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Gene >> SP4

Journal: Mol Pharmacol. 2005 Aug;68(2):317-29. Epub 2005 May 9.
Title: Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins.
Author: Abdelrahim, Maen|Safe, Stephen
PMID: 15883203
Journal: Cancer Res. 2007 Apr 1;67(7):3286-94.
Title: Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
Author: Abdelrahim, Maen|Baker, Cheryl H|Abbruzzese, James L|Sheikh-Hamad, David|Liu, Shengxi|Cho, Sung Dae|Yoon, Kyungsil|Safe, Stephen
PMID: 17409437
Journal: Int J Cancer. 2009 Oct 15;125(8):1965-74.
Title: Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Abdelrahim, Maen|Abudayyeh, Ala|Jutooru, Indira|Chadalapaka, Gayathri|Wu, Fei|Mertens-Talcott, Susanne|Vanderlaag, Kathy|Cho, Sung Dae|Smith, Roger 3rd|Safe, Stephen
PMID: 19582879
Journal: Mol Cancer Res. 2011 Feb;9(2):195-202.
Title: GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway.
Author: Pathi, Satya S|Jutooru, Indira|Chadalapaka, Gayathri|Sreevalsan, Sandeep|Anand, S|Thatcher, Gregory Rj|Safe, Stephen
PMID: 21156786
Journal: BMC Cancer. 2011 Aug 24;11:371.
Title: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Lei, Ping|Pathi, Satya|Safe, Stephen
PMID: 21864401
Journal: Nutr Cancer. 2011;63(7):1133-42.
Title: Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells.
Author: Pathi, Satya S|Lei, Ping|Sreevalsan, Sandeep|Chadalapaka, Gayathri|Jutooru, Indira|Safe, Stephen
PMID: 21919647
Journal: PLoS One. 2012;7(10):e48208.
Title: Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Jutooru, Indira|Chadalapaka, Gayathri|Nair, Vijayalekshmi|Lee, Syng-Ook|Safe, Stephen
PMID: 23110215
Journal: BMC Cancer. 2012 Nov 30;12:564.
Title: Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.
Author: Gandhy, Shruti U|Kim, Kyounghyun|Larsen, Lesley|Rosengren, Rhonda J|Safe, Stephen
PMID: 23194063
Journal: Mol Nutr Food Res. 2013 Sep;57(9):1638-48.
Title: The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis.
Author: Noratto, Giuliana D|Jutooru, Indira|Safe, Stephen|Angel-Morales, Gabriela|Mertens-Talcott, Susanne U
PMID: 23471840
Journal: Curr Colorectal Cancer Rep. 2013 Dec;9(4):350-357.
Title: REACTIVE OXYGEN SPECIES AND COLORECTAL CANCER.
Author: Sreevalsan, Sandeep|Safe, Stephen
PMID: 25584043
Journal: Mol Cancer Ther. 2013 Nov;12(11):2483-93.
Title: The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.
Author: Sreevalsan, Sandeep|Safe, Stephen
PMID: 24030632
Journal: Nutr Cancer. 2013;65(3):494-504.
Title: Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a.
Author: Del Follo-Martinez, Armando|Banerjee, Nivedita|Li, Xiangrong|Safe, Stephen|Mertens-Talcott, Susanne
PMID: 23530649
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E53-61.
Title: Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors.
Author: Pathi, Satya|Li, Xi|Safe, Stephen
PMID: 23670891
Journal: Oncol Rep. 2014 Jan;31(1):117-24.
Title: Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a.
Author: Li, Wei|Liu, Min|Xu, Yun-Fei|Feng, Yuan|Che, Jian-Ping|Wang, Guang-Chun|Zheng, Jun-Hua
PMID: 24173369
Journal: BMC Cancer. 2015 Dec 16;15:974.
Title: Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors.
Author: Li, Xi|Pathi, Satya S|Safe, Stephen
PMID: 26673922
Journal: Oncotarget. 2016 Apr 19;7(16):22245-56.
Title: Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.
Author: Hedrick, Erik|Cheng, Yating|Jin, Un-Ho|Kim, Kyounghyun|Safe, Stephen
PMID: 26967243
Journal: Mol Pharmacol. 2018 Oct;94(4):1187-1196.
Title: Bortezomib Targets Sp Transcription Factors in Cancer Cells.
Author: Karki, Keshav|Harishchandra, Sneha|Safe, Stephen
PMID: 30115673