Primary Site >> Pancreatic Cancer
Gene >> SP4
| 1. | |||||||||||
| Journal: | Cancer Res. 2004 Sep 15;64(18):6740-9. | ||||||||||
| Title: | Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells. | ||||||||||
| Author: | Abdelrahim, Maen|Smith, Roger 3rd|Burghardt, Robert|Safe, Stephen | ||||||||||
| PMID: | 15374992 | ||||||||||
| 2. | |||||||||||
| Journal: | Endocrinology. 2004 Dec;145(12):5774-85. Epub 2004 Sep 2. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins. | ||||||||||
| Author: | Hong, Jun|Samudio, Ismael|Liu, Shengxi|Abdelrahim, Maen|Safe, Stephen | ||||||||||
| PMID: | 15345676 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2005 Apr 22;280(16):16508-13. Epub 2005 Mar 8. | ||||||||||
| Title: | Induction of endoplasmic reticulum-induced stress genes in Panc-1 pancreatic cancer cells is dependent on Sp proteins. | ||||||||||
| Author: | Abdelrahim, Maen|Liu, Shengxi|Safe, Stephen | ||||||||||
| PMID: | 15760841 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2006 Jun 23;345(1):292-301. Epub 2006 May 2. | ||||||||||
| Title: | Regulation of vascular endothelial growth factor receptor-2 expression in pancreatic cancer cells by Sp proteins. | ||||||||||
| Author: | Higgins, Kelly J|Abdelrahim, Maen|Liu, Shengxi|Yoon, Kyungsil|Safe, Stephen | ||||||||||
| PMID: | 16678129 | ||||||||||
| 5. | |||||||||||
| Journal: | J Natl Cancer Inst. 2006 Jun 21;98(12):855-68. | ||||||||||
| Title: | Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation. | ||||||||||
| Author: | Abdelrahim, Maen|Baker, Cheryl H|Abbruzzese, James L|Safe, Stephen | ||||||||||
| PMID: | 16788159 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2007 Apr 1;67(7):3286-94. | ||||||||||
| Title: | Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. | ||||||||||
| Author: | Abdelrahim, Maen|Baker, Cheryl H|Abbruzzese, James L|Sheikh-Hamad, David|Liu, Shengxi|Cho, Sung Dae|Yoon, Kyungsil|Safe, Stephen | ||||||||||
| PMID: | 17409437 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cancer Res. 2009 Jul;7(7):1169-78. | ||||||||||
| Title: | p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells. | ||||||||||
| Author: | Lee, Syng-Ook|Chintharlapalli, Sudhakar|Liu, Shengxi|Papineni, Sabitha|Cho, Sung Dae|Yoon, Kyungsil|Safe, Stephen | ||||||||||
| PMID: | 19584258 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Pharmacol. 2010 Aug;78(2):226-36. | ||||||||||
| Title: | Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a. | ||||||||||
| Author: | Jutooru, Indira|Chadalapaka, Gayathri|Abdelrahim, Maen|Basha, Md Riyaz|Samudio, Ismael|Konopleva, Marina|Andreeff, Michael|Safe, Stephen | ||||||||||
| PMID: | 20488920 | ||||||||||
| 9. | |||||||||||
| Journal: | J Biol Chem. 2010 Aug 13;285(33):25332-44. | ||||||||||
| Title: | Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation. | ||||||||||
| Author: | Jutooru, Indira|Chadalapaka, Gayathri|Lei, Ping|Safe, Stephen | ||||||||||
| PMID: | 20538607 | ||||||||||
| 10. | |||||||||||
| Journal: | BMC Cancer. 2012 Nov 30;12:564. | ||||||||||
| Title: | Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs. | ||||||||||
| Author: | Gandhy, Shruti U|Kim, Kyounghyun|Larsen, Lesley|Rosengren, Rhonda J|Safe, Stephen | ||||||||||
| PMID: | 23194063 | ||||||||||
| 11. | |||||||||||
| Journal: | Curr Med Chem. 2012;19(22):3779-86. | ||||||||||
| Title: | Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy. | ||||||||||
| Author: | Sankpal, Umesh T|Maliakal, Pius|Bose, Debashish|Kayaleh, Omar|Buchholz, Daniel|Basha, Riyaz | ||||||||||
| PMID: | 22725697 | ||||||||||
| 12. | |||||||||||
| Journal: | Carcinogenesis. 2013 Dec;34(12):2870-9. | ||||||||||
| Title: | Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors. | ||||||||||
| Author: | Nair, Vijayalekshmi|Pathi, Satya|Jutooru, Indira|Sreevalsan, Sandeep|Basha, Riyaz|Abdelrahim, Maen|Samudio, Ismael|Safe, Stephen | ||||||||||
| PMID: | 23803693 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Carcinog. 2014 Feb;53 Suppl 1:E53-61. | ||||||||||
| Title: | Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors. | ||||||||||
| Author: | Pathi, Satya|Li, Xi|Safe, Stephen | ||||||||||
| PMID: | 23670891 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Cell Biol. 2014 Jul;34(13):2382-95. | ||||||||||
| Title: | Mechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agents. | ||||||||||
| Author: | Jutooru, Indira|Guthrie, Aaron S|Chadalapaka, Gayathri|Pathi, Satya|Kim, KyoungHyun|Burghardt, Robert|Jin, Un-Ho|Safe, Stephen | ||||||||||
| PMID: | 24732804 | ||||||||||
| 15. | |||||||||||
| Journal: | J Biol Chem. 2014 Oct 3;289(40):27692-701. | ||||||||||
| Title: | Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer: role of specificity protein (Sp) transcription factors. | ||||||||||
| Author: | Nair, Vijayalekshmi|Sreevalsan, Sandeep|Basha, Riyaz|Abdelrahim, Maen|Abudayyeh, Ala|Rodrigues Hoffman, Aline|Safe, Stephen | ||||||||||
| PMID: | 25143389 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):26359-72. | ||||||||||
| Title: | Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC. | ||||||||||
| Author: | Gandhy, Shruti U|Imanirad, Parisa|Jin, Un-Ho|Nair, Vijayalekshmi|Hedrick, Eric|Cheng, Yating|Corton, J Christopher|Kim, KyoungHyun|Safe, Stephen | ||||||||||
| PMID: | 26317792 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2016 Apr 19;7(16):22245-56. | ||||||||||
| Title: | Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells. | ||||||||||
| Author: | Hedrick, Erik|Cheng, Yating|Jin, Un-Ho|Kim, Kyounghyun|Safe, Stephen | ||||||||||
| PMID: | 26967243 | ||||||||||
| 18. | |||||||||||
| Journal: | J Biol Chem. 2016 Dec 30;291(53):27122-27133. | ||||||||||
| Title: | Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer. | ||||||||||
| Author: | Kasiappan, Ravi|Jutooru, Indira|Karki, Keshav|Hedrick, Erik|Safe, Stephen | ||||||||||
| PMID: | 27875298 | ||||||||||
| 19. | |||||||||||
| Journal: | Biol Chem. 2018 Mar 28;399(4):321-335. | ||||||||||
| Title: | Metformin-induced anticancer activities: recent insights. | ||||||||||
| Author: | Safe, Stephen|Nair, Vijayalekshmi|Karki, Keshav | ||||||||||
| PMID: | 29272251 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2018 Feb 1;13(2):e0192264. | ||||||||||
| Title: | Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer. | ||||||||||
| Author: | Cheng, Yating|Imanirad, Parisa|Jutooru, Indira|Hedrick, Erik|Jin, Un-Ho|Rodrigues Hoffman, Aline|Leal de Araujo, Jeann|Morpurgo, Benjamin|Golovko, Andrei|Safe, Stephen | ||||||||||
| PMID: | 29389953 | ||||||||||