Primary Site >> Colorectal Cancer
Gene >> TPBG
| 1. | |||||||||||
| Journal: | Br J Cancer. 1994 May;69(5):899-902. | ||||||||||
| Title: | Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma. | ||||||||||
| Author: | Starzynska, T|Marsh, P J|Schofield, P F|Roberts, S A|Myers, K A|Stern, P L | ||||||||||
| PMID: | 8180020 | ||||||||||
| 2. | |||||||||||
| Journal: | J Cell Sci. 1995 Aug;108 ( Pt 8):2905-16. | ||||||||||
| Title: | Metastasis-associated 5T4 oncofoetal antigen is concentrated at microvillus projections of the plasma membrane. | ||||||||||
| Author: | Carsberg, C J|Myers, K A|Evans, G S|Allen, T D|Stern, P L | ||||||||||
| PMID: | 7593330 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Gynecol Cancer. 1995 Jul;5(4):269-274. | ||||||||||
| Title: | 5T4 oncofetal antigen expression in ovarian carcinoma. | ||||||||||
| Author: | Wrigley, E.|McGown, A.T.|Rennison, J.|Swindell, R.|Crowther, D.|Starzynska, T.|Stern, P.L. | ||||||||||
| PMID: | 11578488 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 1997 Nov;3(11):1923-30. | ||||||||||
| Title: | Low intercellular adhesion molecule 1 and high 5T4 expression on tumor cells correlate with reduced disease-free survival in colorectal carcinoma patients. | ||||||||||
| Author: | Mulder, W M|Stern, P L|Stukart, M J|de Windt, E|Butzelaar, R M|Meijer, S|Ader, H J|Claessen, A M|Vermorken, J B|Meijer, C J|Wagstaff, J|Scheper, R J|Bloemena, E | ||||||||||
| PMID: | 9815581 | ||||||||||
| 5. | |||||||||||
| Journal: | Oral Oncol. 2001 Jan;37(1):57-64. | ||||||||||
| Title: | The pattern of expression of the 5T4 oncofoetal antigen on normal, dysplastic and malignant oral mucosa. | ||||||||||
| Author: | Ali, A|Langdon, J|Stern, P|Partridge, M | ||||||||||
| PMID: | 11120484 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Sep 15;11(18):6550-7. | ||||||||||
| Title: | Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. | ||||||||||
| Author: | Roessler, Markus|Rollinger, Wolfgang|Palme, Stefan|Hagmann, Marie-Luise|Berndt, Peter|Engel, Alfred M|Schneidinger, Bernd|Pfeffer, Michael|Andres, Herbert|Karl, Johann|Bodenmuller, Heinz|Ruschoff, Josef|Henkel, Thomas|Rohr, Gerhard|Rossol, Siegbert|Rosch, | ||||||||||
| PMID: | 16166432 | ||||||||||
| 7. | |||||||||||
| Journal: | Immunology. 2006 May;118(1):50-7. | ||||||||||
| Title: | Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4. | ||||||||||
| Author: | Redchenko, Irina|Harrop, Richard|Ryan, Matthew G|Hawkins, Robert E|Carroll, Miles W | ||||||||||
| PMID: | 16630022 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3416-24. | ||||||||||
| Title: | Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial. | ||||||||||
| Author: | Harrop, Richard|Connolly, Noel|Redchenko, Irina|Valle, Juan|Saunders, Mark|Ryan, Matthew G|Myers, Kevin A|Drury, Noel|Kingsman, Susan M|Hawkins, Robert E|Carroll, Miles W | ||||||||||
| PMID: | 16740766 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2006 Dec 27;1:e129. | ||||||||||
| Title: | CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. | ||||||||||
| Author: | Clarke, Sarah L|Betts, Gareth J|Plant, Andrea|Wright, Kate L|El-Shanawany, Tariq M|Harrop, Richard|Torkington, Jared|Rees, Brian I|Williams, Geraint T|Gallimore, Awen M|Godkin, Andrew J | ||||||||||
| PMID: | 17205133 | ||||||||||
| 10. | |||||||||||
| Journal: | Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4487-94. | ||||||||||
| Title: | Vaccination of colorectal cancer patients with modified vaccinia ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses. | ||||||||||
| Author: | Harrop, Richard|Drury, Noel|Shingler, William|Chikoti, Priscilla|Redchenko, Irina|Carroll, Miles W|Kingsman, Susan M|Naylor, Stuart|Melcher, Alan|Nicholls, Joanna|Wassan, Harpreet|Habib, Nagy|Anthoney, Alan | ||||||||||
| PMID: | 17671134 | ||||||||||
| 11. | |||||||||||
| Journal: | J Immunother. 2008 Nov-Dec;31(9):820-9. | ||||||||||
| Title: | An MVA-based vaccine targeting the oncofetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases. | ||||||||||
| Author: | Elkord, Eyad|Dangoor, Adam|Drury, Noel L|Harrop, Richard|Burt, Deborah J|Drijfhout, Jan W|Hamer, Caroline|Andrews, Danielle|Naylor, Stuart|Sherlock, David|Hawkins, Robert E|Stern, Peter L | ||||||||||
| PMID: | 18833005 | ||||||||||
| 12. | |||||||||||
| Journal: | Expert Opin Biol Ther. 2008 Dec;8(12):1947-53. | ||||||||||
| Title: | Development of modified vaccinia Ankara-5T4 as specific immunotherapy for advanced human cancer. | ||||||||||
| Author: | Tykodi, Scott S|Thompson, John A | ||||||||||
| PMID: | 18990081 | ||||||||||
| 13. | |||||||||||
| Journal: | Int Immunol. 2008 Aug;20(8):1057-66. | ||||||||||
| Title: | Identification and functional validation of MHC class I epitopes in the tumor-associated antigen 5T4. | ||||||||||
| Author: | Shingler, William H|Chikoti, Priscilla|Kingsman, Susan M|Harrop, Richard | ||||||||||
| PMID: | 18567615 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2008 Jul;57(7):977-86. | ||||||||||
| Title: | Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses. | ||||||||||
| Author: | Harrop, Richard|Drury, Noel|Shingler, William|Chikoti, Priscilla|Redchenko, Irina|Carroll, Miles W|Kingsman, Susan M|Naylor, Stuart|Griffiths, Richard|Steven, Neil|Hawkins, Robert E | ||||||||||
| PMID: | 18060404 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2009 Oct;58(10):1657-67. | ||||||||||
| Title: | Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4). | ||||||||||
| Author: | Elkord, Eyad|Dangoor, Adam|Burt, Deborah J|Southgate, Thomas D|Daayana, Sai|Harrop, Richard|Drijfhout, Jan W|Sherlock, David|Hawkins, Robert E|Stern, Peter L | ||||||||||
| PMID: | 19221742 | ||||||||||
| 16. | |||||||||||
| Journal: | J Immunother. 2010 Nov-Dec;33(9):999-1005. | ||||||||||
| Title: | Cross-trial analysis of immunologic and clinical data resulting from phase I and II trials of MVA-5T4 (TroVax) in colorectal, renal, and prostate cancer patients. | ||||||||||
| Author: | Harrop, Richard|Shingler, William|Kelleher, Michelle|de Belin, Jackie|Treasure, Peter | ||||||||||
| PMID: | 20948436 | ||||||||||
| 17. | |||||||||||
| Journal: | Hum Vaccin. 2010 Oct;6(10):784-91. Epub 2010 Oct 1. | ||||||||||
| Title: | TroVax, a recombinant modified vaccinia Ankara virus encoding 5T4: lessons learned and future development. | ||||||||||
| Author: | Kim, Dae Won|Krishnamurthy, Vikram|Bines, Steven D|Kaufman, Howard L | ||||||||||
| PMID: | 20975327 | ||||||||||
| 18. | |||||||||||
| Journal: | Gut. 2012 Aug;61(8):1163-71. | ||||||||||
| Title: | Suppression of tumour-specific CD4(+) T cells by regulatory T cells is associated with progression of human colorectal cancer. | ||||||||||
| Author: | Betts, Gareth|Jones, Emma|Junaid, Syed|El-Shanawany, Tariq|Scurr, Martin|Mizen, Paul|Kumar, Mayur|Jones, Sion|Rees, Brian|Williams, Geraint|Gallimore, Awen|Godkin, Andrew | ||||||||||
| PMID: | 22207629 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Immunol Res. 2013 Dec;1(6). | ||||||||||
| Title: | Escalating regulation of 5T4-specific IFN-gamma(+) CD4(+) T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy. | ||||||||||
| Author: | Scurr, Martin|Bloom, Anja|Pembroke, Tom|Srinivasan, Rohit|Brown, Clare|Smart, Kathryn|Bridgeman, Hayley|Davies, Mike|Hargest, Rachel|Phillips, Simon|Christian, Adam|Hockey, Tom|Gallimore, Awen|Godkin, Andrew | ||||||||||
| PMID: | 24409450 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2014 Apr 15;9(4):e95200. | ||||||||||
| Title: | Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen. | ||||||||||
| Author: | Patterson, Kelcey G|Dixon Pittaro, Jennifer L|Bastedo, Peter S|Hess, David A|Haeryfar, S M Mansour|McCormick, John K | ||||||||||
| PMID: | 24736661 | ||||||||||
| 21. | |||||||||||
| Journal: | Hum Vaccin Immunother. 2014;10(11):3196-200. | ||||||||||
| Title: | TroVax in colorectal cancer. | ||||||||||
| Author: | Rowe, Julie|Cen, Putao | ||||||||||
| PMID: | 25483641 | ||||||||||
| 22. | |||||||||||
| Journal: | J Natl Cancer Inst. 2015 Feb 9;107(4). pii: djv001. | ||||||||||
| Title: | Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer. | ||||||||||
| Author: | Scurr, Martin J|Brown, Clare M|Costa Bento, Diana F|Betts, Gareth J|Rees, Brian I|Hills, Robert K|Gallimore, Awen|Godkin, Andrew | ||||||||||
| PMID: | 25669203 | ||||||||||
| 23. | |||||||||||
| Journal: | JAMA Oncol. 2017 Oct 12;3(10):e172579. | ||||||||||
| Title: | Effect of Modified Vaccinia Ankara-5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial. | ||||||||||
| Author: | Scurr, Martin|Pembroke, Tom|Bloom, Anja|Roberts, David|Thomson, Amanda|Smart, Kathryn|Bridgeman, Hayley|Adams, Richard|Brewster, Alison|Jones, Robert|Gwynne, Sarah|Blount, Daniel|Harrop, Richard|Wright, Melissa|Hills, Robert|Gallimore, Awen|Godkin, Andrew | ||||||||||
| PMID: | 28880972 | ||||||||||
| 24. | |||||||||||
| Journal: | Am J Cancer Res. 2018 Apr 1;8(4):610-623. eCollection 2018. | ||||||||||
| Title: | A novel 5T4-targeting antibody-drug conjugate H6-DM4 exhibits potent therapeutic efficacy in gastrointestinal tumor xenograft models. | ||||||||||
| Author: | Wang, Ruixue|Lai, Qinhuai|Tang, Liangze|Tao, Yiran|Yao, Yuqin|Liu, Yu|Lu, Ying|Shen, Chaoyong|Lu, Ran|Fan, Chuanwen|Zhang, Ruirui|Wang, Yuxi|Yu, Lin|Yang, Tinghan|Wu, Yangping|Peng, Yujia|Wei, Xian|Fu, Yuyin|Lai, Weirong|Gou, Lantu|Yang, Jinliang | ||||||||||
| PMID: | 29736307 | ||||||||||