Primary Site >> Stomach Cancer

Gene >> TGFBR2

Journal: Int J Cancer. 1996 Oct 9;68(2):203-6.
Title: Mutations of the transforming growth factor beta type II receptor gene and microsatellite instability in gastric cancer.
Author: Ohue, M|Tomita, N|Monden, T|Miyoshi, Y|Ohnishi, T|Izawa, H|Kawabata, Y|Sasaki, M|Sekimoto, M|Nishisho, I|Shiozaki, H|Monden, M
PMID: 8900429
Journal: Cancer Res. 1997 Jul 15;57(14):2856-9.
Title: Expression of transforming growth factor beta type II receptor reduces tumorigenicity in human gastric cancer cells.
Author: Chang, J|Park, K|Bang, Y J|Kim, W S|Kim, D|Kim, S J
PMID: 9230189
Journal: Oncol Rep. 1998 Jan-Feb;5(1):77-80.
Title: Absence of mutatins in the analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic humangastric cancer using genomic DNA and intron primers.
Author: Takenoshita, S|Mogi, A|Osawa, H|Sunaga, H|Kakegawa, H|Tani, M|Morinaga, N|Kato, R|Hagiwara, K|Nagamachi, Y
PMID: 9458298
Journal: Oncol Rep. 1998 Mar-Apr;5(2):367-71.
Title: Absence of mutations in the analysis of coding sequences of the entire transforming growth factor-beta type II receptor gene in sporadic human breast cancers.
Author: Takenoshita, S|Mogi, A|Tani, M|Osawa, H|Sunaga, H|Kakegawa, H|Yanagita, Y|Koida, T|Kimura, M|Fujita, K I|Kato, H|Kato, R|Nagamachi, Y
PMID: 9468559
Journal: Carcinogenesis. 1998 Sep;19(9):1539-44.
Title: Analyses of mutation and loss of heterozygosity of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human gastric cancer.
Author: Guo, R J|Wang, Y|Kaneko, E|Wang, D Y|Arai, H|Hanai, H|Takenoshita, S|Hagiwara, K|Harris, C C|Sugimura, H
PMID: 9771922
Journal: Genes Chromosomes Cancer. 1998 Dec;23(4):317-22.
Title: Infrequent frameshift mutations of polynucleotide repeats in multiple primary cancers affecting the esophagus and other organs.
Author: Iwaya, T|Maesawa, C|Nishizuka, S|Suzuki, Y|Sakata, K|Sato, N|Ikeda, K|Koeda, K|Ogasawara, S|Otsuka, K|Kimura, Y|Aoki, K|Ishida, K|Saito, K|Tamura, G
PMID: 9824204
Journal: Br J Cancer. 1999 Feb;79(3-4):582-8.
Title: Microsatellite instability, Epstein-Barr virus, mutation of type II transforming growth factor beta receptor and BAX in gastric carcinomas in Hong Kong Chinese.
Author: Leung, S Y|Yuen, S T|Chung, L P|Chu, K M|Wong, M P|Branicki, F J|Ho, J C
PMID: 10027334
Journal: Lab Invest. 1999 Sep;79(9):1113-20.
Title: Accumulated frameshift mutations at coding nucleotide repeats during the progression of gastric carcinoma with microsatellite instability.
Author: Kim, J J|Baek, M J|Kim, L|Kim, N G|Lee, Y C|Song, S Y|Noh, S H|Kim, H
PMID: 10496529
Journal: Eur J Surg Oncol. 2000 Jun;26(4):377-80.
Title: The progression of invasiveness regarding the role of transforming growth factor beta receptor type II in gastric cancer.
Author: Tateishi, M|Kusaba, I|Masuda, H|Tanaka, T|Matsumata, T|Sugimachi, K
PMID: 10873359
Journal: Oncogene. 2001 Mar 8;20(10):1235-45.
Title: Sequence-specific enhancer binding protein is responsible for the differential expression of ERT/ESX/ELF-3/ESE-1/jen gene in human gastric cancer cell lines: Implication for the loss of TGF-beta type II receptor expression.
Author: Park, S H|Kim, Y S|Park, B K|Hougaard, S|Kim, S J
PMID: 11313868
Journal: Tumour Biol. 2001 Jul-Aug;22(4):262-8.
Title: Absence of microsatellite instability and germline mutations of E-cadherin, APC and p53 genes in Japanese familial gastric cancer.
Author: Kusano, M|Kakiuchi, H|Mihara, M|Itoh, F|Adachi, Y|Ohara, M|Hosokawa, M|Imai, K
PMID: 11399952
Journal: Korean J Intern Med. 2002 Sep;17(3):160-6.
Title: Role of TGF-beta 1 and TGF-beta type II receptor in gastric cancer.
Author: Park, Dong 2nd|Son, Hee Jung|Song, Sang Yong|Choe, Won Hyeok|Lim, Yun Jeong|Park, Sang Jong|Kim, Jae J|Kim, Young Ho|Rhee, Poong Lyul|Paik, Seung Woon|Rhee, Jong Chul|Choi, Kyoo Wan
PMID: 12353499
Journal: Mol Cancer Res. 2004 Mar;2(3):183-95.
Title: Cystatin C antagonizes transforming growth factor beta signaling in normal and cancer cells.
Author: Sokol, Jonathan P|Schiemann, William P
PMID: 15037657
Journal: Gastroenterology. 2005 Mar;128(3):590-9.
Title: HNPCC-associated small bowel cancer: clinical and molecular characteristics.
Author: Schulmann, Karsten|Brasch, Frank E|Kunstmann, Erdmute|Engel, Christoph|Pagenstecher, Constanze|Vogelsang, Holger|Kruger, Stefan|Vogel, Tilman|Knaebel, Hanns-Peter|Ruschoff, Josef|Hahn, Stephan A|Knebel-Doeberitz, Magnus V|Moeslein, Gabriela|Meltzer, Steph
PMID: 15765394
Journal: Ai Zheng. 2007 Jun;26(6):581-5.
Title: [Correlations of polymorphisms of TGFB1 and TGFBR2 genes to genetic susceptibility to gastric cancer].
Author: Zhou, Yan|Jin, Guang-Fu|Jiang, Guo-Jun|Wang, Hong-Min|Tan, Yong-Fei|Ding, Wei-Liang|Wang, Li-Na|Chen, Wen-Sen|Ke, Qiao|Shen, Jing|Xu, Yao-Chu|Shen, Hong-Bing
PMID: 17562261
Journal: Int J Cancer. 2007 Mar 15;120(6):1330-5.
Title: Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population.
Author: Jin, Guangfu|Wang, Lina|Chen, Wensen|Hu, Zhibin|Zhou, Yan|Tan, Yongfei|Wang, Jianming|Hua, Zhaolai|Ding, Weiliang|Shen, Jing|Zhang, Zuofeng|Wang, Xinru|Xu, Yaochu|Shen, Hongbing
PMID: 17187359
Journal: Oncogene. 2007 Oct 4;26(45):6488-98. Epub 2007 Apr 30.
Title: GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling.
Author: Saeki, N|Kim, D H|Usui, T|Aoyagi, K|Tatsuta, T|Aoki, K|Yanagihara, K|Tamura, M|Mizushima, H|Sakamoto, H|Ogawa, K|Ohki, M|Shiroishi, T|Yoshida, T|Sasaki, H
PMID: 17471240
Journal: J Cancer Res Clin Oncol. 2008 Mar;134(3):345-51. Epub 2007 Aug 7.
Title: TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case-control analysis in a Chinese population.
Author: Jin, Guangfu|Deng, Yimei|Miao, Ruifen|Hu, Zhibin|Zhou, Yan|Tan, Yongfei|Wang, Jianming|Hua, Zhaolai|Ding, Weiliang|Wang, Lina|Chen, Wensen|Shen, Jing|Wang, Xinru|Xu, Yaochu|Shen, Hongbing
PMID: 17680270
Journal: Histol Histopathol. 2008 Dec;23(12):1439-52.
Title: Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence.
Author: Kim, Seok-Hyung|Lee, Seung-Hyun|Choi, Yoon-La|Wang, Li-Hui|Park, Cheol Keun|Shin, Young Kee
PMID: 18830930
Journal: Ai Zheng. 2009 May;28(5):538-42.
Title: [Correlations of TGF-betaRII, Smad4 and Smad7 expression to clinicopathologic characteristics and prognosis of gastric cancer].
Author: Lu, Bin|Zhou, Yong-Ning|Li, Qiang|Wu, Zheng-Qi|Zhang, Zhi-Yi|Ji, Rui|Guo, Qing-Hong|Liu, Wei
PMID: 19624886
Journal: Oncol Lett. 2011 Mar;2(2):371-377.
Title: Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control study.
Author: Xu, Lixia|Zeng, Zhirong|Chen, Bin|Wu, Xiaoqin|Yu, Jun|Xue, Ling|Tian, Linwei|Wang, Yiming|Chen, Minhu|Sung, Joseph J Y|Hu, Pinjin
PMID: 22866090
Journal: Braz J Med Biol Res. 2014 May;47(5):369-75.
Title: Transduction motif analysis of gastric cancer based on a human signaling network.
Author: Liu, G|Li, D Z|Jiang, C S|Wang, W
PMID: 24838641
Journal: Genome Biol. 2014 Aug 27;15(8):444.
Title: One patient, two lesions, two oncogenic drivers of gastric cancer.
Author: Alsinet, Clara|Ranzani, Marco|Adams, David J
PMID: 25222187
Journal: Genome Biol. 2014 Aug 27;15(8):428.
Title: Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.
Author: Nadauld, Lincoln D|Garcia, Sarah|Natsoulis, Georges|Bell, John M|Miotke, Laura|Hopmans, Erik S|Xu, Hua|Pai, Reetesh K|Palm, Curt|Regan, John F|Chen, Hao|Flaherty, Patrick|Ootani, Akifumi|Zhang, Nancy R|Ford, James M|Kuo, Calvin J|Ji, Hanlee P
PMID: 25315765
Journal: Genes Chromosomes Cancer. 2015 Mar;54(3):142-55.
Title: Homozygous deletions at 3p22, 5p14, 6q15, and 9p21 result in aberrant expression of tumor suppressor genes in gastric cancer.
Author: Lee, Bona|Yoon, Kwiyeom|Lee, Sunghoon|Kang, Jin Muk|Kim, Junil|Shim, Sung Han|Kim, Hak-Min|Song, Sanghoon|Naka, Kazuhito|Kim, An Keun|Yang, Han-Kwang|Kim, Seong-Jin
PMID: 25521327
Journal: Gut. 2015 Aug;64(8):1209-19.
Title: Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.
Author: Mocellin, Simone|Verdi, Daunia|Pooley, Karen A|Nitti, Donato
PMID: 25731870
Journal: Arch Toxicol. 2015 Jun;89(6):899-921.
Title: Microsatellite instability: an update.
Author: Yamamoto, Hiroyuki|Imai, Kohzoh
PMID: 25701956
Journal: Oncotarget. 2016 May 31;7(22):33286-96.
Title: MiR-17-5p regulates cell proliferation and migration by targeting transforming growth factor-beta receptor 2 in gastric cancer.
Author: Qu, Yanjun|Zhang, Haiyang|Duan, Jingjing|Liu, Rui|Deng, Ting|Bai, Ming|Huang, Dingzhi|Li, Hongli|Ning, Tao|Zhang, Le|Wang, Xia|Ge, Shaohua|Zhou, Likun|Zhong, Benfu|Ying, Guoguang|Ba, Yi
PMID: 27120811
Journal: Oncotarget. 2016 Jul 12;7(28):44522-44533.
Title: Onco-miR-130 promotes cell proliferation and migration by targeting TGFbetaR2 in gastric cancer.
Author: Duan, Jingjing|Zhang, Haiyang|Qu, Yanjun|Deng, Ting|Huang, Dingzhi|Liu, Rui|Zhang, Le|Bai, Ming|Zhou, Likun|Ying, Guoguang|Ba, Yi
PMID: 27304191
Journal: Am J Cancer Res. 2017 Jul 1;7(7):1540-1553. eCollection 2017.
Title: Genomic alterations in advanced gastric cancer endoscopic biopsy samples using targeted next-generation sequencing.
Author: Ge, Sai|Li, Beifang|Li, Yanyan|Li, Zhongwu|Liu, Zhentao|Chen, Zuhua|Wu, Jian|Gao, Jing|Shen, Lin
PMID: 28744403
Journal: Cancer Sci. 2018 Mar;109(3):618-628.
Title: MicroRNA-155 promotes gastric cancer growth and invasion by negatively regulating transforming growth factor-beta receptor 2.
Author: Qu, Yajing|Zhang, Haiyang|Sun, Wu|Han, Yueting|Li, Shuang|Qu, Yanjun|Ying, Guoguang|Ba, Yi
PMID: 29247570
Journal: Neoplasma. 2018 Mar 14;65(3):360-366.
Title: Identification of recurrent risk-related genes and establishment of support vector machine prediction model for gastric cancer.
Author: Liu, B|Tan, J|Wang, X|Liu, X
PMID: 29788739
Journal: Cell Physiol Biochem. 2018;47(4):1533-1545.
Title: Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition.
Author: Li, Liang-Qing|Pan, Dun|Chen, Qun|Zhang, Sheng-Wei|Xie, Di-Ya|Zheng, Xue-Lan|Chen, Hui
PMID: 29940566