Literatures

Primary Site >> Colorectal Cancer

Gene >> UMPS

1.
Journal:	Cancer Res. 1986 Jan;46(1):20-8.
Title:	Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes.
Author:	Peters, G J\|Laurensse, E\|Leyva, A\|Lankelma, J\|Pinedo, H M
PMID:	2415245

2.
Journal:	Gan To Kagaku Ryoho. 2000 Aug;27(9):1415-20.
Title:	[Analysis of the salvage synthesis within biosynthesis of nucleic acid route in colon cancer].
Author:	Katsumata, K\|Sumi, T\|Murohashi, T\|Nagashima, K\|Uda, O\|Ashizawa, T\|Yamamoto, K\|Koyanagi, Y
PMID:	10969598

3.
Journal:	Gan To Kagaku Ryoho. 2001 May;28(5):661-7.
Title:	[Correlation between 5-fluorouracil (5-FU) sensitivity as measured by collagen gel droplet embedded culture drug sensitivity test (CD-DST) and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydr
Author:	Ochiai, T\|Sugitani, M\|Nishimura, K\|Noguchi, H\|Watanabe, T\|Sengoku, H\|Kihara, A\|Okano, M
PMID:	11383215

4.
Journal:	Gan To Kagaku Ryoho. 2002 Mar;29(3):413-20.
Title:	[Correlation between clinical pathophysiologic factors and expression of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS), and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer].
Author:	Ochiai, Takumi\|Sugitani, Michiharu\|Nishimura, Kazuhiko\|Noguchi, Hajime\|Watanabe, Tomoo\|Sengoku, Hironobu\|Komiyama, Hiromitsu\|Okano, Masao
PMID:	11915731

5.
Journal:	Nihon Geka Gakkai Zasshi. 2002 Aug;103(8):571.
Title:	[Study of cut-off values for orotate phosphoribosyl transferase (OPRT) in colorectal cancer using maximal chi 2 values].
Author:	Ochiai, Takumi\|Sugitani, Michiharu\|Nishimura, Kazuhiko\|Noguchi, Hajime\|Okada, Tsuyoshi\|Suda, Sumito\|Kamiyama, Hirohiko
PMID:	12229160

6.
Journal:	Int J Clin Oncol. 2002 Dec;7(6):335-42.
Title:	Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemosensitivity to 5-FU.
Author:	Isshi, Kimio\|Sakuyama, Toshikazu\|Gen, Tomoyasu\|Nakamura, Yasuyuki\|Kuroda, Toru\|Katuyama, Toshiyuki\|Maekawa, Yoshimi
PMID:	12494248

7.
Journal:	Gan To Kagaku Ryoho. 2002 Dec;29(13):2515-9.
Title:	[Correlation between enzymatic activity and gene expression of orotate phosphoribosyl transferase (OPRT) in colorectal cancer].
Author:	Takumi, Ochiai\|Michiharu, Sugitani\|Kazuhiko, Nishimura\|Hajime, Noguchi\|Tsuyoshi, Okada\|Sumito, Suda\|Hirohiko, Kamiyama\|Nagaoka, Isao
PMID:	12506474

8.
Journal:	Cancer Chemother Pharmacol. 2003 Feb;51(2):155-60.
Title:	Correlation between clinicopathologic factors and kinetics of metabolic enzymes for 5-fluorouracil given to patients with colon carcinoma by two different dosage regimens.
Author:	Katsumata, Kenji\|Tomioka, Hidenori\|Sumi, Tetsuo\|Yamashita, Shinya\|Takagi, Makoto\|Kato, Fumiaki\|Nakamura, Ryuji\|Koyanagi, Yasuhisa\|Aoki, Tatsuya\|Kato, Kohichiro
PMID:	12647017

9.
Journal:	Eur J Cancer. 2003 May;39(7):975-80.
Title:	Chromosomal imbalances associated with acquired resistance to fluoropyrimidines in human colorectal cancer cells.
Author:	Hidaka, S\|Yasutake, T\|Fukushima, M\|Yano, H\|Haseba, M\|Tsuji, T\|Sawai, T\|Yamaguchi, H\|Nakagoe, T\|Ayabe, H\|Tagawa, Y
PMID:	12706367

10.
Journal:	Int J Clin Oncol. 2003 Apr;8(2):72-8.
Title:	Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma.
Author:	Fujii, Ryuta\|Seshimo, Akiyoshi\|Kameoka, Shingo
PMID:	12720098

11.
Journal:	Br J Cancer. 2003 Oct 20;89(8):1486-92.
Title:	Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.
Author:	Ichikawa, W\|Uetake, H\|Shirota, Y\|Yamada, H\|Takahashi, T\|Nihei, Z\|Sugihara, K\|Sasaki, Y\|Hirayama, R
PMID:	14562021

12.
Journal:	Cancer Chemother Pharmacol. 2004 May;53(5):391-6.
Title:	Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis.
Author:	Inokuchi, Mikito\|Uetake, Hiroyuki\|Shirota, Yoshinori\|Yamada, Hiroyuki\|Tajima, Masayuki\|Sugihara, Kenichi
PMID:	15060742

13.
Journal:	Gan To Kagaku Ryoho. 2004 Jul;31(7):1053-6.
Title:	[Choice of chemotherapeutic drugs for colorectal cancers by DPD and OPRT activities in cancer tissues].
Author:	Takemura, Masashi\|Osugi, Harushi\|Lee, Shigeru\|Kaneko, Masahiro\|Tanaka, Yoshinori\|Fujiwara, Yushi\|Nishizawa, Satoshi\|Iwasaki, Hiroshi
PMID:	15272584

14.
Journal:	Clin Cancer Res. 2005 Apr 1;11(7):2612-9.
Title:	Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.
Author:	Kidd, Elizabeth A\|Yu, Jinsheng\|Li, Xia\|Shannon, William D\|Watson, Mark A\|McLeod, Howard L
PMID:	15814641

15.
Journal:	Beijing Da Xue Xue Bao. 2005 Jun 18;37(3):269-72.
Title:	[Expression of metabolic enzymes of fluoropyrimidines in primary colorectal cancer and its clinical significance].
Author:	Wang, Hua\|Dong, Pei-de\|Zhang, Lian-hai\|Ji, Jia-fu
PMID:	15968317

16.
Journal:	Gan To Kagaku Ryoho. 2005 Nov;32(12):1929-34.
Title:	[Expression of mRNA levels of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase of colorectal cancer--relationships among mRNA levels in association with response to 5-FU based treatment].
Author:	Ishida, Hideyuki\|Shirakawa, Kazuo\|Ohsawa, Tomonori\|Sobajima, Jun\|Hayashi, Yoichi\|Nakada, Hiroshi\|Yokoyama, Masaru\|Hashimoto, Daijo
PMID:	16282729

17.
Journal:	Int J Cancer. 2006 Jun 15;118(12):3084-8.
Title:	Prognostic impact of orotate phosphoribosyl transferase among 5-fluorouracil metabolic enzymes in resectable colorectal cancers treated by oral 5-fluorouracil-based adjuvant chemotherapy.
Author:	Ochiai, Takumi\|Nishimura, Kazuhiko\|Noguchi, Hajime\|Kitajima, Masayuki\|Tsukada, Akira\|Watanabe, Emiko\|Nagaoka, Isao\|Futagawa, Shunji
PMID:	16425285

18.
Journal:	Gan To Kagaku Ryoho. 2006 Nov;33(11):1603-9.
Title:	[Prediction of sensitivity to 5-fluorouracil (5-fu) by metabolic and target enzyme activities in colon cancer].
Author:	Yamada, Takeshi\|Tanaka, Noritake\|Yokoi, Kimiyoshi\|Ishikawa, Noriyuki\|Seya, Tomoko\|Horiba, Kouji\|Kanazawa, Yoshikazu\|Shirakawa, Takashi\|Ohkawa, Keiichi\|Kudoh, Hidenori\|Koizumi, Michihiro\|Yoshioka, Masato\|Shinji, Seiichi\|Yamashita, Kiyohiko\|Tajiri, Takashi
PMID:	17108726

19.
Journal:	Oncol Rep. 2006 Dec;16(6):1165-72.
Title:	The expression profiles of orotate phosphoribosyltransferase and dihydropyrimidine dehydrogenase in gastric cancer and their clinical significance.
Author:	Oeda, Mamoru\|Yoshida, Kazuhiro\|Sanada, Yuichi\|Wada, Yoshiyuki\|Suzuki, Takahisa\|Mizuiri, Hirozumi\|Konishi, Kazuo\|Shigematsu, Hideo\|Tanabe, Kazuaki\|Fukushima, Masakazu
PMID:	17089033

20.
Journal:	J Int Med Res. 2006 May-Jun;34(3):307-15.
Title:	Methylenetetrahydrofolate reductase C677T is not associated with expression of pyrimidine metabolic enzyme genes in colorectal cancer.
Author:	Takeda, R\|Kamano, T\|Sakamoto, K\|Sugano, M\|Hosoda, S\|Watanabe, T\|Maeda, T\|Kojima, Y
PMID:	16866026

21.
Journal:	Clin Cancer Res. 2006 Jul 1;12(13):3928-34.
Title:	Orotate phosphoribosyltransferase gene polymorphism predicts toxicity in patients treated with bolus 5-fluorouracil regimen.
Author:	Ichikawa, Wataru\|Takahashi, Takehiro\|Suto, Kenichi\|Sasaki, Yasutsuna\|Hirayama, Renzo
PMID:	16818689

22.
Journal:	J Surg Oncol. 2006 Jul 1;94(1):45-50.
Title:	Prognostic impact of orotate phosphoribosyl transferase activity in resectable colorectal cancers treated by 5-fluorouracil-based adjuvant chemotherapy.
Author:	Ochiai, Takumi\|Nishimura, Kazuhiko\|Noguchi, Hajime\|Kitajima, Masayuki\|Tsuruoka, Yuko\|Takahashi, Yuka\|Tsukada, Akira\|Watanabe, Emiko\|Nagaoka, Isao\|Futagawa, Shunji
PMID:	16788943

23.
Journal:	Gan To Kagaku Ryoho. 2006 Jun;33(6):789-93.
Title:	[Correlation between clinical pathologic factors and enzymatic activity of orotate Phosphoribosyl transferase (OPRT), Dihydropyrimidine dehydrogenase (DPD) and Thymidylate synthase (TS) in colorectal cancer].
Author:	Yamada, Takeshi\|Tanaka, Nobutaka\|Yokoi, Kimiyoshi\|Ishikawa, Noriyuki\|Seya, Tomoko\|Kanazawa, Yoshikazu\|Shirakawa, Takashi\|Ohkawa, Keiichi\|Koizumi, Michihiro\|Ohaki, Yoshiharu\|Yamashita, Kiyohiko\|Tajiri, Takashi
PMID:	16770098

24.
Journal:	Int J Cancer. 2006 Aug 1;119(3):522-6.
Title:	5-fluorouracil-related gene expression levels in primary colorectal cancer and corresponding liver metastasis.
Author:	Kuramochi, Hidekazu\|Hayashi, Kazuhiko\|Uchida, Kazumi\|Miyakura, Satoru\|Shimizu, Daisuke\|Vallbohmer, Daniel\|Park, Seongjin\|Danenberg, Kathleen D\|Takasaki, Ken\|Danenberg, Peter V
PMID:	16572420

25.
Journal:	J Gastroenterol. 2006 Feb;41(2):140-50.
Title:	Influence of chemotherapeutic agents and cytokines on the expression of 5-fluorouracil-associated enzymes in human colon cancer cell lines.
Author:	Miyazaki, Kaori\|Shibahara, Takeshi\|Sato, Daisuke\|Uchida, Kazuhiko\|Suzuki, Hideo\|Matsui, Hirofumi\|Yanaka, Akinori\|Nakahara, Akira\|Matsuzaki, Yasushi
PMID:	16568373

26.
Journal:	Int J Cancer. 2006 Jul 15;119(2):406-13.
Title:	Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response.
Author:	Matsuyama, Ryusei\|Togo, Shinji\|Shimizu, Daisuke\|Momiyama, Nobuyoshi\|Ishikawa, Takashi\|Ichikawa, Yasushi\|Endo, Itaru\|Kunisaki, Chikara\|Suzuki, Harukazu\|Hayasizaki, Yoshihide\|Shimada, Hiroshi
PMID:	16477629

27.
Journal:	Oncol Rep. 2006 Jan;15(1):161-5.
Title:	The relationship between 5-fluorouracil sensitivity and single nucleotide polymorphisms of the orotate phosphoribosyl transferase gene in colorectal cancer.
Author:	Kitajima, Masayuki\|Takita, Naohito\|Hata, Masaki\|Maeda, Tsutomu\|Sakamoto, Kazuhiro\|Kamano, Toshiki\|Ochiai, Takumi
PMID:	16328050

28.
Journal:	Chemotherapy. 2007;53(1):36-41. Epub 2006 Dec 28.
Title:	Upregulation of enzymes metabolizing 5-fluorouracil in colorectal cancer.
Author:	Matsusaka, Satoshi\|Yamasaki, Hajime\|Fukushima, Masakazu\|Wakabayashi, Ichiro
PMID:	17192711

29.
Journal:	Surgery. 2007 Mar;141(3):346-53.
Title:	Clinical role of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine.
Author:	Tokunaga, Yukihiko\|Sasaki, Hirokazu\|Saito, Tohru
PMID:	17349846

30.
Journal:	Scand J Gastroenterol. 2007 Apr;42(4):477-84.
Title:	Modified Irinotecan/5FU/Leucovorin therapy in advanced colorectal cancer and predicting therapeutic efficacy by expression of tumor-related enzymes.
Author:	Yanagisawa, Yoko\|Maruta, Fukuto\|Iinuma, Nobuyoshi\|Ishizone, Satoshi\|Koide, Naohiko\|Nakayama, Jun\|Miyagawa, Shinichi
PMID:	17454858

31.
Journal:	Anticancer Res. 2007 Mar-Apr;27(2):851-6.
Title:	Gene expression profile of 5-fluorouracil metabolic enzymes in primary colorectal cancer: potential as predictive parameters for response to fluorouracil-based chemotherapy.
Author:	Kinoshita, Mizunobu\|Kodera, Yasuhiro\|Hibi, Kenji\|Nakayama, Goro\|Inoue, Tamotsu\|Ohashi, Norifumi\|Ito, Yuichi\|Koike, Masahiko\|Fujiwara, Michitaka\|Nakao, Akimasa
PMID:	17465211

32.
Journal:	Gan To Kagaku Ryoho. 2007 Jul;34(7):1073-7.
Title:	[Expression of mRNA levels of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase and orotate phosphoribosyltransferase in diffusely infiltrating colorectal cancer].
Author:	Ishibashi, Keiichiro\|Sobajima, Jun\|Ohsawa, Tomonori\|Yokoyama, Masaru\|Miyazaki, Tatsuya\|Nakada, Hiroshi\|Gonda, Tsuyoshi\|Ishida, Hideyuki
PMID:	17637543

33.
Journal:	Oncol Rep. 2008 Mar;19(3):729-35.
Title:	Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy.
Author:	Yamada, Hideki\|Iinuma, Hisae\|Watanabe, Toshiaki
PMID:	18288408

34.
Journal:	Int J Mol Med. 2008 Dec;22(6):709-16.
Title:	Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.
Author:	Fukui, Yousuke\|Oka, Toshinori\|Nagayama, Sekio\|Danenberg, Peter V\|Danenberg, Kathleen D\|Fukushima, Masakazu
PMID:	19020767

35.
Journal:	Oncol Rep. 2008 Nov;20(5):1005-11.
Title:	Expression of orotate phosphoribosyltransferase in colorectal carcinoma: an immunohistochemical analysis in several components of neoplastic lesions.
Author:	Sanada, Yuichi\|Yoshida, Kazuhiro\|Hihara, Jun\|Okada, Morihito
PMID:	18949394

36.
Journal:	Anticancer Res. 2008 Jan-Feb;28(1B):389-93.
Title:	5-Fluorouracil-related gene expression in hepatic artery infusion-treated patients with hepatic metastases from colorectal carcinomas.
Author:	Sameshima, Shinichi\|Tomozawa, Shigeru\|Horikoshi, Hiroyuki\|Motegi, Kenta\|Hirayama, Isao\|Koketsu, Shinichiro\|Okada, Toshiyuki\|Kojima, Masaru\|Kon, Youichi\|Sawada, Toshio
PMID:	18383874

37.
Journal:	J Nippon Med Sch. 2008 Feb;75(1):23-7.
Title:	Correlation between clinical pathologic factors and activity of 5-FU-metabolizing enzymes in colorectal cancer.
Author:	Yamada, Takeshi\|Tanaka, Noritake\|Yokoi, Kimiyoshi\|Seya, Tomoko\|Kanazawa, Yoshikazu\|Koizumi, Michihiro\|Ohaki, Yoshiharu\|Tajiri, Takashi
PMID:	18360075

38.
Journal:	BMC Cancer. 2008 Jul 2;8:188.
Title:	Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy.
Author:	Ishikawa, Masashi\|Miyauchi, Takayuki\|Kashiwagi, Yutaka
PMID:	18597678

39.
Journal:	J Clin Pathol. 2009 Apr;62(4):364-9.
Title:	Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancer.
Author:	Kawahara, A\|Akagi, Y\|Hattori, S\|Mizobe, T\|Shirouzu, K\|Ono, M\|Yanagawa, T\|Kuwano, M\|Kage, M
PMID:	19052026

40.
Journal:	Eur J Cancer. 2009 Jul;45(11):1999-2006.
Title:	Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study.
Author:	Koopman, Miriam\|Venderbosch, Sabine\|van Tinteren, Harm\|Ligtenberg, Marjolijn J\|Nagtegaal, Iris\|Van Krieken, Johan H\|Punt, Cornelis J
PMID:	19457654

41.
Journal:	Oncol Rep. 2009 Oct;22(4):901-6.
Title:	Microdissection is essential for gene expression analysis of irradiated rectal cancer tissues.
Author:	Inoue, Yasuhiro\|Tanaka, Koji\|Yokoe, Takeshi\|Saigusa, Susumu\|Toiyama, Yuji\|Miki, Chikao\|Kusunoki, Masato
PMID:	19724871

42.
Journal:	Chemotherapy. 2010;56(2):120-6.
Title:	Correlations of clinicopathological factors with protein expression levels of thymidylate synthase, dihydropyrimidine dehydrogenase and orotate phosphoribosyltransferase in colorectal cancer.
Author:	Sumi, Tetsuo\|Katsumata, Kenji\|Tsuchida, Akihiko\|Ishizaki, Tetsuo\|Shimazu, Motohide\|Aoki, Tatsuya
PMID:	20407238

43.
Journal:	Cancer Sci. 2010 Aug;101(8):1853-60.
Title:	Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV.
Author:	Ito, Yuichi\|Nakanishi, Hayao\|Kodera, Yasuhiro\|Hirai, Takashi\|Nakao, Akimasa\|Kato, Tomoyuki
PMID:	20500514

44.
Journal:	Gan To Kagaku Ryoho. 2010 Jul;37(7):1297-301.
Title:	[Selection of anticancer drug for poorly-differentiated adenocarcinoma of colorectum from the level of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase activities in cancer tissue].
Author:	Takemura, Masashi\|Morimura, Keiichirou\|Yoshida, Kayo\|Osugi, Harushi\|Lee, Shigeru\|Kishida, Satoru
PMID:	20647713

45.
Journal:	Cancer Chemother Pharmacol. 2010 Nov;66(6):1167-71.
Title:	Value of gene polymorphisms as markers of 5-FU therapy response in stage III colon carcinoma: a pilot study.
Author:	Farina-Sarasqueta, Arantza\|van Lijnschoten, Gesina\|Rutten, Harm J T\|van den Brule, Adriaan J C
PMID:	20665215

46.
Journal:	Anticancer Res. 2011 Sep;31(9):2763-71.
Title:	Prognostic significance of thymidylate synthase expression in the adjuvant chemotherapy after resection for pulmonary metastases from colorectal cancer.
Author:	Kaira, Kyoichi\|Okumura, Takehiro\|Ohde, Yasuhisa\|Takahashi, Toshiaki\|Murakami, Haruyasu\|Kondo, Haruhiko\|Nakajima, Takashi\|Yamamoto, Nobuyuki
PMID:	21868518

47.
Journal:	Curr Drug Metab. 2011 Dec;12(10):918-31.
Title:	Pharmacokinetic and metabolism determinants of fluoropyrimidines and oxaliplatin activity in treatment of colorectal patients.
Author:	Gnoni, Antonio\|Russo, Antonio\|Silvestris, Nicola\|Maiello, Evaristo\|Vacca, Angelo\|Marech, Ilaria\|Numico, Gianmauro\|Paradiso, Angelo\|Lorusso, Vito\|Azzariti, Amalia
PMID:	21787270

48.
Journal:	Cancer Invest. 2011 Feb;29(2):130-6.
Title:	Relationship between gene expression of 5-fluorouracil metabolic enzymes and 5-fluorouracil sensitivity in primary cancer cells isolated from malignant ascites.
Author:	Wang, Tingting\|Wang, Lifeng\|Qian, Xiaoping\|Yu, Lixia\|Ding, Yitao\|Liu, Baorui
PMID:	21210725

49.
Journal:	Ann Oncol. 2011 Feb;22(2):355-61.
Title:	Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study.
Author:	Tsunoda, A\|Nakao, K\|Watanabe, M\|Matsui, N\|Ooyama, A\|Kusano, M
PMID:	20647221

50.
Journal:	Gan To Kagaku Ryoho. 2011 Jan;38(1):69-73.
Title:	[Investigation of chemotherapy based on enzyme expression and drug sensitivity test in colorectal cancer].
Author:	Tokunaga, Yukihiko\|Ohnishi, Takanori\|Sasaki, Hirokazu
PMID:	21368461

51.
Journal:	J Surg Oncol. 2012 May;105(6):529-34.
Title:	TS and DPD mRNA levels on formalin-fixed paraffin-embedded specimens as predictors for distant recurrence of rectal cancer treated with preoperative chemoradiotherapy.
Author:	Tanaka, Koji\|Saigusa, Susumu\|Toiyama, Yuji\|Koike, Yuki\|Okugawa, Yoshinaga\|Yokoe, Takeshi\|Inoue, Yasuhiro\|Kobayashi, Minako\|Miki, Chikao\|Kusunoki, Masato
PMID:	22006578

52.
Journal:	Anticancer Res. 2012 Jun;32(6):2277-82.
Title:	Expression of dihydropyrimidine dehydrogenase, orotate phosphoribosyl transferase and thymidylate synthase in patients with primary colorectal cancer, and associations with site of first metastasis.
Author:	Akagi, Yoshito\|Kinugasa, Tetsushi\|Mizobe, Tomoaki\|Kawahara, Akihiko\|Kage, Masayoshi\|Shirouzu, Kazuo
PMID:	22641663

53.
Journal:	Oncol Lett. 2012 May;3(5):983-989.
Title:	Thymidylate synthase and thymidine phosphorylase mRNA expression in primary lesions using laser capture microdissection is useful for prediction of the efficacy of FOLFOX treatment in colorectal cancer patients with liver metastasis.
Author:	Kumamoto, Kensuke\|Kuwabara, Koki\|Tajima, Yusuke\|Amano, Kunihiko\|Hatano, Satoshi\|Ohsawa, Tomonori\|Okada, Norimichi\|Ishibashi, Keiichiro\|Haga, Norihiro\|Ishida, Hideyuki
PMID:	22783377

54.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2012 Aug;32(8):1179-81.
Title:	[Expressions of orotate phosphoribosyltransferase in colorectal carcinoma and its correlations with toxicities of chemotherapy].
Author:	Dong, Qiumei\|Huang, Saihua\|Li, Ying\|Liu, Jianhua
PMID:	22931617

55.
Journal:	Hepatogastroenterology. 2013 Mar-Apr;60(122):291-5.
Title:	Analysis of the mRNA expression levels of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD) and orotate phosphoribosyl transferase (OPRT) in liver metastases from colorectal cancer.
Author:	Yamane, Takao\|Seshimo, Akiyoshi\|Kameoka, Shingo
PMID:	22945388

56.
Journal:	Mol Clin Oncol. 2013 May;1(3):453-460.
Title:	Predictive value of orotate phosphoribosyltransferase in colorectal cancer patients receiving 5-FU-based chemotherapy.
Author:	Komori, Shuji\|Osada, Shinji\|Tomita, Hiroyuki\|Nishio, Kimitoshi\|Kumazawa, Iwao\|Tachibana, Susumu\|Tsuchiya, Juji\|Yoshida, Kazuhiro
PMID:	24649191

57.
Journal:	Oncol Rep. 2013 Feb;29(2):437-44.
Title:	Factors predicting the response to oral fluoropyrimidine drugs: a phase II trial on the individualization of postoperative adjuvant chemotherapy using oral fluorinated pyrimidines in stage III colorectal cancer treated by curative resection (ACT-01 Study)
Author:	Mori, Takeo\|Ohue, Masayuki\|Takii, Yasumasa\|Hashizume, Tadashi\|Kato, Tomoyuki\|Kotake, Kenjiro\|Sato, Toshihiko\|Tango, Toshiro
PMID:	23232805

58.
Journal:	Pharmacogenomics J. 2013 Apr;13(2):148-58.
Title:	Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.
Author:	Griffith, M\|Mwenifumbo, J C\|Cheung, P Y\|Paul, J E\|Pugh, T J\|Tang, M J\|Chittaranjan, S\|Morin, R D\|Asano, J K\|Ally, A A\|Miao, L\|Lee, A\|Chan, S Y\|Taylor, G\|Severson, T\|Hou, Y-C\|Griffith, O L\|Cheng, G S W\|Novik, K\|Moore, R\|Luk, M\|Owen, D\|Brown, C J\|Morin, G B
PMID:	22249354

59.
Journal:	Mol Med Rep. 2014 Feb;9(2):669-76.
Title:	Cinnamaldehyde/chemotherapeutic agents interaction and drug-metabolizing genes in colorectal cancer.
Author:	Yu, Chen\|Liu, Shen-Lin\|Qi, Ming-Hao\|Zou, Xi
PMID:	24276478

60.
Journal:	Oncol Rep. 2014 Sep;32(3):887-92.
Title:	Impact of 5-fluorouracil metabolizing enzymes on chemotherapy in patients with resectable colorectal cancer.
Author:	Ochiai, Takumi\|Umeki, Masahiko\|Miyake, Hiroshi\|Iida, Tatsumi\|Okumura, Minoru\|Ohno, Kazuhide\|Sakamoto, Masashi\|Miyoshi, Nobukazu\|Takahashi, Masahiko\|Tsumura, Hidenori\|Tokunaga, Yukihiko\|Naitou, Haruhiko\|Fukui, Takuji
PMID:	24994673

61.
Journal:	BMC Cancer. 2016 Oct 12;16(1):795.
Title:	Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma.
Author:	Kunicka, T\|Prochazka, P\|Krus, I\|Bendova, P\|Protivova, M\|Susova, S\|Hlavac, V\|Liska, V\|Novak, P\|Schneiderova, M\|Pitule, P\|Bruha, J\|Vycital, O\|Vodicka, P\|Soucek, P
PMID:	27733154

62.
Journal:	Radiat Oncol. 2017 Mar 27;12(1):62.
Title:	A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.
Author:	Kim, Sun Young\|Baek, Ji Yeon\|Oh, Jae Hwan\|Park, Sung Chan\|Sohn, Dae Kyung\|Kim, Min Ju\|Chang, Hee Jin\|Kong, Sun-Young\|Kim, Dae Yong
PMID:	28347333

63.
Journal:	Pharmacol Res. 2017 Jun;120:133-137.
Title:	Identification of new SNPs associated with severe toxicity to capecitabine.
Author:	Pellicer, Marta\|Garcia-Gonzalez, Xandra\|Garcia, Maria I\|Robles, Luis\|Gravalos, Cristina\|Garcia-Alfonso, Pilar\|Pachon, Vanessa\|Longo, Federico\|Martinez, Virginia\|Blanco, Carolina\|Iglesias, Irene\|Sanjurjo, Maria\|Lopez-Fernandez, Luis A
PMID:	28347776

64.
Journal:	Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7697-E7706.
Title:	Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC.
Author:	Satoh, Kiyotoshi\|Yachida, Shinichi\|Sugimoto, Masahiro\|Oshima, Minoru\|Nakagawa, Toshitaka\|Akamoto, Shintaro\|Tabata, Sho\|Saitoh, Kaori\|Kato, Keiko\|Sato, Saya\|Igarashi, Kaori\|Aizawa, Yumi\|Kajino-Sakamoto, Rie\|Kojima, Yasushi\|Fujishita, Teruaki\|Enomoto, Ayame
PMID:	28847964