Primary Site >> Liver Cancer
Gene >> SOX9
| 1. | |||||||||||
| Journal: | FEBS Lett. 2012 Dec 14;586(24):4362-70. | ||||||||||
| Title: | MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Yanqiong|Guo, Xiaodong|Xiong, Lu|Kong, Xiangying|Xu, Ying|Liu, Chunfang|Zou, Lin|Li, Zhiwei|Zhao, Jingmin|Lin, Na | ||||||||||
| PMID: | 23178713 | ||||||||||
| 2. | |||||||||||
| Journal: | Diagn Pathol. 2012 Apr 19;7:44. | ||||||||||
| Title: | Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Guo, Xiaodong|Xiong, Lu|Sun, Ting|Peng, Ruiyun|Zou, Lin|Zhu, Haiyan|Zhang, Jing|Li, Hanwei|Zhao, Jingmin | ||||||||||
| PMID: | 22515642 | ||||||||||
| 3. | |||||||||||
| Journal: | Hepatology. 2013 Apr;57(4):1607-19. | ||||||||||
| Title: | Constitutive Notch2 signaling induces hepatic tumors in mice. | ||||||||||
| Author: | Dill, Michael T|Tornillo, Luigi|Fritzius, Thorsten|Terracciano, Luigi|Semela, David|Bettler, Bernhard|Heim, Markus H|Tchorz, Jan S | ||||||||||
| PMID: | 23175466 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2014 Aug 15;74(16):4515-25. | ||||||||||
| Title: | beta-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma. | ||||||||||
| Author: | Mokkapati, Sharada|Niopek, Katharina|Huang, Le|Cunniff, Kegan J|Ruteshouser, E Cristy|deCaestecker, Mark|Finegold, Milton J|Huff, Vicki | ||||||||||
| PMID: | 24848510 | ||||||||||
| 5. | |||||||||||
| Journal: | Anticancer Agents Med Chem. 2015;15(3):291-7. | ||||||||||
| Title: | The cytotoxic and mechanistic effects of aaptamine on hepatocellular carcinoma. | ||||||||||
| Author: | Li, Qiao-lu|Zhang, Ping-ping|Wang, Pei-qin|Yu, Hao-bing|Sun, Fan|Hu, Wen-zheng|Wu, Wen-hui|Zhang, Xin|Chen, Fei|Chu, Zhi-yong|Zhang, Jun-ping|Chen, Shun-shen|Lin, Hou-wen | ||||||||||
| PMID: | 25403168 | ||||||||||
| 6. | |||||||||||
| Journal: | Hepatology. 2015 May;61(5):1627-42. | ||||||||||
| Title: | IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism. | ||||||||||
| Author: | Yamada, Daisaku|Rizvi, Sumera|Razumilava, Nataliya|Bronk, Steven F|Davila, Jaime I|Champion, Mia D|Borad, Mitesh J|Bezerra, Jorge A|Chen, Xin|Gores, Gregory J | ||||||||||
| PMID: | 25580681 | ||||||||||
| 7. | |||||||||||
| Journal: | Cell. 2015 Aug 13;162(4):766-79. | ||||||||||
| Title: | Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. | ||||||||||
| Author: | Font-Burgada, Joan|Shalapour, Shabnam|Ramaswamy, Suvasini|Hsueh, Brian|Rossell, David|Umemura, Atsushi|Taniguchi, Koji|Nakagawa, Hayato|Valasek, Mark A|Ye, Li|Kopp, Janel L|Sander, Maike|Carter, Hannah|Deisseroth, Karl|Verma, Inder M|Karin, Michael | ||||||||||
| PMID: | 26276631 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Biochem Biophys. 2015 Nov;73(2):553-558. | ||||||||||
| Title: | Effects of shRNA-Mediated SOX9 Inhibition on Cell Proliferation and Apoptosis in Human HCC Cell Line Hep3B Mediated by Ultrasound-Targeted Microbubble Destruction (UTMD). | ||||||||||
| Author: | Xue, Yan|Yang, Guilun|Wang, Changmei|Li, Xiaodong|Du, Guijin | ||||||||||
| PMID: | 27352352 | ||||||||||
| 9. | |||||||||||
| Journal: | |||||||||||
| Title: | Roles of E-cadherin in Hepatocarcinogenesis | ||||||||||
| Author: | Maeda, Shin|Nakagawa, Hayato | ||||||||||
| PMID: | 29787164 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncotarget. 2016 May 17;7(20):29371-86. | ||||||||||
| Title: | Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/beta-catenin signaling. | ||||||||||
| Author: | Leung, Carmen Oi-Ning|Mak, Wing-Nga|Kai, Alan Ka-Lun|Chan, Kwan-Shuen|Lee, Terence Kin-Wah|Ng, Irene Oi-Lin|Lo, Regina Cheuk-Lam | ||||||||||
| PMID: | 27105493 | ||||||||||
| 11. | |||||||||||
| Journal: | Sci Rep. 2016 Oct 11;6:34856. | ||||||||||
| Title: | Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin. | ||||||||||
| Author: | Xia, Honghai|Cao, Jun|Li, Qing|Lv, Yang|Jia, Weidong|Ren, Weihua|Cheng, Qingyu|Song, Xiaoyuan|Xu, Geliang | ||||||||||
| PMID: | 27725724 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2016 Dec;81(Pt A):195-207. | ||||||||||
| Title: | Fibrous nests in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome. | ||||||||||
| Author: | Desert, Romain|Mebarki, Sihem|Desille, Mireille|Sicard, Marie|Lavergne, Elise|Renaud, Stephanie|Bergeat, Damien|Sulpice, Laurent|Perret, Christine|Turlin, Bruno|Clement, Bruno|Musso, Orlando | ||||||||||
| PMID: | 27545991 | ||||||||||
| 13. | |||||||||||
| Journal: | Sci Rep. 2016 Jul 26;6:30489. | ||||||||||
| Title: | SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma. | ||||||||||
| Author: | Kawai, Takayuki|Yasuchika, Kentaro|Ishii, Takamichi|Miyauchi, Yuya|Kojima, Hidenobu|Yamaoka, Ryoya|Katayama, Hokahiro|Yoshitoshi, Elena Yukie|Ogiso, Satoshi|Kita, Sadahiko|Yasuda, Katsutaro|Fukumitsu, Ken|Komori, Junji|Hatano, Etsuro|Kawaguchi, Yoshiya|Ue | ||||||||||
| PMID: | 27457505 | ||||||||||
| 14. | |||||||||||
| Journal: | Am J Transl Res. 2016 May 15;8(5):2159-68. eCollection 2016. | ||||||||||
| Title: | miR-138 suppresses cell proliferation and invasion by inhibiting SOX9 in hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Yahui|Zhang, Wei|Liu, Kai|Liu, Songyang|Ji, Bai|Wang, Yingchao | ||||||||||
| PMID: | 27347323 | ||||||||||
| 15. | |||||||||||
| Journal: | Hepatology. 2016 Jul;64(1):117-29. | ||||||||||
| Title: | Sox9 regulates self-renewal and tumorigenicity by promoting symmetrical cell division of cancer stem cells in hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Chungang|Liu, Limei|Chen, Xuejiao|Cheng, Jiamin|Zhang, Heng|Shen, Junjie|Shan, Juanjuan|Xu, Yanmin|Yang, Zhi|Lai, Maode|Qian, Cheng | ||||||||||
| PMID: | 26910875 | ||||||||||
| 16. | |||||||||||
| Journal: | Hum Pathol. 2017 Apr;62:232-241. | ||||||||||
| Title: | Molecular and cytogenomic profiling of hepatic adenocarcinoma expressing inhibinA, a mimicker of neuroendocrine tumors: proposal to reclassify as "cholangioblastic variant of intrahepatic cholangiocarcinoma". | ||||||||||
| Author: | Braxton, David R|Saxe, Debra|Damjanov, Nevena|Stashek, Kristen|Shroff, Stuti|Morrissette, Jennifer D|Tondon, Rashmi|Furth, Emma E | ||||||||||
| PMID: | 28232156 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2017 Nov 15;12(11):e0187384. | ||||||||||
| Title: | Notch signaling and progenitor/ductular reaction in steatohepatitis. | ||||||||||
| Author: | Morell, Carola M|Fiorotto, Romina|Meroni, Marica|Raizner, Aileen|Torsello, Barbara|Cadamuro, Massimiliano|Spagnuolo, Gaia|Kaffe, Eleanna|Sutti, Salvatore|Albano, Emanuele|Strazzabosco, Mario | ||||||||||
| PMID: | 29140985 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2017 Nov 9;12(11):e0187814. | ||||||||||
| Title: | SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types. | ||||||||||
| Author: | Richtig, Georg|Aigelsreiter, Ariane|Schwarzenbacher, Daniela|Ress, Anna Lena|Adiprasito, Jan Basri|Stiegelbauer, Verena|Hoefler, Gerald|Schauer, Silvia|Kiesslich, Tobias|Kornprat, Peter|Winder, Thomas|Eisner, Florian|Gerger, Armin|Stoeger, Herbert|Stauber | ||||||||||
| PMID: | 29121666 | ||||||||||
| 19. | |||||||||||
| Journal: | World J Gastroenterol. 2017 Oct 7;23(37):6833-6844. | ||||||||||
| Title: | STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury. | ||||||||||
| Author: | Abe, Mitsuhiko|Yoshida, Takafumi|Akiba, Jun|Ikezono, Yu|Wada, Fumitaka|Masuda, Atsutaka|Sakaue, Takahiko|Tanaka, Toshimitsu|Iwamoto, Hideki|Nakamura, Toru|Sata, Michio|Koga, Hironori|Yoshimura, Akihiko|Torimura, Takuji | ||||||||||
| PMID: | 29085226 | ||||||||||
| 20. | |||||||||||
| Journal: | Nat Commun. 2017 Oct 30;8(1):1185. | ||||||||||
| Title: | Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. | ||||||||||
| Author: | Liu, Jessica Aijia|Rao, Yanxia|Cheung, May Pui Lai|Hui, Man-Ning|Wu, Ming-Hoi|Chan, Lo-Kong|Ng, Irene Oi-Lin|Niu, Ben|Cheah, Kathryn S E|Sharma, Rakesh|Hodgson, Louis|Cheung, Martin | ||||||||||
| PMID: | 29084958 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Lett. 2017 Dec 1;410:20-31. | ||||||||||
| Title: | Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Chang|Ren, Yi-Fan|Dong, Jian|Ke, Meng-Yun|Ma, Feng|Monga, Satdarshan P S|Wu, Rongqian|Lv, Yi|Zhang, Xu-Feng | ||||||||||
| PMID: | 28942012 | ||||||||||
| 22. | |||||||||||
| Journal: | Diagn Pathol. 2017 Aug 1;12(1):56. | ||||||||||
| Title: | Variation of stemness markers expression in tumor nodules from synchronous multi-focal hepatocellular carcinoma - an immunohistochemical study. | ||||||||||
| Author: | Lo, Regina Cheuk-Lam|Leung, Carmen Oi-Ning|Chok, Kenneth Siu-Ho|Ng, Irene Oi-Lin | ||||||||||
| PMID: | 28764740 | ||||||||||
| 23. | |||||||||||
| Journal: | Anticancer Res. 2017 Jul;37(7):3397-3403. | ||||||||||
| Title: | A Novel mTOR Inhibitor; Anthracimycin for the Treatment of Human Hepatocellular Carcinoma. | ||||||||||
| Author: | Hayashi, Tomoyuki|Yamashita, Taro|Okada, Hikari|Oishi, Naoki|Sunagozaka, Hajime|Nio, Kouki|Hayashi, Takehiro|Hara, Yasumasa|Asahina, Yoshiro|Yoshida, Mariko|Hashiba, Tomomi|Suda, Tsuyoshi|Shirasaki, Takayoshi|Igarashi, Yasuhiro|Miyanouchi, Koji|Yamashita, | ||||||||||
| PMID: | 28668827 | ||||||||||
| 24. | |||||||||||
| Journal: | Gastroenterology. 2017 Apr;152(5):1161-1173.e1. | ||||||||||
| Title: | Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice. | ||||||||||
| Author: | Song, Chun-Qing|Li, Yingxiang|Mou, Haiwei|Moore, Jill|Park, Angela|Pomyen, Yotsawat|Hough, Soren|Kennedy, Zachary|Fischer, Andrew|Yin, Hao|Anderson, Daniel G|Conte, Darryl Jr|Zender, Lars|Wang, Xin Wei|Thorgeirsson, Snorri|Weng, Zhiping|Xue, Wen | ||||||||||
| PMID: | 27956228 | ||||||||||
| 25. | |||||||||||
| Journal: | Hepatology. 2018 May;67(5):1807-1822. | ||||||||||
| Title: | beta-catenin deficiency in hepatocytes aggravates hepatocarcinogenesis driven by oncogenic beta-catenin and MET. | ||||||||||
| Author: | Liang, Yan|Feng, Yun|Zong, Min|Wei, Xu-Fu|Lee, Jin|Feng, Yukuan|Li, Hairi|Yang, Guang-Shun|Wu, Zhong-Jun|Fu, Xiang-Dong|Feng, Gen-Sheng | ||||||||||
| PMID: | 29152756 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Lett. 2018 May 1;421:161-169. | ||||||||||
| Title: | Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy. | ||||||||||
| Author: | Lin, Yun-Kai|Fang, Zheng|Jiang, Tian-Yi|Wan, Zheng-Hua|Pan, Yu-Fei|Ma, Yun-Han|Shi, Yuan-Yuan|Tan, Ye-Xiong|Dong, Li-Wei|Zhang, Yong-Jie|Wang, Hong-Yang | ||||||||||
| PMID: | 29452147 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncotarget. 2017 Dec 22;9(5):5892-5905. | ||||||||||
| Title: | YAP-associated chromosomal instability and cholangiocarcinoma in mice. | ||||||||||
| Author: | Rizvi, Sumera|Fischbach, Samantha R|Bronk, Steven F|Hirsova, Petra|Krishnan, Anuradha|Dhanasekaran, Renumathy|Smadbeck, James B|Smoot, Rory L|Vasmatzis, George|Gores, Gregory J | ||||||||||
| PMID: | 29464042 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncogene. 2018 Jun;37(24):3229-3242. | ||||||||||
| Title: | Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice. | ||||||||||
| Author: | Wang, Jingxiao|Dong, Mingjie|Xu, Zhong|Song, Xinhua|Zhang, Shanshan|Qiao, Yu|Che, Li|Gordan, John|Hu, Kaiwen|Liu, Yan|Calvisi, Diego F|Chen, Xin | ||||||||||
| PMID: | 29545603 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Res. 2018 Aug 15;78(16):4445-4451. | ||||||||||
| Title: | Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma. | ||||||||||
| Author: | Hill, Margaret A|Alexander, William B|Guo, Bing|Kato, Yasutaka|Patra, Krushna|O'Dell, Michael R|McCall, Matthew N|Whitney-Miller, Christa L|Bardeesy, Nabeel|Hezel, Aram F | ||||||||||
| PMID: | 29871934 | ||||||||||
| 30. | |||||||||||
| Journal: | Gene. 2018 Aug 8;679:138-149. | ||||||||||
| Title: | LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma. | ||||||||||
| Author: | Yan, Shaoying|Shan, Xuefeng|Chen, Ke|Liu, Yuyang|Yu, Gangfeng|Chen, Qiuxu|Zeng, Tao|Zhu, Liying|Dang, Hao|Chen, Fengjiao|Ling, Jiaji|Huang, Ailong|Tang, Hua | ||||||||||
| PMID: | 30098428 | ||||||||||
| 31. | |||||||||||
| Journal: | Am J Pathol. 2018 Aug 27. pii: S0002-9440(18)30136-6. | ||||||||||
| Title: | Pten Haplodeficiency Accelerates Liver Tumor Growth in miR-122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells. | ||||||||||
| Author: | Tu, Wei-Ling|You, Li-Ru|Tsou, Ann-Ping|Chen, Chun-Ming | ||||||||||
| PMID: | 30165041 | ||||||||||
| 32. | |||||||||||
| Journal: | Sci Rep. 2018 Sep 3;8(1):13168. | ||||||||||
| Title: | Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model. | ||||||||||
| Author: | Anfuso, Beatrice|El-Khobar, Korri E|Ie, Susan I|Avellini, Claudio|Radillo, Oriano|Raseni, Alan|Tiribelli, Claudio|Sukowati, Caecilia H C | ||||||||||
| PMID: | 30177788 | ||||||||||
| 33. | |||||||||||
| Journal: | Hepatobiliary Pancreat Dis Int. 2018 Oct;17(5):416-422. | ||||||||||
| Title: | Incomplete radiofrequency ablation promotes the development of CD133(+) cancer stem cells in hepatocellular carcinoma cell line HepG2 via inducing SOX9 expression. | ||||||||||
| Author: | Yuan, Chun-Wang|Wang, Zhen-Chang|Liu, Kai|Liu, Dong-Jie | ||||||||||
| PMID: | 30262419 | ||||||||||