Primary Site >> Biliary tract Cancer

Gene >> VEGFC

Journal: Int J Mol Med. 2003 Jan;11(1):33-9.
Title: Vascular endothelial growth factor-C expression in human gallbladder cancer and its relationship to lymph node metastasis.
Author: Nakashima, Tetsuya|Kondoh, Satoshi|Kitoh, Hideaki|Ozawa, Hirokazu|Okita, Satoshi|Harada, Tomohiko|Shiraishi, Kei|Ryozawa, Shomei|Okita, Kiwamu
PMID: 12469214
Journal: Cancer Res. 2005 Dec 15;65(24):11437-46.
Title: gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway.
Author: Fava, Giammarco|Marucci, Luca|Glaser, Shannon|Francis, Heather|De Morrow, Sharon|Benedetti, Antonio|Alvaro, Domenico|Venter, Julie|Meininger, Cynthia|Patel, Tushar|Taffetani, Silvia|Marzioni, Marco|Summers, Ryun|Reichenbach, Ramona|Alpini, Gianfranco
PMID: 16357152
Journal: Am J Clin Oncol. 2006 Apr;29(2):138-42.
Title: The clinicopathologic significance of the expression of vascular endothelial growth factor-C in intrahepatic cholangiocarcinoma.
Author: Park, Byung Kyu|Paik, Yong-Han|Park, Jeong Youp|Park, Kyung Hwa|Bang, Seungmin|Park, Seung Woo|Chung, Jae Bock|Park, Young Nyun|Song, Si Young
PMID: 16601431
Journal: World J Gastroenterol. 2006 Apr 28;12(16):2549-55.
Title: Impact of lymph node micrometastasis in hilar bile duct carcinoma patients.
Author: Taniguchi, Kentaro|Iida, Taku|Hori, Tomohide|Yagi, Shintaro|Imai, Hiroshi|Shiraishi, Taizo|Uemoto, Shinji
PMID: 16688800
Journal: Mod Pathol. 2008 Mar;21(3):256-64.
Title: Lymphatic spread is related to VEGF-C expression and D2-40-positive myofibroblasts in intrahepatic cholangiocarcinoma.
Author: Aishima, Shinichi|Nishihara, Yunosuke|Iguchi, Tomohiro|Taguchi, Kenichi|Taketomi, Akinobu|Maehara, Yoshihiko|Tsuneyoshi, Masazumi
PMID: 18192971
Journal: Dig Liver Dis. 2009 Feb;41(2):156-63.
Title: Estrogens stimulate the proliferation of human cholangiocarcinoma by inducing the expression and secretion of vascular endothelial growth factor.
Author: Mancino, A|Mancino, M G|Glaser, S S|Alpini, G|Bolognese, A|Izzo, L|Francis, H|Onori, P|Franchitto, A|Ginanni-Corradini, S|Gaudio, E|Alvaro, D
PMID: 18395502
Journal: Liver Int. 2009 Aug;29(7):1031-42.
Title: Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression.
Author: Fava, Giammarco|Demorrow, Sharon|Gaudio, Eugenio|Franchitto, Antonio|Onori, Paolo|Carpino, Guido|Glaser, Shannon|Francis, Heather|Coufal, Monique|Marucci, Luca|Alvaro, Domenico|Marzioni, Marco|Horst, Trenton|Mancinelli, Romina|Benedetti, Antonio|Alpini, G
PMID: 19291182
Journal: Mol Cancer Res. 2009 Oct;7(10):1704-13.
Title: H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
Author: Francis, Heather|Onori, Paolo|Gaudio, Eugenio|Franchitto, Antonio|DeMorrow, Sharon|Venter, Julie|Kopriva, Shelley|Carpino, Guido|Mancinelli, Romina|White, Mellanie|Meng, Fanyin|Vetuschi, Antonella|Sferra, Roberta|Alpini, Gianfranco
PMID: 19825989
Journal: Zhonghua Zhong Liu Za Zhi. 2009 Oct;31(10):773-7.
Title: [Correlation between PPARgamma and VEGF-C expression in extrahepatic cholangioadenocarcinoma (EHCAC) and their prognostic significance].
Author: Wang, Wen-bin|Li, Yue-hong|Liu, Bing|Wang, Heng-shu|Cui, Ai-rong|Zhnag, Xiang-hong
PMID: 20021832
Journal: World J Surg. 2010 May;34(5):1039-45.
Title: Nerve growth factor-beta expression is associated with lymph node metastasis and nerve infiltration in human hilar cholangiocarcinoma.
Author: Xu, Lei-Bo|Liu, Chao|Gao, Guo-Quan|Yu, Xian-Huan|Zhang, Rui|Wang, Jie
PMID: 20119692
Journal: Zhonghua Zhong Liu Za Zhi. 2010 Mar;32(3):190-5.
Title: [Expressions of VEGF-C and VEGF-D and their correlation with lymphangiogenesis and angiogenesis in gallbladder carcinoma].
Author: Jiang, Lei|Chen, Yan-ling|She, Fei-fei|Tang, Nan-hong|Li, Xiu-jin|Wang, Xiao-xi
PMID: 20450586
Journal: Mol Cell Biochem. 2010 Dec;345(1-2):77-89.
Title: Vascular endothelial growth factor-C promotes the growth and invasion of gallbladder cancer via an autocrine mechanism.
Author: Chen, Yanling|Jiang, Lei|She, Feifei|Tang, Nanhong|Wang, Xiaoqian|Li, Xiujin|Han, Shenghua|Zhu, Jinhai
PMID: 20734221
Journal: Cancer. 2013 Mar 1;119(5):993-1003.
Title: High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery.
Author: Shi, Ruo-Yu|Yang, Xin-Rong|Shen, Qiu-Jin|Yang, Liu-Xiao|Xu, Yang|Qiu, Shuang-Jian|Sun, Yun-Fan|Zhang, Xin|Wang, Zheng|Zhu, Kai|Qin, Wen-Xin|Tang, Zhao-You|Fan, Jia|Zhou, Jian
PMID: 23132676
Journal: Hum Pathol. 2013 Jun;44(6):1031-7.
Title: Different roles of inducible nitric oxide synthase and cyclooxygenase-2 in carcinogenesis and metastasis of intrahepatic cholangiocarcinoma.
Author: Aishima, Shinichi|Mano, Yohei|Tanaka, Yuki|Kubo, Yuichiro|Shirabe, Ken|Maehara, Yoshihiko|Oda, Yoshinao
PMID: 23260331
Journal: PLoS One. 2013 Apr 24;8(4):e62024.
Title: Over-expression of nerve growth factor-beta in human cholangiocarcinoma QBC939 cells promote tumor progression.
Author: Yue, Xiu-Jing|Xu, Lei-Bo|Zhu, Man-Sheng|Zhang, Rui|Liu, Chao
PMID: 23637956
Journal: Scand J Gastroenterol. 2013 Jul;48(7):848-55.
Title: Quantitative analysis of VEGF-C mRNA of extrahepatic cholangiocarcinoma with real-time PCR using samples obtained during endoscopic retrograde cholangiopancreatography.
Author: Dobashi, Akira|Imazu, Hiroo|Tatsumi, Norifumi|Okabe, Masataka|Ang, Tiing Leong|Tajiri, Hisao
PMID: 23721191
Journal: Cancer Sci. 2014 Oct;105(10):1261-71.
Title: Tumor necrosis factor-alpha promotes the lymphangiogenesis of gallbladder carcinoma through nuclear factor-kappaB-mediated upregulation of vascular endothelial growth factor-C.
Author: Du, Qiang|Jiang, Lei|Wang, Xiaoqian|Wang, Meiping|She, Feifei|Chen, Yanling
PMID: 25154789
Journal: Cell Physiol Biochem. 2014;34(4):1152-65.
Title: Expression of the RIP-1 gene and its role in growth and invasion of human gallbladder carcinoma.
Author: Zhu, Guangwei|Chen, Xiao|Wang, Xiaoqian|Li, Xiujin|Du, Qiang|Hong, Haijie|Tang, Nanhong|She, Feifei|Chen, Yanling
PMID: 25277242
Journal: Tumour Biol. 2015 Aug;36(8):6305-12.
Title: Serum vascular endothelial growth factors C and D as forecast tools for patients with gallbladder carcinoma.
Author: Liu, Min-Chao|Jiang, Lei|Hong, Hai-Jie|Meng, Ze-Wu|Du, Qiang|Zhou, Liang-Yi|She, Fei-Fei|Chen, Yan-Ling
PMID: 25801241
Journal: World J Gastroenterol. 2015 Mar 21;21(11):3256-65.
Title: High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma.
Author: Xu, Yun-Fei|Ge, Fu-Jun|Han, Bo|Yang, Xiao-Qing|Su, Hong|Zhao, An-Cheng|Zhao, Ming-Hong|Yang, Yu-Bao|Yang, Jie
PMID: 25805932
Journal: Mol Med Rep. 2015 Nov;12(5):7079-85.
Title: MicroRNA-101 inhibits the migration and invasion of intrahepatic cholangiocarcinoma cells via direct suppression of vascular endothelial growth factor-C.
Author: Deng, Gang|Teng, Yinglu|Huang, Feizhou|Nie, Wanpin|Zhu, Lei|Huang, Wei|Xu, Hongbo
PMID: 26299768
Journal: Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1;309(11):G865-73.
Title: Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors.
Author: Mancinelli, Romina|Glaser, Shannon|Francis, Heather|Carpino, Guido|Franchitto, Antonio|Vetuschi, Antonella|Sferra, Roberta|Pannarale, Luigi|Venter, Julie|Meng, Fanyin|Alpini, Gianfranco|Onori, Paolo|Gaudio, Eugenio
PMID: 26451003
Journal: Chin Med Sci J. 2015 Dec;30(4):252-9.
Title: Influence of Photodynamic Therapy on Apoptosis and Invasion of Human Cholangiocarcinoma QBC939 Cell Line.
Author: Chen, Yun-jie|Jiang, Hai-tao|Cao, Jing-yu
PMID: 26960307
Journal: Int J Oncol. 2016 Jul;49(1):197-206.
Title: Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor.
Author: Zou, Hao|Liu, Yunxia|Wei, Dong|Wang, Tao|Wang, Kun|Huang, Songquan|Liu, Lixin|Li, Yuehua|Ge, Jiayun|Li, Xiao|Zhu, Hong|Wang, Lianmin|Zhao, Songling|Zhang, Xiaowen|Wang, Lin
PMID: 27211817
Journal: Asian Pac J Cancer Prev. 2016;17(4):2151-7.
Title: Scabraside D Derived from Sea Cucumber Induces Apoptosis and Inhibits Metastasis via iNOS and STAT-3 Expression in Human Cholangiocarcinoma Xenografts.
Author: Assawasuparerk, Kanjana|Rawangchue, Thanakorn|Phonarknguen, Rassameepen
PMID: 27221911
Journal: J Biol Regul Homeost Agents. 2017 Jan-Mar;31(1):51-58.
Title: JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling.
Author: Fu, L X|Lian, Q W|Pan, J D|Xu, Z L|Zhou, T M|Ye, B
PMID: 28337870
Journal: Oncotarget. 2017 May 30;8(22):36211-36224.
Title: Tropomyosin-related kinase B mediated signaling contributes to the induction of malignant phenotype of gallbladder cancer.
Author: Kawamoto, Makoto|Onishi, Hideya|Ozono, Keigo|Yamasaki, Akio|Imaizumi, Akira|Kamakura, Sachiko|Nakano, Kenji|Oda, Yoshinao|Sumimoto, Hideki|Nakamura, Masafumi
PMID: 28423707
Journal: Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title: Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
Author: Papadopoulou, Kyriaki|Murray, Samuel|Manousou, Kyriaki|Tikas, Ioannis|Dervenis, Christos|Sgouros, Joseph|Rontogianni, Dimitra|Lakis, Sotirios|Bobos, Mattheos|Poulios, Christos|Pervana, Stavroula|Lazaridis, Georgios|Fountzilas, George|Kotoula, Vassiliki
PMID: 29416916
Journal: Onco Targets Ther. 2018 May 16;11:2875-2890.
Title: RIP1 regulates TNF-alpha-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-kappaB-VEGF-C pathway.
Author: Li, Cheng-Zong|Jiang, Xiao-Jie|Lin, Bin|Hong, Hai-Jie|Zhu, Si-Yuan|Jiang, Lei|Wang, Xiao-Qian|Tang, Nan-Hong|She, Fei-Fei|Chen, Yan-Ling
PMID: 29844685
Journal: Br J Cancer. 2018 Jul;119(1):27-35.
Title: Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial.
Author: Backen, Alison C|Lopes, Andre|Wasan, Harpreet|Palmer, Daniel H|Duggan, Marian|Cunningham, David|Anthoney, Alan|Corrie, Pippa G|Madhusudan, Srinivasan|Maraveyas, Anthony|Ross, Paul J|Waters, Justin S|Steward, William P|Rees, Charlotte|McNamara, Mairead G|B
PMID: 29925934
Journal: Oncol Lett. 2018 Aug;16(2):1841-1848.
Title: Inhibiting the proliferation and metastasis of hilar cholangiocarcinoma cells by blocking the expression of vascular endothelial growth factor with small interfering RNA.
Author: Xiao, Ke|Ouyang, Zhengxiao|Tang, Hui-Huan
PMID: 30008874
Journal: Oncol Lett. 2018 Nov;16(5):6065-6070.
Title: Serum vascular endothelial growth factor-C levels predict lymph node metastasis and prognosis of patients with gallbladder cancer.
Author: Jiang, Lei|Liu, Minchao|Cai, Xinran|Xie, Lijun|She, Feifei|Chen, Yanling
PMID: 30344750