Primary Site >> Colorectal Cancer

Gene >> ZEB2

Journal: Int J Cancer. 2004 Sep 20;111(5):711-9.
Title: Neoexpression of N-cadherin in E-cadherin positive colon cancers.
Author: Rosivatz, Erika|Becker, Ingrid|Bamba, Masamichi|Schott, Christina|Diebold, Joachim|Mayr, Doris|Hofler, Heinz|Becker, Karl-Friedrich
PMID: 15252840
Journal: Oncogene. 2008 Apr 17;27(18):2635-47. Epub 2007 Oct 29.
Title: TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition.
Author: Jung, H|Lee, K P|Park, S J|Park, J H|Jang, Y-S|Choi, S-Y|Jung, J-G|Jo, K|Park, D Y|Yoon, J H|Park, J-H|Lim, D-S|Hong, G-R|Choi, C|Park, Y-K|Lee, J W|Hong, H J|Kim, S|Park, Y W
PMID: 17968309
Journal: J Clin Invest. 2009 Aug;119(8):2343-58.
Title: Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.
Author: Alvarez-Diaz, Silvia|Valle, Noelia|Garcia, Jose Miguel|Pena, Cristina|Freije, Jose M P|Quesada, Victor|Astudillo, Aurora|Bonilla, Felix|Lopez-Otin, Carlos|Munoz, Alberto
PMID: 19662683
Journal: Carcinogenesis. 2009 Aug;30(8):1459-68.
Title: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.
Author: Larriba, Maria Jesus|Martin-Villar, Ester|Garcia, Jose Miguel|Pereira, Fabio|Pena, Cristina|de Herreros, Antonio Garcia|Bonilla, Felix|Munoz, Alberto
PMID: 19502595
Journal: Dig Dis Sci. 2010 Aug;55(8):2365-72.
Title: MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells.
Author: Hu, Minghua|Xia, MicroGene|Chen, Xiaobing|Lin, Zihong|Xu, Yajun|Ma, Yuedong|Su, Lei
PMID: 19830559
Journal: J Nanobiotechnology. 2011 Sep 19;9:40.
Title: Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
Author: Sureban, Sripathi M|May, Randal|Mondalek, Fadee G|Qu, Dongfeng|Ponnurangam, Sivapriya|Pantazis, Panayotis|Anant, Shrikant|Ramanujam, Rama P|Houchen, Courtney W
PMID: 21929751
Journal: Clin Cancer Res. 2011 Dec 15;17(24):7654-63.
Title: Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro.
Author: Kahlert, Christoph|Lahes, Saleh|Radhakrishnan, Praveen|Dutta, Shamik|Mogler, Carolin|Herpel, Esther|Brand, Karsten|Steinert, Gunnar|Schneider, Martin|Mollenhauer, Martin|Reissfelder, Christoph|Klupp, Fee|Fritzmann, Johannes|Wunder, Christina|Benner, Axel|
PMID: 22042972
Journal: Oncogene. 2012 Apr 19;31(16):2062-74.
Title: Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis.
Author: Davalos, V|Moutinho, C|Villanueva, A|Boque, R|Silva, P|Carneiro, F|Esteller, M
PMID: 21874049
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Dec;15(12):1318-21.
Title: [Competing endogenous RNA regulation mechanism and its role in the development and progression of colorectal cancer].
Author: Gao, Xian-hua|Fu, Chuan-gang|Lao, Xin-yuan|Tan, Zhu-jun
PMID: 23596669
Journal: Surg Today. 2013 Jan;43(1):73-80.
Title: Differences in the expression of epithelial-mesenchymal transition related molecules between primary tumors and pulmonary metastatic tumors in colorectal cancer.
Author: Kouso, Hidenori|Yano, Tokujiro|Maruyama, Riichiroh|Shikada, Yasunori|Okamoto, Tatsuro|Haro, Akira|Kakeji, Yoshihiro|Maehara, Yoshihiko
PMID: 23052737
Journal: PLoS One. 2013;8(1):e54211.
Title: TAZ expression as a prognostic indicator in colorectal cancer.
Author: Yuen, Hiu-Fung|McCrudden, Cian M|Huang, Yu-Han|Tham, Jill M|Zhang, Xiaoqian|Zeng, Qi|Zhang, Shu-Dong|Hong, WanJin
PMID: 23372686
Journal: Neoplasia. 2013 Feb;15(2):180-91.
Title: Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression.
Author: Paterson, Emily L|Kazenwadel, Jan|Bert, Andrew G|Khew-Goodall, Yeesim|Ruszkiewicz, Andrew|Goodall, Gregory J
PMID: 23441132
Journal: Carcinogenesis. 2014 Feb;35(2):302-14.
Title: ZEB2-Sp1 cooperation induces invasion by upregulating cadherin-11 and integrin alpha5 expression.
Author: Nam, Eun-Hee|Lee, Yunhee|Zhao, Xue-Feng|Park, Young-Kyu|Lee, Jung Weon|Kim, Semi
PMID: 24130169
Journal: Biomed Res Int. 2014;2014:629496.
Title: Epithelial-mesenchymal transition and somatic alteration in colorectal cancer with and without peritoneal carcinomatosis.
Author: Shelygin, Y A|Pospekhova, N I|Shubin, V P|Kashnikov, V N|Frolov, S A|Sushkov, O I|Achkasov, S I|Tsukanov, A S
PMID: 25157365
Journal:
Title: miR-132 inhibits colorectal cancer invasion and metastasis via directly targeting ZEB2.
Author:
PMID: 24914372
Journal: Med Oncol. 2014 Jun;31(6):982.
Title: MicroRNA-335 inhibits invasion and metastasis of colorectal cancer by targeting ZEB2.
Author: Sun, ZhiFeng|Zhang, Zhang|Liu, Zidong|Qiu, Bo|Liu, Kan|Dong, Guanglong
PMID: 24829139
Journal: World J Gastroenterol. 2014 Jun 7;20(21):6515-22.
Title: miR-132 inhibits colorectal cancer invasion and metastasis via directly targeting ZEB2.
Author: Zheng, Yong-Bin|Luo, Hai-Ping|Shi, Qiang|Hao, Zhi-Nan|Ding, Yu|Wang, Qiu-Shuang|Li, Sheng-Bo|Xiao, Gao-Chun|Tong, Shi-Lun
PMID: 24781162
Journal: PLoS One. 2014 Apr 23;9(4):e94621.
Title: Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells.
Author: Sahlberg, Sara Haggblad|Spiegelberg, Diana|Glimelius, Bengt|Stenerlow, Bo|Nestor, Marika
PMID: 24760019
Journal: Mol Cell Biochem. 2014 May;390(1-2):19-30.
Title: MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma.
Author: Sun, Yingnan|Shen, Shourong|Liu, Xiaoping|Tang, Hailin|Wang, Zeyou|Yu, Zhibin|Li, Xiayu|Wu, Minghua
PMID: 24402783
Journal: Oncogene. 2014 Nov 13;33(46):5332-40.
Title: MicroRNA-192 suppresses liver metastasis of colon cancer.
Author: Geng, L|Chaudhuri, A|Talmon, G|Wisecarver, J L|Are, C|Brattain, M|Wang, J
PMID: 24213572
Journal: Toxicol Res. 2015 Jun;31(2):151-6.
Title: Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells.
Author: Kim, A-Young|Kwak, Jae-Hwan|Je, Nam Kyung|Lee, Yun-Hee|Jung, Young-Suk
PMID: 26191381
Journal: Int J Clin Exp Pathol. 2015 May 1;8(5):4481-91. eCollection 2015.
Title: Up-regulation of microRNA-302a inhibited the proliferation and invasion of colorectal cancer cells by regulation of the MAPK and PI3K/Akt signaling pathways.
Author: Wei, Zhi-Jiang|Tao, Ming-Ling|Zhang, Wei|Han, Guo-Da|Zhu, Zhong-Cheng|Miao, Zhi-Gang|Li, Jian-Ye|Qiao, Zhan-Bing
PMID: 26191138
Journal: Oncotarget. 2015 Sep 8;6(26):22513-25.
Title: The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer.
Author: Liang, Wei-Cheng|Fu, Wei-Ming|Wong, Cheuk-Wa|Wang, Yan|Wang, Wei-Mao|Hu, Guo-Xin|Zhang, Li|Xiao, Li-Jia|Wan, David Chi-Cheong|Zhang, Jin-Fang|Waye, Mary Miu-Yee
PMID: 26068968
Journal: Int J Oncol. 2015 Feb;46(2):685-90.
Title: Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-beta1/ZEB/miR-200 signaling network.
Author: Shen, Aling|Lin, Wei|Chen, Youqin|Liu, Liya|Chen, Hongwei|Zhuang, Qunchuan|Lin, Jiumao|Sferra, Thomas J|Peng, Jun
PMID: 25422078
Journal: Oncotarget. 2015 Jun 20;6(17):15222-34.
Title: MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling.
Author: Huang, Na|Wu, Zhenzhen|Lin, Li|Zhou, Minyu|Wang, Lin|Ma, Huanrong|Xia, Jianling|Bin, Jianping|Liao, Yulin|Liao, Wangjun
PMID: 25945841
Journal: Oncogene. 2016 Oct 6;35(40):5263-5271.
Title: Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.
Author: Vellinga, T T|den Uil, S|Rinkes, I H B|Marvin, D|Ponsioen, B|Alvarez-Varela, A|Fatrai, S|Scheele, C|Zwijnenburg, D A|Snippert, H|Vermeulen, L|Medema, J P|Stockmann, H B|Koster, J|Fijneman, R J A|de Rooij, J|Kranenburg, O
PMID: 26996663
Journal: Biochem Biophys Res Commun. 2016 Sep 2;477(4):801-806.
Title: Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation.
Author: Tashiro, Etsu|Henmi, Shizuka|Odake, Hiroyuki|Ino, Seitaro|Imoto, Masaya
PMID: 27369075
Journal: Adv Exp Med Biol. 2016;937:71-92.
Title: Interplay Between Transcription Factors and MicroRNAs Regulating Epithelial-Mesenchymal Transitions in Colorectal Cancer.
Author: Kaller, Markus|Hermeking, Heiko
PMID: 27573895
Journal: J Vis Exp. 2016 Aug 23;(114).
Title: An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery.
Author: Sailer, Martin H M|Sarvepalli, Durga|Bregere, Catherine|Fisch, Urs|Guentchev, Marin|Weller, Michael|Guzman, Raphael|Bettler, Bernhard|Ghosh, Arkasubhra|Hutter, Gregor
PMID: 27583933
Journal: Oncol Rep. 2016 Nov;36(5):3065-3071.
Title: Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in vitro.
Author: Holzner, Silvio|Senfter, Daniel|Stadler, Serena|Staribacher, Anna|Nguyen, Chi Huu|Gaggl, Anna|Geleff, Silvana|Huttary, Nicole|Krieger, Sigurd|Jager, Walter|Dolznig, Helmut|Mader, Robert M|Krupitza, Georg
PMID: 27666412
Journal: Am J Transl Res. 2017 Jun 15;9(6):2838-2851. eCollection 2017.
Title: ZEB2 promotes tumor metastasis and correlates with poor prognosis of human colorectal cancer.
Author: Li, Ming-Zhe|Wang, Jing-Jing|Yang, Shi-Bin|Li, Wen-Feng|Xiao, Long-Bin|He, Yu-Long|Song, Xin-Ming
PMID: 28670373
Journal: Cancers (Basel). 2017 Dec 16;9(12). pii: cancers9120171.
Title: Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis.
Author: Vu, Trung|Datta, Pran K
PMID: 29258163
Journal: BMC Cancer. 2017 Dec 4;17(1):813.
Title: Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-kappaB/slug/E-cadherin pathway.
Author: Zhou, Panpan|Wang, Chunling|Hu, Zebin|Chen, Wenruo|Qi, Wentao|Li, Aike
PMID: 29202800
Journal: Theranostics. 2017 Oct 17;7(19):4836-4849.
Title: Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression.
Author: Chen, Dong-Liang|Lu, Yun-Xin|Zhang, Jia-Xing|Wei, Xiao-Li|Wang, Feng|Zeng, Zhao-Lei|Pan, Zhi-Zhong|Yuan, Yun-Fei|Wang, Feng-Hua|Pelicano, Helene|Chiao, Paul J|Huang, Peng|Xie, Dan|Li, Yu-Hong|Ju, Huai-Qiang|Xu, Rui-Hua
PMID: 29187907
Journal: Anticancer Res. 2017 Aug;37(8):4345-4352.
Title: miR-141 Inhibits Proliferation and Migration of Colorectal Cancer SW480 Cells.
Author: Long, Zhi H|Bai, Zhi G|Song, Jian N|Zheng, Zhi|Li, Jun|Zhang, Jun|Cai, Jun|Yao, Hong W|Wang, Jin|Yang, Ying C|Yin, Jie|Zhang, Zhong T
PMID: 28739727
Journal: Eur Rev Med Pharmacol Sci. 2017 May;21(10):2357-2363.
Title: Correlation analysis of miR-200b, miR-200c, and miR-141 with liver metastases in colorectal cancer patients.
Author: Zhu, S-H|He, X-C|Wang, L
PMID: 28617555
Journal: Int J Mol Sci. 2017 Jun 13;18(6). pii: ijms18061265.
Title: Predicting Outcome and Therapy Response in mCRC Patients Using an Indirect Method for CTCs Detection by a Multigene Expression Panel: A Multicentric Prospective Validation Study.
Author: Insua, Yolanda Vidal|Camara, Juan de la|Vazquez, Elena Brozos|Fernandez, Ana|Rivera, Francisca Vazquez|Silva, M feminine Jose Villanueva Villanueva|Barbazan, Jorge|Muinelo-Romay, Laura|Folgar, Sonia Candamio|Abalo, Alicia|Lopez-Lopez, Rafael|Abal, Miguel|
PMID: 28608814
Journal: Sci Rep. 2017 May 4;7:46078.
Title: RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC.
Author: Wang, Xiao-Yan|Li, Sheng-Nan|Zhu, Hui-Fang|Hu, Zhi-Yan|Zhong, Yan|Gu, Chuan-Sha|Chen, Shi-You|Liu, Teng-Fei|Li, Zu-Guo
PMID: 28470188
Journal: Oncotarget. 2017 May 9;8(19):31435-31448.
Title: Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.
Author: Chen, Huihui|Lu, Wei|Huang, Chongjie|Ding, Kefeng|Xia, Dajing|Wu, Yihua|Cai, Mao
PMID: 28416756
Journal: J Cell Biochem. 2018 Feb;119(2):2022-2035.
Title: microRNA-145 downregulates SIP1-expression but differentially regulates proliferation, migration, invasion and Wnt signaling in SW480 and SW620 cells.
Author: Sathyanarayanan, Anusha|Chandrasekaran, Karthik Subramanian|Karunagaran, Devarajan
PMID: 28833449
Journal: BMC Genomics. 2018 Feb 9;19(Suppl 3):113.
Title: HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer.
Author: Pudova, Elena A|Kudryavtseva, Anna V|Fedorova, Maria S|Zaretsky, Andrew R|Shcherbo, Dmitry S|Lukyanova, Elena N|Popov, Anatoly Y|Sadritdinova, Asiya F|Abramov, Ivan S|Kharitonov, Sergey L|Krasnov, George S|Klimina, Kseniya M|Koroban, Nadezhda V|Volchenko,
PMID: 29504907
Journal: Cell Oncol (Dordr). 2018 Aug;41(4):379-393.
Title: Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors.
Author: Balcik-Ercin, Pelin|Cetin, Metin|Yalim-Camci, Irem|Odabas, Gorkem|Tokay, Nurettin|Sayan, A Emre|Yagci, Tamer
PMID: 29516288
Journal: Oncol Lett. 2018 Jun;15(6):9413-9419.
Title: Screening for susceptibility genes in hereditary non-polyposis colorectal cancer.
Author: Yu, Li|Yin, Bo|Qu, Kaiying|Li, Jingjing|Jin, Qiao|Liu, Ling|Liu, Chunlan|Zhu, Yuxing|Wang, Qi|Peng, Xiaowei|Zhou, Jianda|Cao, Peiguo|Cao, Ke
PMID: 29844832
Journal: Int J Oncol. 2018 Aug;53(2):567-578.
Title: E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells.
Author: Chen, Jiaoe|Gong, Chaoju|Mao, Huiqin|Li, Zhaoyun|Fang, Zejun|Chen, Qiang|Lin, Min|Jiang, Xiang|Hu, Yanyan|Wang, Wei|Zhang, Xiaomin|Chen, Xianjun|Li, Hongzhang
PMID: 29901191
Journal: Mod Pathol. 2018 Sep 11. pii: 10.1038/s41379-018-0124-5.
Title: Low miR200c expression in tumor budding of invasive front predicts worse survival in patients with localized colon cancer and is related to PD-L1 overexpression.
Author: Martinez-Ciarpaglini, Carolina|Oltra, Sara|Rosello, Susana|Roda, Desamparados|Mongort, Cristina|Carrasco, Francisca|Gonzalez, Jose|Santonja, Francisco|Tarazona, Noelia|Huerta, Marisol|Espi, Alejandro|Ribas, Gloria|Ferrandez, Antonio|Navarro, Samuel|Cervan
PMID: 30206410