Primary Site >> Stomach Cancer

Gene >> THBS1

Journal: Cancer Res. 2001 Apr 1;61(7):2847-51.
Title: CpG island methylation in premalignant stages of gastric carcinoma.
Author: Kang, G H|Shim, Y H|Jung, H Y|Kim, W H|Ro, J Y|Rhyu, M G
PMID: 11306456
Journal: J Biol Chem. 2001 May 25;276(21):17932-40. Epub 2001 Mar 2.
Title: Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats.
Author: Cal, S|Arguelles, J M|Fernandez, P L|Lopez-Otin, C
PMID: 11279086
Journal: J Surg Res. 2002 Nov;108(1):51-60.
Title: Up-regulation of matrix metalloproteinase 9 by thrombospondin 1 in gastric cancer.
Author: Albo, Daniel|Shinohara, Tetsuo|Tuszynski, George P
PMID: 12443715
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2002 Oct;23(5):374-7.
Title: [Study on the Relationship between susceptibility of stomach neoplasm cancer and polymorphism of inducible nitric oxide synthase gene].
Author: Shen, Jing|Wang, Runtian|Wang, Liwei|Wang, Zhaoxi|Xing, Houxun|Wang, Binyan|Li, Maosen|Hua, Zhaolai|Wang, Jianming|Guo, Chunhua|Wang, Xinru|Xu, Xiping
PMID: 12482371
Journal: Am J Pathol. 2002 Mar;160(3):787-94.
Title: Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Woo Ho|Lee, Hye Won|Kim, Jin Cheon|Rhyu, Mun-Gan|Ro, Jae Y
PMID: 11891177
Journal: Lab Invest. 2003 Apr;83(4):519-26.
Title: Profile of aberrant CpG island methylation along multistep gastric carcinogenesis.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Jung-Sun|Jung, Hwoon-Yong
PMID: 12695555
Journal: Virchows Arch. 2003 Jun;442(6):563-8.
Title: Expression of thrombospondin-1 is correlated with microvessel density in gastric carcinoma.
Author: Zhang, Jie|Ito, Reiko|Oue, Naohide|Zhu, Xudong|Kitadai, Yasuhiko|Yoshida, Kazuhiro|Nakayama, Hirofumi|Yasui, Wataru
PMID: 12719977
Journal: Lab Invest. 2003 May;83(5):635-41.
Title: Profile of aberrant CpG island methylation along the multistep pathway of gastric carcinogenesis.
Author: Kang, Gyeong Hoon|Lee, Sun|Kim, Jung-Sun|Jung, Hwoon-Yong
PMID: 12746473
Journal: Oncology. 2003;64(4):423-9.
Title: Reduced expression of the TSP1 gene and its association with promoter hypermethylation in gastric carcinoma.
Author: Oue, Naohide|Matsumura, Shunji|Nakayama, Hirofumi|Kitadai, Yasuhiko|Taniyama, Kiyomi|Matsusaki, Keisuke|Yasui, Wataru
PMID: 12759541
Journal: Am J Pathol. 2003 Oct;163(4):1551-6.
Title: Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation.
Author: Kang, Gyeong Hoon|Lee, Hyeon Joo|Hwang, Kyu Sang|Lee, Sun|Kim, Jae-Hoon|Kim, Jung-Sun
PMID: 14507661
Journal: Am J Pathol. 2004 Feb;164(2):689-99.
Title: Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.
Author: Etoh, Tsuyoshi|Kanai, Yae|Ushijima, Saori|Nakagawa, Tohru|Nakanishi, Yukihiro|Sasako, Mitsuru|Kitano, Seigo|Hirohashi, Setsuo
PMID: 14742272
Journal: J Cancer Res Clin Oncol. 2005 Nov;131(11):733-40. Epub 2005 Nov 1.
Title: Aberrant CpG island methylation in early-onset sporadic gastric carcinoma.
Author: Kim, Hee Cheol|Kim, Jin Cheon|Roh, Sun Ae|Yu, Chang Sik|Yook, Jeong Hwan|Oh, Sung Tae|Kim, Byung Sik|Park, Kun Choon|Chang, Rin
PMID: 16075282
Journal: Biochem Biophys Res Commun. 2006 Jun 16;344(4):1284-9. Epub 2006 Apr 21.
Title: IL-18 enhances thrombospondin-1 production in human gastric cancer via JNK pathway.
Author: Kim, Jihye|Kim, Cherlhyun|Kim, Tae Sung|Bang, Sa Ik|Yang, Young|Park, Hyunjeong|Cho, Daeho
PMID: 16650813
Journal: Cancer Sci. 2006 Sep;97(9):938-44. Epub 2006 Jun 29.
Title: Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.
Author: Zhang, Xiaotian|Yashiro, Masakazu|Ohira, Masaichi|Ren, Jun|Hirakawa, Kosei
PMID: 16805821
Journal: Cancer Lett. 2007 Aug 28;254(1):42-53. Epub 2007 Mar 19.
Title: Differential expression of angiogenesis-related genes in human gastric cancers with and those without high-frequency microsatellite instability.
Author: Miyamoto, Nobuki|Yamamoto, Hiroyuki|Taniguchi, Hiroaki|Miyamoto, Chie|Oki, Mariko|Adachi, Yasushi|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 17374440
Journal: J Natl Cancer Inst. 2009 Apr 15;101(8):592-604.
Title: Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling.
Author: Komuro, Akiyoshi|Yashiro, Masakazu|Iwata, Caname|Morishita, Yasuyuki|Johansson, Erik|Matsumoto, Yoshiko|Watanabe, Akira|Aburatani, Hiroyuki|Miyoshi, Hiroyuki|Kiyono, Kunihiko|Shirai, Yo-taro|Suzuki, Hiroshi I|Hirakawa, Kosei|Kano, Mitsunobu R|Miyazono, Ko
PMID: 19351925
Journal: Oncol Rep. 2009 May;21(5):1251-9.
Title: Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma.
Author: Kim, Ji Hun|Jung, Eun Ji|Lee, Hye Seung|Kim, Min A|Kim, Woo Ho
PMID: 19360301
Journal: Cancer Sci. 2009 Oct;100(10):1809-16.
Title: c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma.
Author: Kiyono, Kunihiko|Suzuki, Hiroshi I|Morishita, Yasuyuki|Komuro, Akiyoshi|Iwata, Caname|Yashiro, Masakazu|Hirakawa, Kosei|Kano, Mitsunobu R|Miyazono, Kohei
PMID: 19594546
Journal: Mol Med Rep. 2010 Nov-Dec;3(6):1071-8.
Title: Expression of taxol resistance gene 1 correlates with gastric cancer patient clinical outcome and induces taxol resistance.
Author: Bai, Zhi-Gang|Qu, Xiang|Han, Wei|Ma, Xue-Mei|Zhao, Xiao-Mu|Zhang, Zhong-Tao
PMID: 21472357
Journal: Biomed Pharmacother. 2010 Feb;64(2):133-9.
Title: Gene expression profile towards the prediction of patient survival of gastric cancer.
Author: Xu, Zhen-Yu|Chen, Jia-Shun|Shu, Yong-Qian
PMID: 20005068
Journal: Int J Oncol. 2010 May;36(5):1193-200.
Title: The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells.
Author: Matsushita, Shigeto|Ikeda, Ryuji|Nishizawa, Yukihiko|Che, Xiao-Fang|Furukawa, Tatsuhiko|Miyadera, Kazutaka|Tabata, Sho|Ushiyama, Mina|Tajitsu, Yusuke|Yamamoto, Masatatsu|Takeda, Yasuo|Minami, Kentaro|Mataki, Hironori|Kanzaki, Tamotsu|Yamada, Katsushi|Kane
PMID: 20372793
Journal: Int J Clin Oncol. 2011 Apr;16(2):145-52.
Title: Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer.
Author: Nakao, Toshihiro|Kurita, Nobuhiro|Komatsu, Masato|Yoshikawa, Kozo|Iwata, Takashi|Utsunomiya, Toru|Shimada, Mitsuo
PMID: 21107877
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):879-87.
Title: Metronomic docetaxel chemotherapy inhibits angiogenesis and tumor growth in a gastric cancer model.
Author: Wu, Hongju|Xin, Yan|Zhao, Jing|Sun, Dan|Li, Wenhui|Hu, Yueyun|Wang, Shasha
PMID: 21290245
Journal: DNA Cell Biol. 2012 Apr;31(4):511-9.
Title: Polymorphism of THBS1 rs1478604 A>G in 5-untranslated region is associated with lymph node metastasis of gastric cancer in a Southeast Chinese population.
Author: Lin, Xian-Dong|Chen, Shu-Qin|Qi, Yuan-Lin|Zhu, Jin-Wei|Tang, Yang|Lin, Jian-Yin
PMID: 22011138
Journal: J Surg Oncol. 2012 Jul 1;106(1):94-100.
Title: Overexpression of thrombospondin-1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma.
Author: Lin, Xian-Dong|Chen, Shu-Qin|Qi, Yuan-Lin|Zhu, Jin-Wei|Tang, Yang|Lin, Jian-Yin
PMID: 22231149
Journal: Int J Cancer. 2013 Jan 15;132(2):485-94.
Title: An armed oncolytic herpes simplex virus expressing thrombospondin-1 has an enhanced in vivo antitumor effect against human gastric cancer.
Author: Tsuji, Toshiaki|Nakamori, Mikihito|Iwahashi, Makoto|Nakamura, Masaki|Ojima, Toshiyasu|Iida, Takeshi|Katsuda, Masahiro|Hayata, Keiji|Ino, Yasushi|Todo, Tomoki|Yamaue, Hiroki
PMID: 22729516
Journal: Dig Dis Sci. 2013 Feb;58(2):405-13.
Title: Expression of ADAMTS1 and its correlation with angiogenesis in primary gastric cancer and lymph node metastasis.
Author: Chen, Jing|Zhi, Yu|Chang, Xiaojing|Zhang, Shuanglong|Dai, Dongqiu
PMID: 23001403
Journal: Dig Dis Sci. 2013 Oct;58(10):2850-7.
Title: Methylation pattern of THBS1, GATA-4, and HIC1 in pediatric and adult patients infected with Helicobacter pylori.
Author: Alvarez, Marisa Claudia|Ladeira, Marcelo Sady Placido|Scaletsky, Isabel Cristina Affonso|Pedrazzoli, Jose Jr|Ribeiro, Marcelo Lima
PMID: 23765259
Journal: Med Oncol. 2014 Feb;31(2):807.
Title: Txr1: an important factor in oxaliplatin resistance in gastric cancer.
Author: Bi, Jingtao|Bai, Zhigang|Ma, Xuemei|Song, Jianning|Guo, Yantong|Zhao, Jingming|Yi, Xin|Han, Shiwei|Zhang, Zhongtao
PMID: 24362794
Journal: Tumour Biol. 2014 Feb;35(2):1107-11.
Title: Association of COX2 gene hypomethylation with intestinal type gastric cancer in samples of patients from northern Brazil.
Author: de Melo, Cynthia Farias Vieira|Gigek, Carolina Oliveira|da Silva, Juarez Nobrega|Cardoso Smith, Marilia de Arruda|de Araujo, Rubistenia Miranda|Burbano, Rommel Rodriguez|Lima, Eleonidas Moura
PMID: 24014049
Journal: Anticancer Res. 2015 Apr;35(4):2071-6.
Title: The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer.
Author: Eto, Shohei|Yoshikawa, Kozo|Shimada, Mitsuo|Higashijima, Jun|Tokunaga, Takuya|Nakao, Toshihiro|Nishi, Masaaki|Takasu, Chie|Sato, Hirohiko|Kurita, Nobuhiro
PMID: 25862862
Journal: Biomed Rep. 2015 Mar;3(2):207-214.
Title: Association of THBS1 rs1478605 T>C in 5'-untranslated regions with the development and progression of gastric cancer.
Author: Hong, Bin-Bin|Chen, Shu-Qin|Qi, Yuan-Lin|Zhu, Jin-Wei|Lin, Jian-Yin
PMID: 26075074
Journal: Mol Med Rep. 2015 Nov;12(5):7139-45.
Title: A systems biology approach to detect key pathways and interaction networks in gastric cancer on the basis of microarray analysis.
Author: Guo, Leilei|Song, Chunhua|Wang, Peng|Dai, Liping|Zhang, Jianying|Wang, Kaijuan
PMID: 26324226
Journal: Biomed Res Int. 2015;2015:741030.
Title: The diagnosis value of promoter methylation of UCHL1 in the serum for progression of gastric cancer.
Author: Wang, Gongping|Zhang, Wei|Zhou, Bo|Jin, Canhui|Wang, Zengfang|Yang, Yantong|Wang, Zhenzhen|Chen, Ye|Feng, Xiaoshan
PMID: 26550574
Journal: Exp Ther Med. 2016 Mar;11(3):846-852.
Title: Effects of taxol resistance gene 1 expression on the chemosensitivity of SGC-7901 cells to oxaliplatin.
Author: Liu, Liancheng|Bai, Zhigang|Ma, Xuemei|Wang, Tingting|Yang, Yao|Zhang, Zhongtao
PMID: 26998002
Journal: Clin Cancer Res. 2016 Dec 15;22(24):6228-6235.
Title: Development and Validation of a Six-Gene Recurrence Risk Score Assay for Gastric Cancer.
Author: Lee, Keun-Wook|Lee, Sung Sook|Hwang, Jun-Eul|Jang, Hee-Jin|Lee, Hyun-Sung|Oh, Sang Cheul|Lee, Sang Ho|Sohn, Bo Hwa|Kim, Sang Bae|Shim, Jae-Jun|Jeong, Woojin|Cha, Minse|Cheong, Jae-Ho|Cho, Jae Yong|Lim, Jae Yun|Park, Eun Sung|Kim, Sang Cheol|Kang, Yoon-Koo
PMID: 27654712
Journal: Oncol Lett. 2016 Oct;12(4):2345-2350.
Title: Celecoxib exhibits an anti-gastric cancer effect by targeting focal adhesion and leukocyte transendothelial migration-associated genes.
Author: Jin, Guo-Hua|Xu, Wei|Shi, Yang|Wang, Li-Bo
PMID: 27698798
Journal: Proteomics. 2017 Mar;17(6).
Title: Discovery of gastric cancer specific biomarkers by the application of serum proteomics.
Author: Yoo, Moon-Won|Park, Jisook|Han, Hye-Seung|Yun, Yeo-Min|Kang, Jeong Won|Choi, Do-Young|Lee, Joon Won|Jung, Jae Hun|Lee, Kyung-Yung|Kim, Kwang Pyo
PMID: 28133907
Journal: Int J Oncol. 2017 May;50(5):1501-1512.
Title: FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1.
Author: Huang, Tingting|Wang, Lei|Liu, Dian|Li, Piao|Xiong, Huihua|Zhuang, Liang|Sun, Li|Yuan, Xianglin|Qiu, Hong
PMID: 28339036
Journal: Anticancer Res. 2017 Jul;37(7):3547-3552.
Title: Correlation Between Thrombospondin-1 Expression in Non-cancer Tissue and Gastric Carcinogenesis.
Author: Kashihara, Hideya|Shimada, Mitsuo|Yoshikawa, Kozo|Higashijima, Jun|Tokunaga, Takuya|Nishi, Masaaki|Takasu, Chie|Ishikawa, Daichi
PMID: 28668845