Primary Site >> Colorectal Cancer

Gene >> UHMK1

Journal: Adv Exp Med Biol. 1983;163:341-57.
Title: Effects of 5,8-dideazaisopteroylglutamate and its possible tri-gamma-glutamyl metabolite (5,8-dideazaisoPteGlu3) on colon adenocarcinoma, and the folate dependent enzymes thymidylate synthase and dihydrofolate reductase.
Author: Fernandes, D J|Cardenas, R M|Bertino, J R|Hynes, J B
PMID: 6688493
Journal: Int J Cancer. 1996 Jan 17;65(2):173-7.
Title: Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase-mediated dUTP-biotin nick end labeling.
Author: Tatebe, S|Ishida, M|Kasagi, N|Tsujitani, S|Kaibara, N|Ito, H
PMID: 8567113
Journal: Clin Cancer Res. 1999 Mar;5(3):643-54.
Title: Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
Author: van Triest, B|Pinedo, H M|van Hensbergen, Y|Smid, K|Telleman, F|Schoenmakers, P S|van der Wilt, C L|van Laar, J A|Noordhuis, P|Jansen, G|Peters, G J
PMID: 10100718
Journal: Expert Opin Pharmacother. 2013 Nov;14(16):2203-20.
Title: Protein kinase inhibitors in metastatic colorectal cancer. Let's pick patients, tumors, and kinase inhibitors to piece the puzzle together!
Author: Stintzing, Sebastian|Lenz, Heinz-Josef
PMID: 23941461
Journal: Eur J Med Chem. 2017 Oct 20;139:250-262.
Title: Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.
Author: Eldehna, Wagdy M|Abo-Ashour, Mahmoud F|Nocentini, Alessio|Gratteri, Paola|Eissa, Ibrahim H|Fares, Mohamed|Ismael, Omnia E|Ghabbour, Hazem A|Elaasser, Mahmoud M|Abdel-Aziz, Hatem A|Supuran, Claudiu T
PMID: 28802125
Journal: Bioorg Chem. 2018 Sep 7;81:425-432.
Title: Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.
Author: Eldehna, Wagdy M|Nocentini, Alessio|Al-Rashood, Sara T|Hassan, Ghada S|Alkahtani, Hamad M|Almehizia, Abdulrahman A|Reda, Ahmed M|Abdel-Aziz, Hatem A|Supuran, Claudiu T
PMID: 30219719