Primary Site >> Pancreatic Cancer

Gene >> THBS1

Journal: J Surg Res. 1998 Apr;76(1):86-90.
Title: The effect of thrombospondin-1 and TGF-beta 1 on pancreatic cancer cell invasion.
Author: Albo, D|Berger, D H|Tuszynski, G P
PMID: 9695745
Journal: J Gastrointest Surg. 1999 Jul-Aug;3(4):411-7.
Title: Thrombospondin-1 and transforming growth factor beta-1 upregulate plasminogen activator inhibitor type 1 in pancreatic cancer.
Author: Albo, D|Berger, D H|Vogel, J|Tuszynski, G P
PMID: 10482694
Journal: Cancer Res. 2000 Apr 1;60(7):1835-9.
Title: Hypermethylation of multiple genes in pancreatic adenocarcinoma.
Author: Ueki, T|Toyota, M|Sohn, T|Yeo, C J|Issa, J P|Hruban, R H|Goggins, M
PMID: 10766168
Journal: Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9624-9.
Title: Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis.
Author: Schwarte-Waldhoff, I|Volpert, O V|Bouck, N P|Sipos, B|Hahn, S A|Klein-Scory, S|Luttges, J|Kloppel, G|Graeven, U|Eilert-Micus, C|Hintelmann, A|Schmiegel, W
PMID: 10944227
Journal: Virchows Arch. 2001 Feb;438(2):116-20.
Title: Expression of thrombospondin-1 in pancreatic carcinoma: correlation with microvessel density.
Author: Kasper, H U|Ebert, M|Malfertheiner, P|Roessner, A|Kirkpatrick, C J|Wolf, H K
PMID: 11253112
Journal: Histol Histopathol. 2001 Apr;16(2):345-51.
Title: The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer.
Author: Wakiyama, T|Shinohara, T|Shirakusa, T|John, A S|Tuszynski, G P
PMID: 11332689
Journal: Pathol Oncol Res. 2001;7(4):251-9.
Title: Expression of thrombospondin-1 in human pancreatic adenocarcinomas: role in matrix metalloproteinase-9 production.
Author: Qian, X|Rothman, V L|Nicosia, R F|Tuszynski, G P
PMID: 11882904
Journal: Int J Oncol. 2002 Dec;21(6):1189-95.
Title: Thrombospondin-1 expression as a prognostic predictor of pancreatic ductal carcinoma.
Author: Tobita, Kosuke|Kijima, Hiroshi|Dowaki, Shoichi|Oida, Yasuhisa|Kashiwagi, Hiroyuki|Ishii, Masanori|Sugio, Yoshinori|Sekka, Takafumi|Ohtani, Yasuo|Tanaka, Makiko|Inokuchi, Sadaki|Makuuchi, Hiroyasu
PMID: 12429967
Journal: Angiogenesis. 2002;5(3):181-90.
Title: Pancreatic tumor growth is regulated by the balance between positive and negative modulators of angiogenesis.
Author: Schuch, Gunter|Kisker, Oliver|Atala, Anthony|Soker, Shay
PMID: 12831059
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5622-30.
Title: Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model.
Author: Zhang, Xuefeng|Galardi, Eric|Duquette, Mark|Lawler, Jack|Parangi, Sareh
PMID: 16061881
Journal: Mol Cancer Res. 2005 Jul;3(7):413-23.
Title: Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justification for K-ras-directed therapy.
Author: Fleming, Jason B|Shen, Guo-Liang|Holloway, Shane E|Davis, Mishel|Brekken, Rolf A
PMID: 16046552
Journal: Clin Cancer Res. 2005 Mar 15;11(6):2337-44.
Title: Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.
Author: Zhang, Xuefeng|Galardi, Eric|Duquette, Mark|Delic, Marko|Lawler, Jack|Parangi, Sareh
PMID: 15788685
Journal: Cancer Lett. 2007 Mar 8;247(1):143-9.
Title: Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model.
Author: Zhang, Xuefeng|Connolly, Caitlin|Duquette, Mark|Lawler, Jack|Parangi, Sareh
PMID: 16757110
Journal: Clin Cancer Res. 2007 Jul 1;13(13):3968-76.
Title: Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin.
Author: Zhang, Xuefeng|Xu, Jianfeng|Lawler, Jack|Terwilliger, Ernest|Parangi, Sareh
PMID: 17606731
Journal: Zhonghua Wai Ke Za Zhi. 2007 Sep 1;45(17):1199-201.
Title: [Relationship between changes of serum concentrations of antiangiogenic factors and disease progression in patients of pancreatic carcinoma].
Author: Dai, Meng-hua|Yan, Chang-qing|Zhao, Yu-pei|Song, Yi-min
PMID: 18067717
Journal: Mol Cancer Ther. 2008 Mar;7(3):638-47.
Title: Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model.
Author: Laquente, Berta|Lacasa, Cristina|Ginesta, Mireia M|Casanovas, Oriol|Figueras, Agnes|Galan, Maica|Ribas, Ignacio Garcia|Germa, Josep Ramon|Capella, Gabriel|Vinals, Francesc
PMID: 18347150
Journal: Mol Med Rep. 2008 May-Jun;1(3):423-7.
Title: Thrombospondin-2 inhibits tumor cell invasion through the modulation of MMP-9 and uPA in pancreatic cancer cells.
Author: Nakamura, Masato|Oida, Yasuhisa|Abe, Yoshyuki|Yamazaki, Hitoshi|Mukai, Masaya|Matsuyama, Masahiro|Chijiwa, Tsuyoshi|Matsumoto, Hozumi|Ueyama, Yoshito
PMID: 21479427
Journal: J Surg Oncol. 2009 Feb 1;99(2):119-22.
Title: Methylation profile of circulating plasma DNA in patients with pancreatic cancer.
Author: Melnikov, Anatoliy A|Scholtens, Denise|Talamonti, Mark S|Bentrem, David J|Levenson, Victor V
PMID: 19065635
Journal: Mol Cancer Ther. 2009 Jul;8(7):1779-86.
Title: Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis.
Author: McElroy, Michele K|Kaushal, Sharmeela|Tran Cao, Hop S|Moossa, A R|Talamini, Mark A|Hoffman, Robert M|Bouvet, Michael
PMID: 19584238
Journal: Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17769-74.
Title: Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer.
Author: Laklai, Hanane|Laval, Severine|Dumartin, Laurent|Rochaix, Philippe|Hagedorn, Martin|Bikfalvi, Andreas|Le Guellec, Sophie|Delisle, Marie-Bernadette|Schally, Andrew V|Susini, Christiane|Pyronnet, Stephane|Bousquet, Corinne
PMID: 19805200
Journal: Gastroenterology. 2010 Apr;138(4):1595-606, 1606.e1-8.
Title: Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells.
Author: Dumartin, Laurent|Quemener, Cathy|Laklai, Hanane|Herbert, John|Bicknell, Roy|Bousquet, Corinne|Pyronnet, Stephane|Castronovo, Vincent|Schilling, Martin K|Bikfalvi, Andreas|Hagedorn, Martin
PMID: 20080097
Journal: Genes Cancer. 2010 Jun;1(6):597-604.
Title: MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms.
Author: Felsher, Dean W
PMID: 21037952
Journal: Gene Ther. 2010 Sep;17(9):1085-97.
Title: A combinatorial approach for targeted delivery using small molecules and reversible masking to bypass nonspecific uptake in vivo.
Author: Shi, Q|Nguyen, A T|Angell, Y|Deng, D|Na, C-R|Burgess, K|Roberts, D D|Brunicardi, F C|Templeton, N S
PMID: 20463761
Journal: Neoplasia. 2011 Mar;13(3):217-29.
Title: Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo.
Author: Canu, Bastianina|Fioravanti, Anna|Orlandi, Paola|Di Desidero, Teresa|Ali, Greta|Fontanini, Gabriella|Di Paolo, Antonello|Del Tacca, Mario|Danesi, Romano|Bocci, Guido
PMID: 21390185
Journal: Neoplasia. 2011 May;13(5):419-27.
Title: Myelosuppression of thrombocytes and monocytes is associated with a lack of synergy between chemotherapy and anti-VEGF treatment.
Author: Starlinger, Patrick|Brugger, Philipp|Schauer, Dominic|Sommerfeldt, Silvia|Tamandl, Dietmar|Kuehrer, Irene|Schoppmann, Sebastian F|Gnant, Michael|Brostjan, Christine
PMID: 21532882
Journal: Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9939-44.
Title: Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner.
Author: Xie, Liang|Duncan, Michael B|Pahler, Jessica|Sugimoto, Hikaru|Martino, Margot|Lively, Julie|Mundel, Thomas|Soubasakos, Mary|Rubin, Kristofer|Takeda, Takaaki|Inoue, Masahiro|Lawler, Jack|Hynes, Richard O|Hanahan, Douglas|Kalluri, Raghu
PMID: 21622854
Journal: Dis Markers. 2011;31(2):55-65.
Title: Platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts.
Author: Starlinger, Patrick|Alidzanovic, Lejla|Schauer, Dominic|Brugger, Philipp|Sommerfeldt, Silvia|Kuehrer, Irene|Schoppmann, Sebastian F|Gnant, Michael|Brostjan, Christine
PMID: 21896999
Journal: Asian Pac J Cancer Prev. 2012;13(3):753-9.
Title: Knockdown of radixin by RNA interference suppresses the growth of human pancreatic cancer cells in vitro and in vivo.
Author: Chen, Shu-Dong|Song, Mao-Min|Zhong, Zhi-Qiang|Li, Na|Wang, Pi-Lin|Cheng, Shi|Bai, Ri-Xing|Yuan, Hui-Sheng
PMID: 22631643
Journal: Neoplasia. 2012 Sep;14(9):833-45.
Title: Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1.
Author: Bocci, Guido|Fioravanti, Anna|Orlandi, Paola|Di Desidero, Teresa|Natale, Gianfranco|Fanelli, Giovanni|Viacava, Paolo|Naccarato, Antonio Giuseppe|Francia, Giulio|Danesi, Romano
PMID: 23019415
Journal: Biomed Environ Sci. 2012 Aug;25(4):465-70.
Title: S100A4 siRNA inhibits human pancreatic cancer cell invasion in vitro.
Author: Li, Na|Song, Mao Min|Chen, Xiao Hua|Liu, Li Hui|Li, Feng Sheng
PMID: 23026527
Journal: Int J Cancer. 2013 Nov 15;133(10):2464-72.
Title: Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells.
Author: Vives, Marta|Ginesta, Mireia M|Gracova, Kristina|Graupera, Mariona|Casanovas, Oriol|Capella, Gabriel|Serrano, Teresa|Laquente, Berta|Vinals, Francesc
PMID: 23649709
Journal: Horm Cancer. 2013 Jun;4(3):176-85.
Title: Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles.
Author: Yalcin, Murat|Lin, Hung-Yun|Sudha, Thangirala|Bharali, Dhruba J|Meng, Ran|Tang, Heng-Yuan|Davis, Faith B|Stain, Steven C|Davis, Paul J|Mousa, Shaker A
PMID: 23456390
Journal: J Proteome Res. 2014 Apr 4;13(4):1873-84.
Title: Glycoprotein biomarker panel for pancreatic cancer discovered by quantitative proteomics analysis.
Author: Nie, Song|Lo, Andy|Wu, Jing|Zhu, Jianhui|Tan, Zhijing|Simeone, Diane M|Anderson, Michelle A|Shedden, Kerby A|Ruffin, Mack T|Lubman, David M
PMID: 24571389
Journal: J Proteome Res. 2014 Dec 5;13(12):6058-66.
Title: Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method.
Author: Nie, Song|Yin, Haidi|Tan, Zhijing|Anderson, Michelle A|Ruffin, Mack T|Simeone, Diane M|Lubman, David M
PMID: 25393578
Journal: Oncotarget. 2015 Jul 20;6(20):17981-8000.
Title: Identification of TAX2 peptide as a new unpredicted anti-cancer agent.
Author: Jeanne, Albin|Sick, Emilie|Devy, Jerome|Floquet, Nicolas|Belloy, Nicolas|Theret, Louis|Boulagnon-Rombi, Camille|Diebold, Marie-Daniele|Dauchez, Manuel|Martiny, Laurent|Schneider, Christophe|Dedieu, Stephane
PMID: 26046793
Journal: Clin Cancer Res. 2016 Apr 1;22(7):1734-1743.
Title: Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus.
Author: Jenkinson, Claire|Elliott, Victoria L|Evans, Anthony|Oldfield, Lucy|Jenkins, Rosalind E|O'Brien, Darragh P|Apostolidou, Sophia|Gentry-Maharaj, Aleksandra|Fourkala, Evangelia-O|Jacobs, Ian J|Menon, Usha|Cox, Trevor|Campbell, Fiona|Pereira, Stephen P|Tuveso
PMID: 26573598
Journal: J Clin Invest. 2016 Nov 1;126(11):4140-4156.
Title: Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.
Author: Leca, Julie|Martinez, Sebastien|Lac, Sophie|Nigri, Jeremy|Secq, Veronique|Rubis, Marion|Bressy, Christian|Serge, Arnauld|Lavaut, Marie-Noelle|Dusetti, Nelson|Loncle, Celine|Roques, Julie|Pietrasz, Daniel|Bousquet, Corinne|Garcia, Stephane|Granjeaud, Samue
PMID: 27701147
Journal: Pediatr Res. 2017 Mar;81(3):480-488.
Title: Thrombospondin-targeting TAX2 peptide impairs tumor growth in preclinical mouse models of childhood neuroblastoma.
Author: Jeanne, Albin|Martiny, Laurent|Dedieu, Stephane
PMID: 27842053
Journal: Eur J Cancer. 2017 Jul;80:5-13.
Title: A combination of platelet features allows detection of early-stage cancer.
Author: Sabrkhany, Siamack|Kuijpers, Marijke J E|van Kuijk, Sander M J|Sanders, Linda|Pineda, Sharo|Olde Damink, Steven W M|Dingemans, Anne-Marie C|Griffioen, Arjan W|Oude Egbrink, Mirjam G A
PMID: 28527393
Journal: Mol Med Rep. 2018 Jan;17(1):216-224.
Title: Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes.
Author: Zheng, Bingli|Peng, Jie|Mollayup, Ablikim|Bakri, Ahmat|Guo, Lei|Zheng, Jianjiang|Xu, Hui
PMID: 29115420