Primary Site >> Stomach Cancer

Gene >> TFF3

Journal: Eur J Hum Genet. 1996;4(6):308-15.
Title: Human trefoil peptides: genomic structure in 21q22.3 and coordinated expression.
Author: Gott, P|Beck, S|Machado, J C|Carneiro, F|Schmitt, H|Blin, N
PMID: 9043862
Journal: FEBS Lett. 1997 May 19;408(2):121-3.
Title: Rolling in the clover: trefoil factor family (TFF)-domain peptides, cell migration and cancer.
Author: Wright, N A|Hoffmann, W|Otto, W R|Rio, M C|Thim, L
PMID: 9187350
Journal: FEBS Lett. 1998 Nov 13;439(1-2):180-4.
Title: Osmotic changes and ethanol modify TFF gene expression in gastrointestinal cell lines.
Author: Ludeking, A|Fegert, P|Blin, N|Gott, P
PMID: 9849902
Journal: FEBS Lett. 2001 Jan 19;488(3):206-10.
Title: Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.
Author: Azarschab, P|Al-Azzeh, E|Kornberger, W|Gott, P
PMID: 11163773
Journal: Lab Invest. 2001 Mar;81(3):397-408.
Title: Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium.
Author: Taupin, D|Pedersen, J|Familari, M|Cook, G|Yeomans, N|Giraud, A S
PMID: 11310832
Journal: Clin Cancer Res. 2002 May;8(5):1092-9.
Title: Intestinal trefoil factor: a marker of poor prognosis in gastric carcinoma.
Author: Yamachika, Takasuke|Werther, J Lawrence|Bodian, Carol|Babyatsky, Mark|Tatematsu, Masae|Yamamura, Yoshitaka|Chen, Anli|Itzkowitz, Steven
PMID: 12006524
Journal: Int J Oncol. 2002 Sep;21(3):655-9.
Title: Expression of TFF1, TFF2 and TFF3 in gastric cancer.
Author: Kirikoshi, Hiroyuki|Katoh, Masaru
PMID: 12168114
Journal: J Pathol. 2002 Aug;197(5):582-8.
Title: Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues.
Author: Leung, Wai K|Yu, Jun|Chan, Francis K L|To, Ka F|Chan, Michael W Y|Ebert, M P A|Ng, Enders K W|Chung, S C Sydney|Malfertheiner, Peter|Sung, Joseph J Y
PMID: 12210076
Journal: Mol Cancer Ther. 2002 Apr;1(6):405-15.
Title: Coordinate late expression of trefoil peptide genes (pS2/TFF1 and ITF/TFF3) in human breast, colon, and gastric tumor cells exposed to X-rays.
Author: Balcer-Kubiczek, Elizabeth K|Harrison, George H|Xu, Jing-Fan|Gutierrez, Peter L
PMID: 12477053
Journal: Int J Mol Med. 2003 Jul;12(1):3-9.
Title: Trefoil factors and human gastric cancer (review).
Author: Katoh, Masaru
PMID: 12792801
Journal: Genomics. 2003 Jul;82(1):78-85.
Title: Analysis of gene expression profiles of gastric normal and cancer tissues by SAGE.
Author: Lee, Ji-Yeon|Eom, Eun-Mi|Kim, Dae-Sik|Ha-Lee, Young Mie|Lee, Dong-Hee
PMID: 12809678
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:171-6.
Title: Indometacin up-regulates TFF2 expression in gastric epithelial cells.
Author: Koitabashi, A|Shimada, T|Fujii, Y|Hashimoto, T|Hosaka, K|Tabei, K|Namatame, T|Yoneda, M|Hiraishi, H|Terano, A
PMID: 15298624
Journal: J Gastroenterol Hepatol. 2005 Aug;20(8):1266-78.
Title: Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors.
Author: Judd, Louise M|Andringa, Anastasia|Rubio, Carlos A|Spicer, Zachary|Shull, Gary E|Miller, Marian L
PMID: 16048577
Journal: Bull Cancer. 2005 Sep;92(9):773-81.
Title: [Trefoil factor 1 (pS2/TFF1), a peptide with numerous functions].
Author: Mathelin, Carole|Tomasetto, Catherine|Rio, Marie-Christine
PMID: 16203267
Journal: Clin Cancer Res. 2005 Sep 15;11(18):6472-8.
Title: Expression of trefoil factor family members correlates with patient prognosis and neoangiogenesis.
Author: Dhar, Dipok Kumar|Wang, Timothy C|Tabara, Hideki|Tonomoto, Yasuhito|Maruyama, Riruke|Tachibana, Mitsuo|Kubota, Hirofumi|Nagasue, Naofumi
PMID: 16166422
Journal: Life Sci. 2005 Apr 15;76(22):2581-92. Epub 2005 Jan 26.
Title: Anti-sense trefoil factor family-3 (intestinal trefoil factor) inhibits cell growth and induces chemosensitivity to adriamycin in human gastric cancer cells.
Author: Chan, Michael W Y|Chan, Victor Y W|Leung, Wai K|Chan, Ka K|To, Ka F|Sung, Joseph J Y|Chan, Francis K L
PMID: 15769482
Journal: Regul Pept. 2005 Apr 15;127(1-3):87-94.
Title: Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell.
Author: Chan, Victor Y W|Chan, Michael W Y|Leung, Wai-Keung|Leung, Po-Sing|Sung, Joseph J Y|Chan, Francis K L
PMID: 15680474
Journal: Dig Liver Dis. 2008 Jul;40(7):510-22.
Title: Biology of intestinal metaplasia in 2008: more than a simple phenotypic alteration.
Author: Gutierrez-Gonzalez, L|Wright, N A
PMID: 18400571
Journal: Clin Cancer Res. 2008 Jul 1;14(13):4161-7.
Title: Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis.
Author: Moss, Steven F|Lee, Jin-Woo|Sabo, Edmond|Rubin, Anna K|Rommel, John|Westley, Bruce R|May, Felicity E B|Gao, John|Meitner, Patricia A|Tavares, Rose|Resnick, Murray B
PMID: 18593995
Journal: Scand J Gastroenterol. 2008 Jan;43(1):25-33.
Title: Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells.
Author: Matsuda, Kazuyuki|Yamauchi, Kazuyoshi|Matsumoto, Takehisa|Sano, Kenji|Yamaoka, Yoshio|Ota, Hiroyoshi
PMID: 18938748
Journal: Int J Biochem Cell Biol. 2009 Mar;41(3):632-40.
Title: The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer.
Author: May, Felicity E B|Griffin, S Michael|Westley, Bruce R
PMID: 18722547
Journal: Int J Cancer. 2011 Dec 1;129(11):2611-20.
Title: MiR-9 downregulates CDX2 expression in gastric cancer cells.
Author: Rotkrua, Pichayanoot|Akiyama, Yoshimitsu|Hashimoto, Yutaka|Otsubo, Takeshi|Yuasa, Yasuhito
PMID: 21225631
Journal: J Gastroenterol. 2011 Jun;46(6):736-45.
Title: The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.
Author: Kaise, Mitsuru|Miwa, Jun|Tashiro, Jun|Ohmoto, Yasukazu|Morimoto, Shingo|Kato, Masayuki|Urashima, Mitsuyoshi|Ikegami, Masahiro|Tajiri, Hisao
PMID: 21455714
Journal: Gastroenterology. 2011 Sep;141(3):837-845.e1-7.
Title: Tests for serum levels of trefoil factor family proteins can improve gastric cancer screening.
Author: Aikou, Susumu|Ohmoto, Yasukazu|Gunji, Toshiaki|Matsuhashi, Nobuyuki|Ohtsu, Hiroshi|Miura, Hirona|Kubota, Kensuke|Yamagata, Yukinori|Seto, Yasuyuki|Nakajima, Atsushi|Goldenring, James R|Kaminishi, Michio|Nomura, Sachiyo
PMID: 21699780
Journal: Mol Biol Rep. 2012 Apr;39(4):4127-34.
Title: TFF3 mediated induction of VEGF via hypoxia in human gastric cancer SGC-7901 cells.
Author: Guleng, Bayasi|Han, Jia|Yang, Jin-Qiu|Huang, Qing-Wen|Huang, Jian-Kun|Yang, Xiao-Ning|Liu, Jing-Jing|Ren, Jian-Lin
PMID: 21769478
Journal: Gastric Cancer. 2013 Jul;16(3):329-37.
Title: Influence of Helicobacter pylori status and eradication on the serum levels of trefoil factors and pepsinogen test: serum trefoil factor 3 is a stable biomarker.
Author: Kaise, Mitsuru|Miwa, Jun|Fujimoto, Ai|Tashiro, Jun|Tagami, Daisuke|Sano, Hiromi|Ohmoto, Yasukazu
PMID: 22907485
Journal: PLoS One. 2013 Dec 16;8(12):e82136.
Title: Impact of NPM, TFF3 and TACC1 on the prognosis of patients with primary gastric cancer.
Author: Ding, Aiping|Zhao, Wenwen|Shi, Xiaoli|Yao, Ruyong|Zhou, Fang|Yue, Lu|Liu, Shihai|Qiu, Wensheng
PMID: 24358147
Journal: PLoS One. 2013 Nov 13;8(11):e79455.
Title: Copper promotes TFF1-mediated Helicobacter pylori colonization.
Author: Montefusco, Sandro|Esposito, Roberta|D'Andrea, Luca|Monti, Maria Chiara|Dunne, Ciara|Dolan, Brendan|Tosco, Alessandra|Marzullo, Liberato|Clyne, Marguerite
PMID: 24236136
Journal: Gene. 2013 Oct 15;529(1):104-12.
Title: Promoter polymorphisms in trefoil factor 2 and trefoil factor 3 genes and susceptibility to gastric cancer and atrophic gastritis among Chinese population.
Author: Xu, Qian|Chen, Mo-Ye|He, Cai-Yun|Sun, Li-Ping|Yuan, Yuan
PMID: 23933418
Journal: Pathol Res Pract. 2013 Aug;209(8):479-85.
Title: Significance of TFF3 protein and Her-2/neu status in patients with gastric adenocarcinoma.
Author: Xu, Cong-cong|Yue, Lu|Wei, Hong-jun|Zhao, Wen-wen|Sui, Ai-hua|Wang, Xiu-mei|Qiu, Wen-sheng
PMID: 23822993
Journal: Int J Med Sci. 2013;10(2):133-40.
Title: Reduced expression of TFF1 and increased expression of TFF3 in gastric cancer: correlation with clinicopathological parameters and prognosis.
Author: Im, Soyoung|Yoo, Changyoung|Jung, Ji-Han|Choi, Hyun Joo|Yoo, Jinyoung|Kang, Chang Suk
PMID: 23329884
Journal: Clin Exp Med. 2013 Nov;13(4):297-303.
Title: TFF3 and survivin expressions associate with a lower survival rate in gastric cancer.
Author: Meng, Jia-Rong|Tang, Hui-Zhong|Zhou, Kai-Zong|Shen, Wu-Hong|Guo, He-Yi
PMID: 22996285
Journal: Biochem Biophys Res Commun. 2013 Aug 16;438(1):6-12.
Title: Trefoil factor 3 peptide regulates migration via a Twist-dependent pathway in gastric cell.
Author: Zheng, Qianqian|Gao, Jian|Li, Honglin|Guo, Wendong|Mao, Qi|Gao, Enhui|Zhu, Ya-qin
PMID: 23845905
Journal: Oncogene. 2014 Jan 2;33(1):74-84.
Title: Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice.
Author: Inagaki-Ohara, K|Mayuzumi, H|Kato, S|Minokoshi, Y|Otsubo, T|Kawamura, Y I|Dohi, T|Matsuzaki, G|Yoshimura, A
PMID: 23178499
Journal: Cancer Prev Res (Phila). 2014 Jun;7(6):585-95.
Title: Slow overmethylation of housekeeping genes in the body mucosa is associated with the risk for gastric cancer.
Author: Oh, Jung-Hwan|Rhyu, Mun-Gan|Jung, Sung-Hoon|Choi, Sang-Wook|Kim, Suk-Il|Hong, Seung-Jin
PMID: 24654229
Journal: BMC Gastroenterol. 2014 Apr 11;14:74.
Title: Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China.
Author: Huang, Zhigang|Zhang, Xie|Lu, Hongna|Wu, Lina|Wang, Danping|Zhang, Qiubo|Ding, Huaxin
PMID: 24720760
Journal: Dig Dis Sci. 2014 Jul;59(7):1428-35.
Title: Piezo1 is as a novel trefoil factor family 1 binding protein that promotes gastric cancer cell mobility in vitro.
Author: Yang, Xiao-Ning|Lu, Ya-Pi|Liu, Jing-Jing|Huang, Jian-Kun|Liu, Yun-Peng|Xiao, Chuan-Xing|Jazag, Amarsanaa|Ren, Jian-Lin|Guleng, Bayasi
PMID: 24798994
Journal: PLoS One. 2014 Jun 13;9(6):e99835.
Title: Altered expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory genes in gastric cancer tissues.
Author: Wang, Jihan|Ni, Zhaohui|Duan, Zipeng|Wang, Guoqing|Li, Fan
PMID: 24927122
Journal: BMC Clin Pathol. 2014 Jun 14;14:26.
Title: Serum TFF3 may be a pharamcodynamic marker of responses to chemotherapy in gastrointestinal cancers.
Author: Xiao, Li|Liu, Yun-Peng|Xiao, Chuan-Xing|Ren, Jian-Lin|Guleng, Bayasi
PMID: 25031551
Journal: Mol Clin Oncol. 2014 Nov;2(6):1055-1061.
Title: Prognostic significance of the co-expression of nucleophosmin and trefoil factor 3 in postoperative gastric cancer patients.
Author: Li, Yong|Sun, Zhenqing|Liu, Kewei|Qiu, Wensheng|Yao, Ruyong|Feng, Tongtong|Xin, Chao|Yue, Lu
PMID: 25279197
Journal: Tumour Biol. 2015 Apr;36(4):3001-7.
Title: TFF3 and HER2 expression and their correlation with survival in gastric cancer.
Author: Gu, Jianchun|Zheng, Leizhen|Zhang, Li|Chen, Siyu|Zhu, Meiling|Li, Xiaoping|Wang, Yajie
PMID: 25514872
Journal: Clin Chim Acta. 2015 Oct 23;450:127-34.
Title: Trefoil factors: Gastrointestinal-specific proteins associated with gastric cancer.
Author: Xiao, Ping|Ling, Hui|Lan, Gang|Liu, Jiao|Hu, Haobin|Yang, Ruirui
PMID: 26265233
Journal: J Korean Med Sci. 2015 Aug;30(8):1035-41.
Title: Association between Promoter Polymorphisms of TFF1, TFF2, and TFF3 and the Risk of Gastric and Diffuse Gastric Cancers in a Korean Population.
Author: Jin, Eun-Heui|Lee, Sang-Il|Kim, JaeWoo|Seo, Eun Young|Lee, Su Yel|Hur, Gang Min|Shin, Sanghee|Hong, Jang Hee
PMID: 26240479
Journal: Gut. 2016 Jun;65(6):914-24.
Title: miR-30-HNF4gamma and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach.
Author: Sousa, Josane F|Nam, Ki Taek|Petersen, Christine P|Lee, Hyuk-Joon|Yang, Han-Kwang|Kim, Woo Ho|Goldenring, James R
PMID: 25800782
Journal: Clin Exp Med. 2017 Aug;17(3):403-410.
Title: Comparison of serum trefoil factor 3 with the pepsinogen test for the screening of diffuse-type gastric cancer.
Author: Lee, Ju Yup|Park, Kyung Sik|Lee, Hyun-Gyo|Baek, Won-Ki|Cho, Kwang Bum|Lee, Yoo Jin|Lee, Yoon Suk|Ryu, Seung-Wan
PMID: 27154568
Journal: Helicobacter. 2017 Feb;22(1).
Title: Serum Level of Trefoil Factor 2 can Predict the Extent of Gastric Spasmolytic Polypeptide-Expressing Metaplasia in the H. pylori-Infected Gastric Cancer Relatives.
Author: Kuo, Hsin-Yu|Chang, Wei-Lun|Yeh, Yi-Chun|Tsai, Yu-Ching|Wu, Chung-Tai|Cheng, Hsiu-Chi|Yang, Hsiao-Bai|Lu, Cheng-Chang|Sheu, Bor-Shyang
PMID: 27220894
Journal: Cancer Biomark. 2017 Jul 4;19(3):231-239.
Title: Plasma expression of the intestinal metaplasia markers CDH17 and TFF3 in patients with gastric cancer.
Author: Choi, Boram|Lee, Hyuk-Joon|Min, Jimin|Choe, Hwi-Nyeong|Choi, Yun-Suk|Son, Young-Gil|Ahn, Hye-Seong|Suh, Yun-Suhk|Goldenring, James R|Yang, Han-Kwang
PMID: 28453457
Journal: Pathol Int. 2017 Aug;67(8):398-403.
Title: Differences between gastric signet-ring cell carcinoma and poorly differentiated adenocarcinoma: A comparison of histopathologic features determined by mucin core protein and trefoil factor family peptide immunohistochemistry.
Author: Fujimoto, Ai|Ishikawa, Yukio|Ishii, Toshiharu|Yamada, Akihiro|Igarashi, Yoshinori|Ohmoto, Yasukazu|Kaise, Mitsuru
PMID: 28691258
Journal: Cancer Res Treat. 2018 Apr 30. pii: crt.2018.085.
Title: Gastric Mucosal Atrophy Impedes Housekeeping Gene Methylation in Gastric Cancer Patients.
Author: Oh, Jung-Hwan|Rhyu, Mun-Gan|Kim, Suk-Il|Yun, Mi-Ri|Shin, Jung-Ha|Hong, Seung-Jin
PMID: 29747491
Journal: Gastroenterol Res Pract. 2018 May 9;2018:1024074.
Title: Screening Biomarker as an Alternative to Endoscopy for the Detection of Early Gastric Cancer: The Combination of Serum Trefoil Factor Family 3 and Pepsinogen.
Author: Lee, Hyun Seok|Jeon, Seong Woo|Nomura, Sachiyo|Seto, Yasuyuki|Kwon, Yong Hwan|Nam, Su Youn|Ishibashi, Yuko|Ohtsu, Hiroshi|Ohmoto, Yasukazu|Yang, Hae Min
PMID: 29977284
Journal: World J Surg. 2018 Jul 23. pii: 10.1007/s00268-018-4737-0.
Title: Prognostic Value of Trefoil Factor 3 Expression in Patients with Gastric Cancer.
Author: Taniguchi, Yoshiki|Kurokawa, Yukinori|Takahashi, Tsuyoshi|Mikami, Jota|Miyazaki, Yasuhiro|Tanaka, Koji|Makino, Tomoki|Yamasaki, Makoto|Nakajima, Kiyokazu|Mori, Masaki|Doki, Yuichiro
PMID: 30039286