Primary Site >> Pancreatic Cancer

Gene >> TLR7

Journal: J Clin Invest. 2012 Nov;122(11):4118-29.
Title: Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.
Author: Ochi, Atsuo|Graffeo, Christopher S|Zambirinis, Constantinos P|Rehman, Adeel|Hackman, Michael|Fallon, Nina|Barilla, Rocky M|Henning, Justin R|Jamal, Mohsin|Rao, Raghavendra|Greco, Stephanie|Deutsch, Michael|Medina-Zea, Marco V|Bin Saeed, Usama|Ego-Osuala,
PMID: 23023703
Journal: JAKSTAT. 2013 Jan 1;2(1):e23011.
Title: TLR7 inhibition: A novel strategy for pancreatic cancer treatment?
Author: Eigenbrod, Tatjana|Dalpke, Alexander H
PMID: 24058792
Journal: World J Gastroenterol. 2014 May 21;20(19):5808-17.
Title: Intervention on toll-like receptors in pancreatic cancer.
Author: Vaz, Juan|Andersson, Roland
PMID: 24914341
Journal: Oncotarget. 2015 Mar 10;6(7):4663-76.
Title: Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors.
Author: Scholch, Sebastian|Rauber, Conrad|Tietz, Alexandra|Rahbari, Nuh N|Bork, Ulrich|Schmidt, Thomas|Kahlert, Christoph|Haberkorn, Uwe|Tomai, Mark A|Lipson, Kenneth E|Carretero, Rafael|Weitz, Jurgen|Koch, Moritz|Huber, Peter E
PMID: 25609199
Journal: Int J Oncol. 2015 Sep;47(3):857-66.
Title: TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer.
Author: Grimmig, Tanja|Matthes, Niels|Hoeland, Katharina|Tripathi, Sudipta|Chandraker, Anil|Grimm, Martin|Moench, Romana|Moll, Eva-Maria|Friess, Helmut|Tsaur, Igor|Blaheta, Roman A|Germer, Cristoph T|Waaga-Gasser, Ana Maria|Gasser, Martin
PMID: 26134824
Journal: Mol Med Rep. 2015 Oct;12(4):6079-85.
Title: Activation of Toll-like receptor 7 inhibits the proliferation and migration, and induces the apoptosis of pancreatic cancer cells.
Author: Zou, Bing-Bing|Wang, Fang|Li, Lei|Cheng, Feng-Wei|Jin, Rui|Luo, Xin|Zhu, Li-Xin|Geng, Xiaoping|Zhang, Sheng-Quan
PMID: 26238718
Journal: Mol Med Rep. 2016 Feb;13(2):1807-12.
Title: Activation of Toll-like receptor 7 regulates the expression of IFN-lambda1, p53, PTEN, VEGF, TIMP-1 and MMP-9 in pancreatic cancer cells.
Author: Wang, Fang|Jin, Rui|Zou, Bing-Bing|Li, Lei|Cheng, Feng-Wei|Luo, Xin|Geng, Xiaoping|Zhang, Sheng-Quan
PMID: 26718740
Journal: Cancer Res. 2018 Sep 12. pii: 0008-5472.CAN-17-3878.
Title: The TLR7/8/9 antagonist IMO-8503 inhibits cancer-induced cachexia.
Author: Calore, Federica|Londhe, Priya|Fadda, Paolo|Nigita, Giovanni|Casadei, Lucia|Marceca, Gioacchino Paolo|Fassan, Matteo|Lovat, Francesca|Gasparini, Pierluigi|Rizzotto, Lara|Zanesi, Nicola|Jackson, Devine|Mehta, Svasti|Nana-Sinkam, Patrick|Sampath, Deepa|Poll
PMID: 30209066