Hector|Rojas, Jorge|Castro, V Gonzalo|Jara, Lilian|Berger, Zoltan|Gonzalez-Hormazabal, Patricio
PMID: 29970507