Primary Site >> Colorectal Cancer

Gene >> UBXN2A

Journal: Cell Death Dis. 2014 Mar 13;5:e1118.
Title: Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells.
Author: Sane, S|Abdullah, A|Boudreau, D A|Autenried, R K|Gupta, B K|Wang, X|Wang, H|Schlenker, E H|Zhang, D|Telleria, C|Huang, L|Chauhan, S C|Rezvani, K
PMID: 24625977
Journal: Oncotarget. 2015 Sep 15;6(27):23561-81.
Title: A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2.
Author: Abdullah, Ammara|Sane, Sanam|Branick, Kate A|Freeling, Jessica L|Wang, Hongmin|Zhang, Dong|Rezvani, Khosrow
PMID: 26188124
Journal: J Cancer. 2015 Sep 3;6(11):1066-78.
Title: Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells.
Author: Abdullah, Ammara|Sane, Sanam|Freeling, Jessica L|Wang, Hongmin|Zhang, Dong|Rezvani, Khosrow
PMID: 26516353
Journal: Cell Stress Chaperones. 2016 Mar;21(2):313-26.
Title: Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.
Author: Sane, Sanam|Abdullah, Ammara|Nelson, Morgan E|Wang, Hongmin|Chauhan, Subhash C|Newton, Samuel S|Rezvani, Khosrow
PMID: 26634371
Journal: Mol Oncol. 2018 Oct;12(10):1753-1777.
Title: UBXN2A enhances CHIP-mediated proteasomal degradation of oncoprotein mortalin-2 in cancer cells.
Author: Sane, Sanam|Hafner, Andre|Srinivasan, Rekha|Masood, Daniall|Slunecka, John L|Noldner, Collin J|Hanson, Alex D|Kruisselbrink, Taylor|Wang, Xuejun|Wang, Yiyang|Yin, Jun|Rezvani, Khosrow
PMID: 30107089